Search Results - "Dhanani, Jayesh A."

Pharmacokinetics of Total and Unbound Cefazolin during Veno-Arterial Extracorporeal Membrane Oxygenation: A Case Report by Dhanani, Jayesh A, Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C, Abdul-Aziz, Mohd H, Roberts, Jason A

“…Extra-corporeal membrane oxygenation (ECMO) therapy could affect effective drug concentrations via adsorption onto the oxygenator or associated circuit. We…”
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Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions by Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle, Roberts, Jason A.

“…Microdialysis is a technique used to measure the unbound antibiotic concentration in the interstitial spaces, the target site of action. In vitro recovery…”
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Pulmonary infections complicating ARDS by Luyt, Charles-Edouard, Bouadma, Lila, Morris, Andrew Conway, Dhanani, Jayesh A., Kollef, Marin, Lipman, Jeffrey, Martin-Loeches, Ignacio, Nseir, Saad, Ranzani, Otavio T., Roquilly, Antoine, Schmidt, Matthieu, Torres, Antoni, Timsit, Jean-François

“…Pulmonary infection is one of the main complications occurring in patients suffering from acute respiratory distress syndrome (ARDS). Besides traditional risk…”
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A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models by Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F., Roberts, Jason A.

“…Background Nebulised antibiotics are frequently used for the prevention or treatment of ventilator-associated pneumonia. Many factors may influence pulmonary…”
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Nebulized Tranexamic Acid Therapy for Hemoptysis Associated with Submassive Pulmonary Embolism by Dhanani, Jayesh A, Roberts, Jason, Reade, Michael C

“…Hemoptysis and pulmonary embolism (PE) are life-threatening pulmonary emergencies that, when present together, create a therapeutic conundrum. We present an…”
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Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO: a case report by Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H., Roberts, Jason A.

“…•Pharmacokinetics of intravenous fluconazole and ganciclovir were measured in a patient receiving extracorporeal membrane oxygenation therapy (ECMO).•The…”
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Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model by Dhanani, Jayesh A, Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L, Wallis, Steven C, Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A, Fraser, John F

“…WHAT WE ALREADY KNOW ABOUT THIS TOPICFor most bacterial pneumonia, the lung interstitium is considered to be the site of infection, and adequate antibiotic…”
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Comparative Plasma Pharmacokinetics of Ceftriaxone and Ertapenem in Normoalbuminemia, Hypoalbuminemia, and Albumin Replacement in a Sheep Model by Dhanani, Jayesh A, Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C, Abdul-Aziz, Mohd H, Lipman, Jeffrey, Roberts, Jason A

“…Optimal concentrations of unbound antimicrobials are essential for a maximum microbiological effect. Although hypoalbuminemia and albumin fluid resuscitation…”
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COVID-19 Drug Treatments Are Prone to Sequestration in Extracorporeal Membrane Oxygenation Circuits: An Ex Vivo Extracorporeal Membrane Oxygenation Study by Dhanani, Jayesh A, Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C, Won, Hayoung, Sumi, Chandra D, Abdul-Aziz, Mohd H, Roberts, Jason A

“…Drug treatments for coronavirus disease 2019 (COVID-19) dramatically improve patient outcomes, and although extracorporeal membrane oxygenation (ECMO) has…”
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Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study by Dhanani, Jayesh A., Goodman, Steven, Ahern, Benjamin, Cohen, Jeremy, Fraser, John F., Barnett, Adrian, Diab, Sara, Bhatt, Manoj, Roberts, Jason A.

“…•Pulmonary drug distribution was compared for intravenous and nebulized radiolabeled tobramycin•A mechanically-ventilated healthy ovine model was…”
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Pharmacokinetics of Sulfamethoxazole and Trimethoprim During Venovenous Extracorporeal Membrane Oxygenation: A Case Report by Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Pandey, Saurabh, Abdul‐Aziz, Mohd H., Roberts, Jason A.

“…Extracorporeal membrane oxygenation (ECMO) therapy could affect drug concentrations via adsorption onto the oxygenator and/or associated circuit. We describe a…”
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Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation by Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R., Chan, Hak-Kim

“…Preservative-free tobramycin is commonly used as aerosolized therapy for ventilator associated pneumonia. The comparative delivery profile of the formulations…”
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Pulmonary infections complicating acute respiratory distress syndrome by Luyt, Charles-Edouard, Bouadma, Lila, Morris, Andrew Conway, Dhanani, Jayesh A, Kollef, Marin, Lipman, Jeffrey, Martin-Loeches, Ignacio, Nseir, Saad, Ranzani, Otavio T, Roquilly, Antoine, Schmidt, Matthieu, Torres, Antoni, Timsit, Jean-François

“…Pulmonary infection is one of the main complications occurring in patients suffering from acute respiratory distress syndrome (ARDS). Besides traditional risk…”
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Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions by Dhanani, Jayesh A, Parker, Suzanne L, Lipman, Jeffrey, Wallis, Steven C, Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle, Roberts, Jason A

“…Microdialysis is a technique used to measure the unbound antibiotic concentration in the interstitial spaces, the target site of action. In vitro recovery…”
Get full text