Search Results - "Dewi, Ruby E."

Improvement of paracellular transport in the Caco-2 drug screening model using protein-engineered substrates by DiMarco, Rebecca L, Hunt, Daniel R, Dewi, Ruby E, Heilshorn, Sarah C

“…Abstract The Caco-2 assay has achieved wide popularity among pharmaceutical companies in the past two decades as an in vitro method for estimation of in vivo…”
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Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels by Madl, Christopher M., LeSavage, Bauer L., Dewi, Ruby E., Lampe, Kyle J., Heilshorn, Sarah C.

“…Neural progenitor cells (NPCs) are a promising cell source to repair damaged nervous tissue. However, expansion of therapeutically relevant numbers of NPCs and…”
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Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis by Bhalla, Kavita, Hwang, Bor Jang, Dewi, Ruby E, Twaddel, William, Goloubeva, Olga G, Wong, Kwok-Kin, Saxena, Neeraj K, Biswal, Shyam, Girnun, Geoffrey D

“…A number of factors have been identified that increase the risk of hepatocellular carcinoma (HCC). Recently it has become appreciated that type II diabetes…”
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Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells by Cai, Lei, Dewi, Ruby E., Heilshorn, Sarah C.

“…Stem cell transplantation via direct injection is a minimally invasive strategy being explored for treatment of a variety of injuries and diseases. Injectable…”
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Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer by Montal, Emily D, Bhalla, Kavita, Dewi, Ruby E, Ruiz, Christian F, Haley, John A, Ropell, Ashley E, Gordon, Chris, Haley, John D, Girnun, Geoffrey D

“…Metabolic reprogramming is a key feature of malignant cells. While glucose is one of the primary substrates for malignant cells, cancer cells also display a…”
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Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling by Madl, Christopher M., LeSavage, Bauer L., Dewi, Ruby E., Dinh, Cong B., Stowers, Ryan S., Khariton, Margarita, Lampe, Kyle J., Nguyen, Duong, Chaudhuri, Ovijit, Enejder, Annika, Heilshorn, Sarah C.

“…Neural progenitor cell (NPC) culture within three-dimensional (3D) hydrogels is an attractive strategy for expanding a therapeutically relevant number of stem…”
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PGC1α Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis by BHALLA, Kavita, HWANG, Bor Jang, GIRNUN, Geoffrey D, DEWI, Ruby E, OU, Lihui, TWADDEL, William, FANG, Hong-Bin, VAFAI, Scott B, VAZQUEZ, Francesca, PUIGSERVER, Pere, BOROS, Laszlo

“…Despite the role of aerobic glycolysis in cancer, recent studies highlight the importance of the mitochondria and biosynthetic pathways as well. PPARγ…”
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Avidity-controlled hydrogels for injectable co-delivery of induced pluripotent stem cell-derived endothelial cells and growth factors by Mulyasasmita, Widya, Cai, Lei, Dewi, Ruby E., Jha, Arshi, Ullmann, Sabrina D., Luong, Richard H., Huang, Ngan F., Heilshorn, Sarah C.

“…To translate recent advances in induced pluripotent stem cell biology to clinical regenerative medicine therapies, new strategies to control the co-delivery of…”
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Transforming Growth Factor-induced Protein Promotes NF-κB-mediated Angiogenesis during Postnatal Lung Development by Liu, Min, Iosef, Cristiana, Rao, Shailaja, Domingo-Gonzalez, Racquel, Fu, Sha, Snider, Paige, Conway, Simon J, Umbach, Gray S, Heilshorn, Sarah C, Dewi, Ruby E, Dahl, Mar J, Null, Donald M, Albertine, Kurt H, Alvira, Cristina M

“…Pulmonary angiogenesis is a key driver of alveolarization. Our prior studies showed that NF-κB promotes pulmonary angiogenesis during early alveolarization…”
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YAP-dependent mechanotransduction is required for proliferation and migration on native-like substrate topography by Mascharak, Shamik, Benitez, Patrick L, Proctor, Amy C, Madl, Christopher M, Hu, Kenneth H, Dewi, Ruby E, Butte, Manish J, Heilshorn, Sarah C

“…Abstract Native vascular extracellular matrices (vECM) consist of elastic fibers that impart varied topographical properties, yet most in vitro models designed…”
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Protein-engineered hydrogels enhance the survival of induced pluripotent stem cell-derived endothelial cells for treatment of peripheral arterial disease by Foster, Abbygail A, Dewi, Ruby E, Cai, Lei, Hou, Luqia, Strassberg, Zachary, Alcazar, Cynthia A, Heilshorn, Sarah C, Huang, Ngan F

“…A key feature of peripheral arterial disease (PAD) is damage to endothelial cells (ECs), resulting in lower limb pain and restricted blood flow. Recent…”
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Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation by Cai, Lei, Dewi, Ruby E., Goldstone, Andrew B., Cohen, Jeffrey E., Steele, Amanda N., Woo, Y. Joseph, Heilshorn, Sarah C.

“…A family of shear‐thinning hydrogels for injectable encapsulation and long‐term delivery (SHIELD) has been designed and synthesized with controlled in situ…”
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Protein-engineered scaffolds for in vitro 3D culture of primary adult intestinal organoids by DiMarco, Rebecca L, Dewi, Ruby E, Bernal, Gabriela, Kuo, Calvin, Heilshorn, Sarah C

“…Though in vitro culture of primary intestinal organoids has gained significant momentum in recent years, little has been done to investigate the impact of…”
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Microfluidic analysis of extracellular matrix-bFGF crosstalk on primary human myoblast chemoproliferation, chemokinesis, and chemotaxis by Ferreira, Meghaan M, Dewi, Ruby E, Heilshorn, Sarah C

“…Exposing myoblasts to basic fibroblast growth factor (bFGF), which is released after muscle injury, results in receptor phosphorylation, faster migration, and…”
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Elastin-like Proteins to Support Peripheral Nerve Regeneration in Guidance Conduits by Suhar, Riley A, Marquardt, Laura M, Song, Shang, Buabbas, Hana, Doulames, Vanessa M, Johansson, Patrik K, Klett, Katarina C, Dewi, Ruby E, Enejder, Annika M. K, Plant, Giles W, George, Paul M, Heilshorn, Sarah C

“…Synthetic nerve guidance conduits (NGCs) offer an alternative to harvested nerve grafts for treating peripheral nerve injury (PNI). NGCs have been made from…”
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Protein–Nanoparticle Hydrogels That Self-assemble in Response to Peptide-Based Molecular Recognition by Parisi-Amon, Andreina, Lo, David D, Montoro, Daniel T, Dewi, Ruby E, Longaker, Michael T, Heilshorn, Sarah C

“…Recently, supramolecular hydrogels assembled through nonspecific interactions between polymers and nanoparticles (termed PNP systems) were reported to have…”
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Chemotaxis of human induced pluripotent stem cell-derived endothelial cells by Huang, Ngan F, Dewi, Ruby E, Okogbaa, Janet, Lee, Jerry C, Jalilrufaihah, Abdul, Heilshorn, Sarah C, Cooke, John P

“…This study examined the homing capacity of human induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) and their response to chemotactic gradients…”
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Hydrogels: Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells (Adv. Funct. Mater. 9/2015) by Cai, Lei, Dewi, Ruby E., Heilshorn, Sarah C.

“…S. C. Heilshorn and co‐workers design shear‐thinning hydrogels for injectable encapsulation and long‐term delivery (SHIELD) by combining protein‐engineering…”
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Microfluidic analysis of extracellular matrix-bFGF crosstalk on primary human myoblast chemoproliferation, chemokinesis, and chemotaxisElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ib00060b by Ferreira, Meghaan M, Dewi, Ruby E, Heilshorn, Sarah C

“…Exposing myoblasts to basic fibroblast growth factor (bFGF), which is released after muscle injury, results in receptor phosphorylation, faster migration, and…”
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