Search Results - "Dharmakumar, Rohan"
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Building a Unified Mechanistic Insight Into the Bimodal Pattern of Edema in Reperfused Acute Myocardial Infarctions
Published in Journal of the American College of Cardiology (18-08-2015)“…[...]to determine temporal changes of edema in the same subject pertaining to given pathology (e.g., ischemia or ischemia followed by reperfusion), serial…”
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Intramyocardial hemorrhage drives fatty degeneration of infarcted myocardium
Published in Nature communications (27-10-2022)“…Sudden blockage of arteries supplying the heart muscle contributes to millions of heart attacks (myocardial infarction, MI) around the world. Although…”
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Chronic heart failure following hemorrhagic myocardial infarction: mechanism, treatment and outlook
Published in Cell Stress (01-02-2023)“…Myocardial infarction (MI), the blockage of arterial blood supply of the heart, is among the most common causes of death worldwide. Even when patients receive…”
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Validation of Contrast-Enhanced Magnetic Resonance Imaging to Monitor Regenerative Efficacy After Cell Therapy in a Porcine Model of Convalescent Myocardial Infarction
Published in Circulation (New York, N.Y.) (24-12-2013)“…BACKGROUND—Magnetic resonance imaging (MRI) in the CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction (CADUCEUS) trial revealed that…”
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Reperfused hemorrhagic myocardial infarction in rats
Published in PloS one (02-12-2020)“…Intramyocardial hemorrhage following reperfusion is strongly associated with major adverse cardiovascular events in myocardial infarction (MI) patients; yet…”
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Assessment of intramyocardial hemorrhage with dark-blood T2-weighted cardiovascular magnetic resonance
Published in Journal of cardiovascular magnetic resonance (15-07-2021)“…Intramyocardial hemorrhage (IMH) within myocardial infarction (MI) is associated with major adverse cardiovascular events. Bright-blood T2*-based…”
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Quantification of myocardial hemorrhage using T2 cardiovascular magnetic resonance at 1.5T with ex-vivo validation
Published in Journal of cardiovascular magnetic resonance (30-09-2021)“…T2* cardiovascular magnetic resonance (CMR) is commonly used in the diagnosis of intramyocardial hemorrhage (IMH). For quantifying IMH with T2* CMR, despite…”
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Native T1 Mapping by 3-T CMR Imaging for Characterization of Chronic Myocardial Infarctions
Published in JACC. Cardiovascular imaging (01-09-2015)“…Abstract Objectives The purpose of this study was to investigate whether native T1 maps at 3-T can reliably characterize chronic myocardial infarctions (MIs)…”
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Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy
Published in PloS one (02-12-2014)“…Epicardial injection of heart-derived cell products is safe and effective post-myocardial infarction (MI), but clinically-translatable transendocardial…”
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Retrospective assessment of at-risk myocardium in reperfused acute myocardial infarction patients using contrast-enhanced balanced steady-state free-precession cardiovascular magnetic resonance at 3T with SPECT validation
Published in Journal of cardiovascular magnetic resonance (15-03-2021)“…Contrast-enhanced (CE) steady-state free precession (SSFP) CMR at 1.5T has been shown to be a valuable alternative to T2-based methods for the detection and…”
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