Search Results - "Di, Liuqing"
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Lactobacillus murinus Improved the Bioavailability of Orally Administered Glycyrrhizic Acid in Rats
Published in Frontiers in microbiology (24-04-2020)“…Intestinal microbiota has been extensively studied in the context of host health benefit, and it has recently become clear that the gut microbiota influences…”
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Preparation of Curcumin-Eudragit ® E PO Solid Dispersions with Gradient Temperature through Hot-Melt Extrusion
Published in Molecules (Basel, Switzerland) (17-08-2021)“…Hot-melt extrusion (HME) has great advantages for the preparation of solid dispersion (SD), for instance, it does not require any organic solvents…”
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Optimization of the Preparation Conditions of Borneol-Modified Ginkgolide Liposomes by Response Surface Methodology and Study of Their Blood Brain Barrier Permeability
Published in Molecules (Basel, Switzerland) (31-01-2018)“…Ginkgolides (GG), containing ginkgolide A (GA), ginkgolide B (GB) and ginkgolide C (GC), are mainly prescribed for ischemic stroke and cerebral infarction…”
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4
Aconiti Lateralis Radix Praeparata as Potential Anticancer Herb: Bioactive Compounds and Molecular Mechanisms
Published in Frontiers in pharmacology (18-05-2022)“…(Fuzi in Chinese) is a traditional herbal medicine widely used in China and other Asian countries. In clinical practice, it is often used to treat heart…”
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Improved Oral Bioavailability Using a Solid Self-Microemulsifying Drug Delivery System Containing a Multicomponent Mixture Extracted from Salvia miltiorrhiza
Published in Molecules (Basel, Switzerland) (08-04-2016)“…The active ingredients of salvia (dried root of Salvia miltiorrhiza) include both lipophilic (e.g., tanshinone IIA, tanshinone I, cryptotanshinone and…”
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6
Gather wisdom to overcome barriers: Well-designed nano-drug delivery systems for treating gliomas
Published in Acta pharmaceutica Sinica. B (01-03-2022)“…Due to the special physiological and pathological characteristics of gliomas, most therapeutic drugs are prevented from entering the brain. To improve the poor…”
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Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma
Published in Bioactive materials (01-07-2022)“…Glioma is one of the most malignant primary tumors affecting the brain. The efficacy of therapeutics for glioma is seriously compromised by the restriction of…”
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Integrated Serum and Fecal Metabolomics Study of Collagen-Induced Arthritis Rats and the Therapeutic Effects of the Zushima Tablet
Published in Frontiers in pharmacology (14-08-2018)“…The Zushima tablet (ZT) has been used for decades in the clinical treatment of rheumatoid arthritis (RA) in China. However, its therapeutic mechanism is…”
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Synergistic inhibition of metastatic breast cancer by dual-chemotherapy with excipient-free rhein/DOX nanodispersions
Published in Journal of nanobiotechnology (26-08-2020)“…Abstract Background The management of metastatic cancer remains a major challenge in cancer therapy worldwide. The targeted delivery of chemotherapeutic drugs…”
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Pharmacokinetics of rosmarinic acid in rats by LC-MS/MS: absolute bioavailability and dose proportionality
Published in RSC advances (01-01-2017)“…Rosmarinic acid (RA), one of the main bioactive compounds of Rosmarinus officinalis L., exhibits diverse pharmacological effects. However, its oral absolute…”
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The Bioavailability of Glycyrrhizinic Acid Was Enhanced by Probiotic Lactobacillus rhamnosus R0011 Supplementation in Liver Fibrosis Rats
Published in Nutrients (11-12-2022)“…Glycyrrhizinic acid (GL) is clinically applied to treat liver injury, and the bioavailability of orally administered GL is closely related to the gut…”
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12
Microneedle-Assisted Percutaneous Delivery of a Tetramethylpyrazine-Loaded Microemulsion
Published in Molecules (Basel, Switzerland) (21-11-2017)“…This study examined the efficacy of the percutaneous delivery of a tetramethylpyrazine-loaded microemulsion (TMP-ME) on skin pretreated with microneedles (MN)…”
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13
Preparation of osthole-polymer solid dispersions by hot-melt extrusion for dissolution and bioavailability enhancement
Published in International journal of pharmaceutics (25-04-2014)“…The aim of this study was to investigate the potential of solid dispersion to improve the dissolution rate and bioavailability of osthole (Ost), a coumarin…”
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14
A novel antimicrobial peptide found in Pelophylax nigromaculatus
Published in Journal of Genetic Engineering and Biotechnology (23-05-2022)“…• For AMPs, disulphide bond can affect their biofunction and cytotoxicity. • Frog skin secretion is a reservoir to delve valuable peptides. • AMPs-antibiotics…”
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15
Mineral medicine: from traditional drugs to multifunctional delivery systems
Published in Chinese medicine (10-02-2022)“…Mineral drugs are an important constituent of traditional Chinese medicine (TCM). Taking minerals that contain heavy metals as drugs is a very national…”
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Influence of Jiegeng on Pharmacokinetic Properties of Flavonoids and Saponins in Gancao
Published in Molecules (Basel, Switzerland) (21-09-2017)“…Jiegeng Gancao decoction, which is composed of Jiegeng and Gancao at a weight ratio of 1:2, was widely used for treating pharyngalgia and cough for thousands…”
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Therapeutic effects of daphnetin on adjuvant-induced arthritic rats
Published in Journal of ethnopharmacology (20-11-2008)“…Daphnetin was regarded as the mark compound for quality control of Zushima-Pian, a traditional Chinese medicine tablet for treating rheumatoid arthritis (RA)…”
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A Comparative Pharmacokinetic Study by UHPLC-MS/MS of Main Active Compounds after Oral Administration of Zushima-Gancao Extract in Normal and Adjuvant-Induced Arthritis Rats
Published in Molecules (Basel, Switzerland) (22-01-2018)“…A sensitive and rapid ultra high-performance liquid-chromatography tandem mass spectrometry (UHPLC-MS/MS) method has been applied to investigate the influence…”
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Nanotechnologies meeting natural sources: Engineered lipoproteins for precise brain disease theranostics
Published in Asian journal of pharmceutical sciences (01-09-2023)“…Biological nanotechnologies have provided considerable opportunities in the management of malignancies with delicate design and negligible toxicity, from…”
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Orally delivered polycurcumin responsive to bacterial reduction for targeted therapy of inflammatory bowel disease
Published in Drug delivery (01-01-2017)“…Inflammatory bowel disease (IBD) such as Crohn's disease and ulcerative colitis is a chronic autoimmune disease affecting nearly five million people worldwide…”
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