Search Results - "Dhillon, Navneet"

Extracellular vesicles: novel communicators in lung diseases by Mohan, Aradhana, Agarwal, Stuti, Clauss, Matthias, Britt, Nicholas S, Dhillon, Navneet K

“…The lung is the organ with the highest vascular density in the human body. It is therefore perceivable that the endothelium of the lung contributes…”
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Persistent circulation of soluble and extracellular vesicle‐linked Spike protein in individuals with postacute sequelae of COVID‐19 by Craddock, Vaughn, Mahajan, Aatish, Spikes, Leslie, Krishnamachary, Balaji, Ram, Anil K., Kumar, Ashok, Chen, Ling, Chalise, Prabhakar, Dhillon, Navneet K.

“…ABSTRACT SARS‐CoV‐2, the causative agent of COVID‐19 disease, has resulted in the death of millions worldwide since the beginning of the pandemic in December…”
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Who Drives the Chronic Obstructive Pulmonary Disease Bus? Protease-Rich Extracellular Vesicles in Cigarette Smoke-associated Alveolar Damage by Craddock, Vaughn D, Dhillon, Navneet K

“…Craddock and Dhillon discuss the study by Madison et al on the link between cigarette smoking (CS) and the production of extracellular vesicles (EVs) armed…”
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NADPH oxidase-mediated endothelial injury in HIV- and opioid-induced pulmonary arterial hypertension by Agarwal, Stuti, Sharma, Himanshu, Chen, Ling, Dhillon, Navneet K

“…We previously demonstrated that the combined exposure of human pulmonary microvascular endothelial cells (HPMECs) to morphine and viral protein(s) results in…”
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Macrophage‐derived extracellular vesicles mediate smooth muscle hyperplasia: role of altered miRNA cargo in response to HIV infection and substance abuse by Sharma, Himanshu, Chinnappan, Mahendran, Agarwal, Stuti, Dalvi, Pranjali, Gunewardena, Sumedha, O'Brien-Ladner, Amy, Dhillon, Navneet K.

“…ABSTRACT Our previous studies consistently demonstrate enhanced pulmonary vascular remodeling in HIV–infected intravenous drug users, and in simian…”
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Extracellular vesicle‐mediated endothelial apoptosis and EV‐associated proteins correlate with COVID‐19 disease severity by Krishnamachary, Balaji, Cook, Christine, Kumar, Ashok, Spikes, Leslie, Chalise, Prabhakar, Dhillon, Navneet K.

“…Coronavirus disease‐2019 (COVID‐19), caused by the novel severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2), has lead to a global pandemic with a…”
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Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities by Kumar, Rahul, Aktay-Cetin, Öznur, Craddock, Vaughn, Morales-Cano, Daniel, Kosanovic, Djuro, Cogolludo, Angel, Perez-Vizcaino, Francisco, Avdeev, Sergey, Kumar, Ashok, Ram, Anil Kumar, Agarwal, Stuti, Chakraborty, Ananya, Savai, Rajkumar, de Jesus Perez, Vinicio, Graham, Brian B, Butrous, Ghazwan, Dhillon, Navneet K

“…The Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to…”
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Analysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells by Chinnappan, Mahendran, Gunewardena, Sumedha, Chalise, Prabhakar, Dhillon, Navneet K.

“…We previously reported enhanced proliferation of smooth muscle cells on the combined exposure of HIV proteins and cocaine leading to the development of…”
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Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer by Dhillon, Navneet, Aggarwal, Bharat B, Newman, Robert A, Wolff, Robert A, Kunnumakkara, Ajaikumar B, Abbruzzese, James L, Ng, Chaan S, Badmaev, Vladimir, Kurzrock, Razelle

“…Purpose: Pancreatic cancer is almost always lethal, and the only U.S. Food and Drug Administration–approved therapies for it, gemcitabine and erlotinib,…”
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Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial by Rugo, Hope S, Dr Prof, Seneviratne, Lasika, MD, Beck, J Thaddeus, MD, Glaspy, John A, Prof, Peguero, Julio A, MD, Pluard, Timothy J, MD, Dhillon, Navneet, MD, Hwang, Leon Christopher, MD, Nangia, Chaitali, MD, Mayer, Ingrid A, MD, Meiller, Timothy F, Prof, Chambers, Mark S, Prof, Sweetman, Robert W, MD, Sabo, J Randy, MPH, Litton, Jennifer K, MD

“…Summary Background Stomatitis is a class effect associated with the inhibition of mTOR and is associated with everolimus therapy for breast cancer. Topical…”
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Downregulation of Bone Morphogenetic Protein Receptor Axis During HIV-1 and Cocaine-Mediated Pulmonary Smooth Muscle Hyperplasia: Implications for HIV-Related Pulmonary Arterial Hypertension by Dalvi, Pranjali, O’Brien-Ladner, Amy, Dhillon, Navneet K

“…OBJECTIVE—Our previous findings support an additive effect of cocaine to HIV infection in the development of pulmonary arteriopathy through enhanced…”
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HIV-1/cocaine induced oxidative stress disrupts tight junction protein-1 in human pulmonary microvascular endothelial cells: role of Ras/ERK1/2 pathway by Dalvi, Pranjali, Wang, Kun, Mermis, Joel, Zeng, Ruoxi, Sanderson, Miles, Johnson, Sara, Dai, Yuqiao, Sharma, Garima, Ladner, Amy O'Brien, Dhillon, Navneet K

“…Intravenous drug use (IVDU) is the major risk factor in the development of HIV-related pulmonary arterial hypertension (HRPAH); however, the pathogenesis of…”
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Extracellular Vesicle TGF-β1 Is Linked to Cardiopulmonary Dysfunction in Human Immunodeficiency Virus by Krishnamachary, Balaji, Mahajan, Aatish, Kumar, Ashok, Agarwal, Stuti, Mohan, Aradhana, Chen, Ling, Hsue, Priscilla Y, Chalise, Prabhakar, Morris, Alison, Dhillon, Navneet K

“…Extracellular vesicles (EVs) have emerged as important mediators in cell-cell communication; however, their relevance in pulmonary hypertension (PH) secondary…”
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Drug abuse and HIV-related pulmonary hypertension: double hit injury by Harter, Zachery J, Agarwal, Stuti, Dalvi, Pranjali, Voelkel, Norbert F, Dhillon, Navneet K

“…Improved survival among HIV-1-infected individuals with the advent of antiretroviral therapy has clearly led to a greater prevalence of noninfectious…”
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Analysis of MicroRNA Cargo in Circulating Extracellular Vesicles from HIV-Infected Individuals with Pulmonary Hypertension by Mahajan, Aatish, Gunewardena, Sumedha, Morris, Alison, Clauss, Matthias, Dhillon, Navneet K

“…The risk of developing pulmonary hypertension (PH) in people living with HIV is at least 300-fold higher than in the general population, and illicit drug use…”
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Enhanced autophagy in pulmonary endothelial cells on exposure to HIV-Tat and morphine: Role in HIV-related pulmonary arterial hypertension by Dalvi, Pranjali, Sharma, Himanshu, Chinnappan, Mahendran, Sanderson, Miles, Allen, Julie, Zeng, Ruoxi, Choi, Augustine, O'Brien-Ladner, Amy, Dhillon, Navneet K.

“…Intravenous drug use is one of the major risk factors for HIV-infection in HIV-related pulmonary arterial hypertension patients. We previously demonstrated…”
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Viral Bad News Sent by EVAIL by Clauss, Matthias, Chelvanambi, Sarvesh, Cook, Christine, ElMergawy, Rabab, Dhillon, Navneet

“…This article reviews the current knowledge on how viruses may utilize Extracellular Vesicle Assisted Inflammatory Load (EVAIL) to exert pathologic activities…”
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HIV-Nef Protein Persists in the Lungs of Aviremic Patients with HIV and Induces Endothelial Cell Death by Chelvanambi, Sarvesh, Bogatcheva, Natalia V, Bednorz, Mariola, Agarwal, Stuti, Maier, Bernhard, Alves, Nathan J, Li, Wei, Syed, Farooq, Saber, Manal M, Dahl, Noelle, Lu, Hongyan, Day, Richard B, Smith, Patricia, Jolicoeur, Paul, Yu, Qigui, Dhillon, Navneet K, Weissmann, Norbert, Twigg Iii, Homer L, Clauss, Matthias

“…It remains a mystery why HIV-associated end-organ pathologies persist in the era of combined antiretroviral therapy (ART). One possible mechanism is the…”
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HIV-1 Tat co-operates with IFN-gamma and TNF-alpha to increase CXCL10 in human astrocytes by Williams, Rachel, Yao, Honghong, Dhillon, Navneet K, Buch, Shilpa J

“…HIV-associated neurological disorders (HAND) are estimated to affect 60% of the HIV infected population. HIV-encephalitis (HIVE), the pathological correlate of…”
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Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling by Mermis, Joel, Gu, Haihua, Xue, Bing, Li, Fang, Tawfik, Ossama, Buch, Shilpa, Bartolome, Sonja, O'Brien-Ladner, Amy, Dhillon, Navneet K

“…Human immunodeficiency virus (HIV) infected patients are at increased risk for the development of pulmonary arterial hypertension (PAH). Recent reports have…”
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