Search Results - "Díaz, Fernando"
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1
Unravelling the Interplay between Extracellular Acidosis and Immune Cells
Published in Mediators of inflammation (01-01-2018)“…The development of an acidic tissue environment is a hallmark of a variety of inflammatory processes and solid tumors. However, little attention has been paid…”
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2
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
Published in Science (American Association for the Advancement of Science) (01-02-2013)“…Microtubule-stabilizing agents (MSAs) are efficacious chemotherapeutic drugs widely used for the treatment of cancer. Despite the importance of MSAs for…”
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3
Social sentiment segregation: Evidence from Twitter and Google Trends in Chile during the COVID-19 dynamic quarantine strategy
Published in PloS one (13-07-2021)“…The Chilean health authorities have implemented a sanitary strategy known as dynamic quarantine or strategic quarantine to cope with the COVID-19 pandemic…”
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4
Protein Folding and Mechanisms of Proteostasis
Published in International journal of molecular sciences (28-07-2015)“…Highly sophisticated mechanisms that modulate protein structure and function, which involve synthesis and degradation, have evolved to maintain cellular…”
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5
role for LATERAL ORGAN BOUNDARIES‐DOMAIN 16 during the interaction Arabidopsis–Meloidogyne spp. provides a molecular link between lateral root and root‐knot nematode feeding site development
Published in The New phytologist (01-07-2014)“…Plant endoparasitic nematodes induce the formation of their feeding cells by injecting effectors from the esophageal glands into root cells. Although vascular…”
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6
Assessing the impact of small firm dynamics on public mental health amid the pandemic in Latin America
Published in BMC public health (10-07-2024)“…The aim of our study is to examine the relationship between the economic activity of small firms and the mental well-being of the population in five Latin…”
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7
Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials
Published in BMJ (Online) (13-01-2021)“…To evaluate sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists in patients with type 2 diabetes at…”
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8
Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint
Published in The European journal of neuroscience (01-03-2024)“…Environmental enrichment (EE) has been shown to produce beneficial effects in addiction disorders; however, due to its configurational complexity, the…”
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9
Structural Basis of Microtubule Stabilization by Laulimalide and Peloruside A
Published in Angewandte Chemie International Edition (03-02-2014)“…Laulimalide and peloruside A are microtubule‐stabilizing agents (MSAs), the mechanism of action on microtubules of which is poorly defined. Here, using X‐ray…”
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10
Root-knot nematodes induce gall formation by recruiting developmental pathways of post-embryonic organogenesis and regeneration to promote transient pluripotency
Published in The New phytologist (01-07-2020)“…• Root-knot nematodes (RKNs; Meloidogyne spp.) induce new post-embryogenic organs within the roots (galls) where they stablish and differentiate nematode…”
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11
The late consolidation of an aversive memory is promoted by VTA dopamine release in the dorsal hippocampus
Published in The European journal of neuroscience (01-02-2021)“…The hippocampus has been implicated in the processing and storage of aversive memories but the precise mechanisms by which these memories persist in time…”
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12
Ultrafast Charge Transfer and Relaxation at a Donor–Acceptor Interface
Published in The journal of physical chemistry. B (12-08-2021)“…The efficiency of charge separation in organic photovoltaic materials is crucially determined by the underlying dynamics of the charge transfer (CT) excitons…”
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13
Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2021)“…Tubulin-targeted chemotherapy has proven to be a successful and wide spectrum strategy against solid and liquidmalignancies. Therefore, new ways to modulate…”
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14
Heterogeneous responses in Google Trends measures of well-being to the COVID-19 dynamic quarantines in Chile
Published in Scientific reports (25-08-2022)“…We study how the Chilean population’s well-being responded to the strategy implemented by their health authorities, known as Dynamic Quarantine , to contain…”
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15
Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
Published in Nature communications (09-03-2017)“…BKM120 (Buparlisib) is one of the most advanced phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of cancer, but it interferes as an off-target…”
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16
Working memory load modulates oscillatory activity and the distribution of fast frequencies across frontal theta phase during working memory maintenance
Published in Neurobiology of learning and memory (01-09-2021)“…Working memory (WM) is a keystone of our cognitive abilities. Increasing load has been shown to dampen its performance and affect oscillatory neural activity…”
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High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design
Published in Scientific reports (09-03-2018)“…Microtubule-targeting agents that bind at the colchicine-site of tubulin are of particular interest in antitumoral therapy due to their dual mechanism of…”
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18
Anterior Nasal Superior Oblique Tendon Syndrome: A Case Series
Published in American journal of ophthalmology (01-12-2024)“…To evaluate the clinical characteristics and management of patients with an anteriorly and nasally inserted superior oblique tendon. Retrospective…”
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19
Structural model for differential cap maturation at growing microtubule ends
Published in eLife (10-03-2020)“…Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for…”
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20
Neuronal Subtype Specification within a Lineage by Opposing Temporal Feed-Forward Loops
Published in Cell (25-11-2009)“…Neural progenitors generate distinct cell types at different stages, but the mechanisms controlling these temporal transitions are poorly understood. In the…”
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