Search Results - "Dewji, Raz"

Phase I Study of the Poly(ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination with Temozolomide in Patients with Advanced Solid Tumors by Plummer, Ruth, Jones, Christopher, Middleton, Mark, Wilson, Richard, Evans, Jeffrey, Olsen, Anna, Curtin, Nicola, Boddy, Alan, McHugh, Peter, Newell, David, Harris, Adrian, Johnson, Patrick, Steinfeldt, Heidi, Dewji, Raz, Wang, Diane, Robson, Lesley, Calvert, Hilary

“…Purpose: One mechanism of tumor resistance to cytotoxic therapy is repair of damaged DNA. Poly(ADP-ribose) polymerase (PARP)-1 is a nuclear enzyme involved in…”
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Retrospective quality control review of FDG scans in the imaging sub-study of PALETTE EORTC 62072/VEG110727: a randomized, double-blind, placebo-controlled phase III trial by Hristova, Ivalina, Boellaard, Ronald, Vogel, Wouter, Mottaghy, Felix, Marreaud, Sandrine, Collette, Sandra, Schöffski, Patrick, Sanfilippo, Roberta, Dewji, Raz, van der Graaf, Winette, Oyen, Wim J. G.

“…Purpose 18 F-Labelled fluorodeoxyglucose (FDG) can detect early changes in tumour metabolism and may be a useful quantitative imaging biomarker (QIB) for…”
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A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation by Plummer, Ruth, Lorigan, Paul, Steven, Neil, Scott, Lucy, Middleton, Mark R., Wilson, Richard H., Mulligan, Evan, Curtin, Nicola, Wang, Diane, Dewji, Raz, Abbattista, Antonello, Gallo, Jorge, Calvert, Hilary

“…Purpose poly(ADP ribose) polymerase inhibition has been shown to potentiate the cytotoxicity of DNA damaging agents. A phase I study of rucaparib and…”
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Pazopanib in advanced desmoplastic small round cell tumours: a multi-institutional experience by Frezza, Anna Maria, Benson, Charlotte, Judson, Ian R, Litiere, Saskia, Marreaud, Sandrine, Sleijfer, Stefan, Blay, Jean-Yves, Dewji, Raz, Fisher, Cyril, van der Graaf, Winette, Hayward, Larry

“…We retrospectively reviewed data from nine pre-treated metastatic desmoplastic small round cell tumour (DSRCT) patients who received pazopanib. Three patients…”
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Phase I Study of the Poly(ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination withTemozolomide in Patients with Advanced Solid Tumors by PLUMMER, Ruth, JONES, Christopher, HARRIS, Adrian, JOHNSON, Patrick, STEINFELDT, Heidi, DEWJI, Raz, WANG, Diane, ROBSON, Lesley, CALVERT, Hilary, MIDDLETON, Mark, WILSON, Richard, EVANS, Jeffrey, OLSEN, Anna, CURTIN, Nicola, BODDY, Alan, MCHUGH, Peter, NEWELL, David

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