Search Results - "Dhanasekaran, S M"

Repression of E-cadherin by the polycomb group protein EZH2 in cancer by Cao, Q, Yu, J, Dhanasekaran, S M, Kim, J H, Mani, R-S, Tomlins, S A, Mehra, R, Laxman, B, Cao, X, Kleer, C G, Varambally, S, Chinnaiyan, A M

“…Enhancer of zeste homolog 2 (EZH2) is a critical component of the polycomb-repressive complex 2 (PRC2), which is involved in gene silencing and histone H3…”
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SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression by Tiwari, R, Pandey, S K, Goel, S, Bhatia, V, Shukla, S, Jing, X, Dhanasekaran, S M, Ateeq, B

“…Colorectal cancer (CRC) is the third most common cancer in the world, and second leading cause of cancer deaths in the US. Although, anti-EGFR therapy is…”
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Correction: SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression by Tiwari, R., Pandey, S. K., Goel, S., Bhatia, V., Shukla, S., Jing, X., Dhanasekaran, S. M., Ateeq, B.

“…A Correction to this paper has been published: https://doi.org/10.1038/s41389-021-00305-2…”
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The polycomb group protein EZH2 is involved in progression of prostate cancer by Chinnaiyan, Arul M, Varambally, Sooryanarayana, Dhanasekaran, Saravana M, Zhou, Ming, Barrette, Terrence R, Kumar-Sinha, Chandan, Sanda, Martin G, Ghosh, Debashis, Pienta, Kenneth J, Sewalt, Richard G. A. B, Otte, Arie P, Rubin, Mark A

“…Prostate cancer is a leading cause of cancer-related death in males and is second only to lung cancer. Although effective surgical and radiation treatments…”
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Delineation of prognostic biomarkers in prostate cancer by Chinnaiyan, Arul M, Dhanasekaran, Saravana M, Barrette, Terrence R, Ghosh, Debashis, Shah, Rajal, Varambally, Sooryanarayana, Kurachi, Kotoku, Pienta, Kenneth J, Rubin, Mark A

“…Prostate cancer is the most frequently diagnosed cancer in American men. Screening for prostate-specific antigen (PSA) has led to earlier detection of prostate…”
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Re: Next-Generation RNA Sequencing-Based Biomarker Characterization of Chromophobe Renal Cell Carcinoma and Related Oncocytic Neoplasms by Laguna, M Pilar

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Integrative Genomics Analysis Reveals Silencing of β-Adrenergic Signaling by Polycomb in Prostate Cancer by Yu, Jindan, Cao, Qi, Mehra, Rohit, Laxman, Bharathi, Yu, Jianjun, Tomlins, Scott A., Creighton, Chad J., Dhanasekaran, Saravana M., Shen, Ronglai, Chen, Guoan, Morris, David S., Marquez, Victor E., Shah, Rajal B., Ghosh, Debashis, Varambally, Sooryanarayana, Chinnaiyan, Arul M.

“…The Polycomb group (PcG) protein EZH2 possesses oncogenic properties for which the underlying mechanism is unclear. We integrated in vitro cell line, in vivo…”
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Isolation and characterization of a transforming growth factor-beta Type II receptor cDNA from Xenopus laevis by Dhanasekaran, S M, Vempati, U D, Kondaiah, P

“…Transforming Growth Factor-beta (TGF-beta) and their receptors have been characterized from many organisms. Two TGF-beta signaling receptors called Type I and…”
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Molecular Characterization of TMPRSS2-ERG Gene Fusion in the NCI-H660 Prostate Cancer Cell Line: A New Perspective for an Old Model by Mertz, Kirsten D., Setlur, Sunita R., Dhanasekaran, Saravana M., Demichelis, Francesca, Perner, Sven, Tomlins, Scott, Tchinda, Joëlle, Laxman, Bharathi, Vessella, Robert L., Beroukhimt, Rameen, Lee, Charles, Chinnaiyan, Arul M., Rubin, Mark A.

“…Recent studies have established that a significant fraction of prostate cancers harbor a signature gene fusion between the 5' region of androgen-regulated…”
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Feature Selection and Molecular Classification of Cancer Using Genetic Programming by Yu, Jianjun, Yu, Jindan, Almal, Arpit A., Dhanasekaran, Saravana M., Ghosh, Debashis, Worzel, William P., Chinnaiyan, Arul M.

“…Despite important advances in microarray-based molecular classification of tumors, its application in clinical settings remains formidable. This is in part due…”
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Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer by Tomlins, Scott A., Rhodes, Daniel R., Perner, Sven, Dhanasekaran, Saravana M., Mehra, Rohit, Sun, Xiao-Wei, Varambally, Sooryanarayana, Cao, Xuhong, Tchinda, Joelle, Kuefer, Rainer, Lee, Charles, Montie, James E., Shah, Rajal B., Pienta, Kenneth J., Rubin, Mark A., Chinnaiyan, Arul M.

“…Recurrent chromosomal rearrangements have not been well characterized in common carcinomas. We used a bioinformatics approach to discover candidate oncogenic…”
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α-Methylacyl Coenzyme A Racemase as a Tissue Biomarker for Prostate Cancer by Rubin, Mark A, Zhou, Ming, Dhanasekaran, Saravana M, Varambally, Sooryanarayana, Barrette, Terrence R, Sanda, Martin G, Pienta, Kenneth J, Ghosh, Debashis, Chinnaiyan, Arul M

“…CONTEXT Molecular profiling of prostate cancer has led to the identification of candidate biomarkers and regulatory genes. Discoveries from these genome-scale…”
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FIZZ1 Stimulation of Myofibroblast Differentiation by Liu, Tianju, Dhanasekaran, Saravana M., Jin, Hong, Hu, Biao, Tomlins, Scott A., Chinnaiyan, Arul M., Phan, Sem H.

“…Bleomycin-induced pulmonary fibrosis is characterized by inflammation, emergence of myofibroblasts, and deposition of extracellular matrix. In an attempt to…”
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Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty by Dhanasekaran, Saravana Mohan, Dash, Atreya, Yu, Jianjun, Maine, Ira P, Laxman, Bharathi, Tomlins, Scott A, Creighton, Chad J, Menon, Anjana, Rubin, Mark A, Chinnaiyan, Arul M

“…ABSTRACT Testosterone production surges during puberty and orchestrates massive growth and reorganization of the prostate gland, and this glandular…”
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A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines by Chay, Christopher H, Cooper, Carlton R, Gendernalik, James D, Dhanasekaran, Saravana M, Chinnaiyan, Arul M, Rubin, Mark A, Schmaier, Alvin H, Pienta, Kenneth J

“…To identify genes important in prostate cancer metastatic to bone. Bone-specific metastasis is a common feature of prostate cancer and a significant cause of…”
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