Search Results - "Dhar, Kakali"

Leptin-induced ER-α-positive breast cancer cell viability and migration is mediated by suppressing CCN5-signaling via activating JAK/AKT/STAT-pathway by Haque, Inamul, Ghosh, Arnab, Acup, Seth, Banerjee, Snigdha, Dhar, Kakali, Ray, Amitabha, Sarkar, Sandipto, Kambhampati, Suman, Banerjee, Sushanta K

“…In menopausal women, one of the critical risk factors for breast cancer is obesity/adiposity. It is evident from various studies that leptin, a 16 kDa protein…”
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Deficiency of CCN5/WISP-2-Driven Program in breast cancer Promotes Cancer Epithelial cells to mesenchymal stem cells and Breast Cancer growth by Das, Amlan, Dhar, Kakali, Maity, Gargi, Sarkar, Sandipto, Ghosh, Arnab, Haque, Inamul, Dhar, Gopal, Banerjee, Snigdha, Banerjee, Sushanta K.

“…Breast cancer progression and relapse is conceivably due to tumor initiating cells (TICs)/cancer stem cells. EMT (epithelial-mesenchymal-transition)-signaling…”
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CYR61/CCN1 Regulates dCK and CTGF and Causes Gemcitabine-resistant Phenotype in Pancreatic Ductal Adenocarcinoma by Maity, Gargi, Ghosh, Arnab, Gupta, Vijayalaxmi, Haque, Inamul, Sarkar, Sandipto, Das, Amlan, Dhar, Kakali, Bhavanasi, Sneha, Gunewardena, Sumedha S, Von Hoff, Daniel D, Mallik, Sanku, Kambhampati, Suman, Banerjee, Sushanta K, Banerjee, Snigdha

“…Pancreatic ductal adenocarcinoma (PDAC) develops extrinsic- and intrinsic-resistant phenotypes to prevent chemotherapies from entering into the cells by…”
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Cyr61/CCN1 signaling is critical for epithelial-mesenchymal transition and stemness and promotes pancreatic carcinogenesis by Haque, Inamul, Mehta, Smita, Majumder, Monami, Dhar, Kakali, De, Archana, McGregor, Douglas, Van Veldhuizen, Peter J, Banerjee, Sushanta K, Banerjee, Snigdha

“…Despite recent advances in outlining the mechanisms involved in pancreatic carcinogenesis, precise molecular pathways and cellular lineage specification…”
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Pancreatic Tumor Cell Secreted CCN1/Cyr61 Promotes Endothelial cell migration and Aberrant Neovascularization by Maity, Gargi, Mehta, Smita, Haque, Inamul, Dhar, Kakali, Sarkar, Sandipto, Banerjee, Sushanta K., Banerjee, Snigdha

“…The complex signaling networks between cancer cells and adjacent endothelial cells make it challenging to unravel how cancer cells send extracellular messages…”
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Crocetin inhibits pancreatic cancer cell proliferation and tumor progression in a xenograft mouse model by Dhar, Animesh, Mehta, Smita, Dhar, Gopal, Dhar, Kakali, Banerjee, Snigdha, Van Veldhuizen, Peter, Campbell, Donald R, Banerjee, Sushanta K

“…Crocetin, a carotenoid compound derived from saffron, has long been used as a traditional ancient medicine against different human diseases including cancer…”
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Tumor cell-derived PDGF-B potentiates mouse mesenchymal stem cells-pericytes transition and recruitment through an interaction with NRP-1 by Dhar, Kakali, Dhar, Gopal, Majumder, Monami, Haque, Inamul, Mehta, Smita, Van Veldhuizen, Peter J, Banerjee, Sushanta K, Banerjee, Snigdha

“…New blood vessel formation, or angiogenic switch, is an essential event in the development of solid tumors and their metastatic growth. Tumor blood vessel…”
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Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2 by Dhar, Gopal, Banerjee, Snigdha, Dhar, Kakali, Tawfik, Ossama, Mayo, Matthew S, Vanveldhuizen, Peter J, Banerjee, Sushanta K

“…CCN5/WISP-2 is overexpressed in noninvasive breast cancer cells and tissue samples, whereas its expression is minimal or undetected in invasive conditions…”
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VEGF-A165 Induces Human Aortic Smooth Muscle Cell Migration by Activating Neuropilin-1-VEGFR1-PI3K Axis by Banerjee, Snigdha, Mehta, Smita, Haque, Inamul, Sengupta, Krishanu, Dhar, Kakali, Kambhampati, Suman, Van Veldhuizen, Peter J., Banerjee, Sushanta K.

“…Vascular smooth muscle cells (SMCs), one of the major cell types of the vascular wall, play a critical role in the process of angiogenesis under both…”
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Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1 by Banerjee, Snigdha, Sengupta, Krishanu, Dhar, Kakali, Mehta, Smita, D'Amore, Patricia A., Dhar, Gopal, Banerjee, Sushanta K.

“…Motility of vascular smooth muscle cells (SMCs) is an essential step for both normal and pathologic angiogenesis. We report here that breast tumor cells, such…”
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Epidermal Growth Factor Induces WISP-2/CCN5 Expression in Estrogen Receptor-α-Positive Breast Tumor Cells through Multiple Molecular Cross-talks by Banerjee, Snigdha, Sengupta, Krishanu, Saxena, Neela K, Dhar, Kakali, Banerjee, Sushanta K

“…Epidermal growth factor (EGF) is a mitogen for estrogen receptor (ER)–positive breast tumor cells, and it has been proven that EGF occasionally mimicked…”
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Gemcitabine Sensitivity is Improved in Pancreatic Cancer by CYR61/CCN1‐Depletion‐Mediated Upregulation of dCK and Suppression of CTGF by Ghosh, Arnab, Maity, Gargi, Gupta, Vijaylaxmi, Haque, Inamul, Sarkar, Sandipto, Das, Amlan, Dhar, Kakali, Bhavanasi, Sneha, Gunewardena, Sumedha S, Von Hoff, Daniel D, Mallik, Sanku, Kambhampati, Suman, Banerjee, Sushanta, Banerjee, Snigdha

“…Introduction Pancreatic ductal adenocarcinoma (PDAC) develops resistance (both extrinsic and intrinsic) by preventing chemotherapeutic agents from entering…”
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Leptin-induced ER-[alpha]-positive breast cancer cell viability and migration is mediated by suppressing CCN5-signaling via activating JAK/AKT/STAT-pathway by Haque, Inamul, Ghosh, Arnab, Acup, Seth, Banerjee, Snigdha, Dhar, Kakali, Ray, Amitabha, Sarkar, Sandipto, Kambhampati, Suman, Banerjee, Sushanta K

“…Background In menopausal women, one of the critical risk factors for breast cancer is obesity/adiposity. It is evident from various studies that leptin, a 16…”
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Abstract 2330: Transcription factor MAZ promotes cell growth and aggressive behavior of human pancreatic cancer cells by Maity, Gargi, Sarkar, Sandipto, Dhar, Kakali, Dhar, Gopal, Haque, Inamul, Banerjee, Sushanta K., Banerjee, Snigdha

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is the fourth most common cancer in the United States and the eighth worldwide. PDAC is most aggressive type…”
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Insulin-like growth factor-1 (IGF-1) induces WISP-2/CCN5 via multiple molecular cross-talks and is essential for mitogenic switch by IGF-1 axis in estrogen receptor-positive breast tumor cells by DHAR, Kakali, BANERJEE, Snigdha, DHAR, Gopal, SENGUPTA, Krishanu, BANERJEE, Sushanta K

“…Previously, we have shown that the expression of Wnt-1-induced signaling protein-2 (WISP-2), also known as CCN5, can be regulated by multiple stimulants in…”
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Novel method to differentiate 3T3 L1 cells in vitro to produce highly sensitive adipocytes for a GLUT4 mediated glucose uptake using fluorescent glucose analog by Vishwanath, Divya, Srinivasan, Harini, Patil, Manjunath S., Seetarama, Sowmya, Agrawal, Sachin Kumar, Dixit, M. N., Dhar, Kakali

“…Adipocytes play a vital role in glucose metabolism. 3T3 L1 pre adipocytes after differentiation to adipocytes serve as excellent in vitro models and are useful…”
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Abstract 5540: CCN5/WISP-2 prevents leptin-induced breast cancer cell growth and migration by Haque, Inamul, Banerjee, Snigdha, Dhar, Kakali, Chattopadhyay, Indranil, Ray, Amitabha, Banerjee, Sushanta K

“…Abstract In menopausal women, one of the important risk factors for breast cancer is obesity/adiposity. Despite multiple studies, the biological mechanism by…”
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Abstract 1314: Estrogen receptor-α is activated in breast ductal epithelial cells by CCN5 in CCN5-conditional tri-transgenic mice by Majumder, Monami, Banerjee, Snigdha, Mehta, Smita, De, Archana, Dhar, Kakali, Tawfik, Ossama, Larson, Melissa A., Banerjee, Sushanta K.

“…Abstract Estrogen receptor-alpha (ER-α) is localized in the nuclei of approximately 3-7% of normal resting breast epithelial cells with a higher proportion in…”
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Abstract 2962: Role of Cyr61 in the progression of pancreatic cancer by Mehta, Smita, Dhar, Kakali, Haque, Inamul, Majumder, Monami, McGregor, Douglas H., Banerjee, Sushanta K., Banerjee, Snigdha

“…Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is the fourth most common cause of cancer in men and fifth in women in the United States. The overall survival…”
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Abstract 4222: CCN5 deficient MCF-7 side population exhibits stem cell like behavior and formed aggressive tumor in xenograft model by Dhar, Kakali, Banerjee, Snigdha, Slusser, Joyce, Majumder, Monami, Banerjee, Sushanta K.

“…Abstract The side population (SP) has been identified in a variety of solid tumor cell lines including human breast cancer cell lines. This population of cells…”
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