Search Results - "Dexter, L"
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The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs
Published in International journal of molecular sciences (25-01-2021)“…Pyruvate kinase is a key regulator in glycolysis through the conversion of phosphoenolpyruvate (PEP) into pyruvate. Pyruvate kinase exists in various isoforms…”
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Pyruvate kinase M2: A simple molecule with complex functions
Published in Free radical biology & medicine (01-11-2019)“…Pyruvate kinase M2 is a critical enzyme that regulates cell metabolism and growth under different physiological conditions. In its metabolic role, pyruvate…”
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Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase
Published in The Journal of biological chemistry (17-07-2015)“…The inflammasome is a multiprotein complex that augments the proinflammatory response by increasing the generation and cellular release of key cytokines…”
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Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice
Published in The Journal of biological chemistry (08-04-2016)“…Idiopathic pulmonary fibrosis is a disease characterized by progressive, unrelenting lung scarring, with death from respiratory failure within 2–4 years unless…”
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Group Housing of Male Mice Causes a Significant Decrease in Day to Night Changes in Mean Arterial Pressure and are Indicative of the Development of Hypertension and Cardiovascular Disease
Published in The FASEB journal (01-05-2022)“…Changes in day to night time mean arterial pressure (MAP) predict hypertension and cardiovascular diseases. When there is a decrease in day ‐ night time MAP…”
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Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity
Published in Nature communications (11-05-2017)“…Inflammasomes regulate innate immune responses by facilitating maturation of inflammatory cytokines, interleukin (IL)-1β and IL-18. NACHT, LRR and PYD…”
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PPAR-α knockout leads to elevated blood pressure response to angiotensin II infusion associated with an increase in renal α-1 Na+/K+ ATPase protein expression and activity
Published in Life sciences (1973) (01-05-2022)“…Peroxisome proliferator activated receptor alpha (PPAR-α) deletion has been shown to increase blood pressure (BP). We hypothesized that the BP increase in…”
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Chronic use of benzodiazepines: The problem that persists
Published in International journal of psychiatry in medicine (01-09-2023)“…Though clinical guidelines and policies discourage the chronic prescribing of benzodiazepines, rates of prescribing have continued to rise in the United States…”
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Learning from HBCUs: How to produce Black professionals in STEMM
Published in Cell (04-08-2022)“…Historically Black colleges and universities (HBCUs) offer high-quality education and produce leaders from various backgrounds, mainly being African American…”
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Post-translational modification of the interferon-gamma receptor alters its stability and signaling
Published in Biochemical journal (10-10-2017)“…The IFN gamma receptor 1 (IFNGR1) binds IFN-γ and activates gene transcription pathways crucial for controlling bacterial and viral infections. Although…”
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The Application of Historic Building Information Modelling (HBIM) to Cultural Heritage: A Review
Published in Heritage (01-10-2023)“…Historic Building Information Modelling (HBIM) is the application of BIM, a digital modelling and information management technique, to assets of historical…”
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Risk factors for persistent abnormality on chest radiographs at 12-weeks post hospitalisation with PCR confirmed COVID-19
Published in Respiratory research (21-05-2021)“…Abstract Background The long-term consequences of COVID-19 remain unclear. There is concern a proportion of patients will progress to develop pulmonary…”
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Psychiatric Agnosticism and the Pedagogical Problem of Learning Psychiatry as a Medical Student
Published in Academic psychiatry (01-06-2018)“…In my understanding of her thinking, our patient’s disease was a clinical syndrome generated by a pathological process, as opposed to an outcome of a traumatic…”
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544 Interleukin-6 protects renal dysfunction in mouse models of hypertension and salt-sensitive hypertension
Published in Journal of clinical and translational science (01-04-2024)“…OBJECTIVES/GOALS: We are investigating the role of IL-6 in regulating renal function by measuring mean arterial pressure (MAP), renal plasma flow (RPF) and…”
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HPV vaccine awareness and the association of trust in cancer information from physicians among males
Published in Vaccine (09-05-2017)“…Highlights • About half of the all-male sample had never heard of HPV. • Black men were the least likely to know that HPV is transmitted sexually. • Hispanic…”
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The effect of Ramadan fasting during pregnancy on perinatal outcomes: a systematic review and meta-analysis
Published in BMC pregnancy and childbirth (25-10-2018)“…Although exempt, many pregnant Muslim women partake in the daily fast during daylight hours during the month of Ramadan. In other contexts an impoverished diet…”
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SARS-CoV-2 Infection and Racial Disparities in Children: Protective Mechanisms and Severe Complications Related to MIS-C
Published in Journal of racial and ethnic health disparities (01-08-2022)“…A novel coronavirus has resulted in a pandemic with over 176 million confirmed cases and over 3.8 million recorded deaths. In the USA, SARS-CoV-2 infection has…”
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"RUN, JUMP, OR SHUFFLE ARE ALL THE SAME WHEN YOU DO IT FOR THE MAN!": The OPHR, Black Power, and the Boycott of the 1968 NYAC Meet
Published in Souls (Boulder, Colo.) (02-01-2019)“…The article examines black activists' use of sports and protest in the 1960s to elaborate on the meaning of black advancement in the period, especially Black…”
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Supporting and promoting Black physiologists: how can the APS help?
Published in American journal of physiology. Heart and circulatory physiology (01-06-2023)Get more information
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Total Synthesis of the Cyclic Dodecapeptides Wewakazole and Wewakazole B
Published in Organic letters (07-07-2017)“…The cyclic dodecapeptides wewakazole and wewakazole B have been synthesized by a divergent strategy via a common tris-proline containing oxazole octapeptide…”
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