Search Results - "Dhakal, Sanjeev"
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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis
Published in The Journal of clinical investigation (15-11-2023)“…Systemic autoimmune and autoinflammatory diseases are characterized by genetic and cellular heterogeneity. While current single-cell genomics methods provide…”
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Effects of Angiotensin II Type 1A Receptor on ACE2, Neprilysin and KIM-1 in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension
Published in Frontiers in pharmacology (29-01-2021)“…Activation of the renin angiotensin system plays a pivotal role in the regulation of blood pressure, which is mainly attributed to the formation of…”
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Transcriptional Profiling of Tofacitinib Treatment in Juvenile Idiopathic Arthritis: Implications for Treatment Response Prediction
Published in Arthritis care & research (2010) (03-11-2024)“…Objectives To assess changes in gene expression following tofacitinib treatment and investigate transcription patterns as potential predictors of treatment…”
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Abstract P2036: Effects of Angiotensin II Type 1 A Receptor (AT1aR) on Renal and Urinary Biomarkers of Acute Kidney Injury in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only Renin angiotensin system (RAS) plays a key role in the pathogenesis and progression of hypertension and renal injury. Angiotensin-II (Ang-II)…”
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Abstract P2044: Renoprotective Effects of Canagliflozin in Db/db Diabetic Mice
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only Diabetes is one of the major causes of chronic kidney disease which could lead to end-stage renal disease. Previously, we have shown increased…”
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Behavioral and Physiological Interventions for Anxiety and Depression: An Overview of Nontraditional Methods
Published in Journal of creativity in mental health (02-10-2019)“…Public health, social well-being, and human rights worldwide have all been impactd by the effects of anxiety and depression. The helping fields have spent over…”
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Postdischarge Glucocorticoid Use and Clinical Outcomes of Multisystem Inflammatory Syndrome in Children
Published in JAMA network open (11-11-2022)“…Minimal data are available regarding the postdischarge treatment of multisystem inflammatory syndrome in children (MIS-C). To evaluate clinical characteristics…”
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