Search Results - "Dewitt, John C"
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The 2016 WHO classification of central nervous system tumors: what neurologists need to know
Published in Current opinion in neurology (01-12-2017)“…The 2016 WHO classification of tumors of the central nervous system (2016 CNS WHO) features many changes that are relevant to neurologists treating patients…”
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Financially effective test algorithm to identify an aggressive, EGFR-amplified variant of IDH-wildtype, lower-grade diffuse glioma
Published in Neuro-oncology (Charlottesville, Va.) (06-05-2019)“…Update 3 of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW) recognizes amplification of epidermal growth factor…”
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Metastatic Lung Cancer Presenting as Monocular Blindness and Panhypopituitarism Secondary to a Pituitary Metastasis
Published in The American journal of case reports (23-04-2020)“…BACKGROUND Sellar masses are most commonly pituitary adenomas, however, about 1% of surgical resected pituitary lesions are found to be metastatic disease. It…”
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Thoracic exophytic ependymoma masquerading as a benign extra-axial tumor
Published in Journal of clinical neuroscience (01-11-2016)“…Highlights • Exophytic ependymomas can masquerade as benign extra-axial tumors. • Clinical and radiographic findings are not sufficient for diagnosis. • Safe…”
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Resolving medulloblastoma cellular architecture by single-cell genomics
Published in Nature (London) (01-08-2019)“…Medulloblastoma is a malignant childhood cerebellar tumour type that comprises distinct molecular subgroups. Whereas genomic characteristics of these subgroups…”
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Clinical Reasoning: A 67-Year-Old Woman With Abdominal Pain, Constipation, and Urinary Retention
Published in Neurology (19-07-2022)“…Meningeal melanocytomas are extremely rare, pigmented tumors of the CNS. They generally carry a favorable prognosis, although recurrence and transformation…”
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Primary age‐related tauopathy (PART) in the general autopsy setting: Not just a disease of the elderly
Published in Brain pathology (Zurich, Switzerland) (01-03-2021)“…Primary age‐related tauopathy (PART) is generally considered a diagnosis of the elderly. In this letter, the authors present data showing that the pathologic…”
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Sporadic NF2 Mosaic: Multiple spinal schwannomas presenting with severe, intractable pain following pregnancy
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01-12-2017)“…The aim of the present paper is to report undiagnosed sporadic neurofibromatosis type 2 presenting with symptomatic compressive spinal tumors following…”
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Campylobacter fetus seeding of a cavernous malformation resulting in brain abscess: case report and literature review
Published in Child's nervous system (01-12-2023)“…Microbial seeding of a cerebral cavernous malformation is an extremely rare occurrence with only 3 cases reported in the literature thus far. Campylobacter…”
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Neurosarcoidosis: Phenotypes, Approach to Diagnosis and Treatment
Published in Current rheumatology reports (01-12-2022)“…Purpose of Review The aim of this review is to provide an update of clinical presentation, diagnosis, differential diagnoses, and treatment according to recent…”
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Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations
Published in Neuro-oncology (Charlottesville, Va.) (29-11-2017)“…Due to the decreasing prevalence of IDH1 mutations in older patients, the 2016 World Health Organization (WHO) classification of brain tumors proposed not to…”
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Multiple signaling pathways converge to regulate bone-morphogenetic-protein-dependent glial gene expression
Published in Developmental neuroscience (01-01-2009)“…A fundamental problem in developmental neuroscience is understanding how extracellular cues link to complex intracellular signaling pathways to drive…”
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A Simplified Brain Blocking Protocol Optimized for the Diagnosis of Neurodegenerative Disease Saves Time and Money While Preserving Anatomic Relationships
Published in Archives of pathology & laboratory medicine (1976) (01-08-2021)“…Postmortem evaluation for neurodegenerative disease is expensive in time and materials. These challenges can be met by implementing simpler sampling protocols…”
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Case 19-2017 — A 53-Year-Old Woman with Leg Numbness and Weakness
Published in The New England journal of medicine (22-06-2017)“…A 53-year-old woman was admitted to the hospital because of progressive asymmetric hypoesthesia and weakness in the legs. Urinary retention, absence of rectal…”
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Rapid Neurological Recovery Following Partial Surgical Resection of Spinal Glioblastoma Multiforme in a Pediatric Patient Presenting With Complete Paraplegia
Published in Journal of pediatric hematology/oncology (01-11-2016)“…Pediatric spinal cord glioblastoma multiforme is a rare entity with a poor prognosis often presenting with lower extremity weakness or paralysis. Previous…”
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Clinical Reasoning: A 67-Year-Old Woman With Abdominal Pain, Constipation, and Urinary Retention
Published in Neurology (06-05-2022)“…Meningeal melanocytomas are an extremely rare, pigmented tumors of the central nervous system (CNS). They generally carry a favorable prognosis, although…”
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Multifocal metastases to choroid plexus from papillary thyroid carcinoma: illustrative case
Published in Journal of neurosurgery. Case lessons (13-09-2021)“…BACKGROUND Choroid plexus metastases are extremely rare from all types of malignancy, with only 42 cases reported in the literature thus far. Most of these…”
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Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors—A prospective study and guidelines for clinical testing
Published in Neuro-oncology advances (01-01-2023)“…Abstract Background Central nervous system (CNS) cancer is the 10th leading cause of cancer-associated deaths for adults, but the leading cause in pediatric…”
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Multifocal metastases to choroid plexus from papillary thyroid carcinoma: illustrative case
Published in Journal of neurosurgery. Case lessons (13-09-2021)“…BACKGROUNDChoroid plexus metastases are extremely rare from all types of malignancy, with only 42 cases reported in the literature thus far. Most of these…”
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The Role of Technology in Removing Barriers
Published in The Milbank quarterly (01-01-1991)“…"Assistive technology", the application of technology to the particular needs of persons with disabilities, is developing as a field in its own right…”
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