Search Results - "Dewhurst, Matthew"

Loss of hepatocyte cell division leads to liver inflammation and fibrosis by Dewhurst, Matthew R, Ow, Jin Rong, Zafer, Gözde, van Hul, Noémi K M, Wollmann, Heike, Bisteau, Xavier, Brough, David, Choi, Hyungwon, Kaldis, Philipp

“…The liver possesses a remarkable regenerative capacity based partly on the ability of hepatocytes to re-enter the cell cycle and divide to replace damaged…”
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Metabolic Remodeling during Liver Regeneration by Caldez, Matias J., Van Hul, Noémi, Koh, Hiromi W.L., Teo, Xing Qi, Fan, Jun Jun, Tan, Peck Yean, Dewhurst, Matthew R., Too, Peh Gek, Talib, S. Zakiah A., Chiang, Beatrice E., Stünkel, Walter, Yu, Hanry, Lee, Philip, Fuhrer, Tobias, Choi, Hyungwon, Björklund, Mikael, Kaldis, Philipp

“…Liver disease is linked to a decreased capacity of hepatocytes to divide. In addition, cellular metabolism is important for tissue homeostasis and…”
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The Speedy A, Cdk2, p27 triangle by R. Dewhurst, Matthew, Kaldis, Philipp

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Strikingly Low Prevalence of Atrial Fibrillation in Elderly Tanzanians by Dewhurst, Matthew J., Adams, Philip C., Gray, William K., Dewhurst, Felicity, Orega, Golda P., Chaote, Paul, Walker, Richard W.

“…Objectives To determine the prevalence of atrial fibrillation (AF) in individuals aged 70 and older in a rural African community. Design Community‐based…”
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Ambulatory Blood Pressure Monitoring to Assess the White‐Coat Effect in an Elderly East African Population by Ivy, Ashleigh, Tam, Jonathan, Dewhurst, Matthew J., Gray, William K., Chaote, Paul, Rogathi, Jane, Dewhurst, Felicity, Walker, Richard W.

“…The authors hypothesized that published hypertension rates in Tanzania were influenced by the physiological response of individuals to blood pressure (BP)…”
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Rates and predictors of three-year mortality in older people in rural Tanzania by Gray, William K, Dewhurst, Felicity, Dewhurst, Matthew J, Orega, Golda, Kissima, John, Chaote, Paul, Walker, Richard W

“…Highlights • In elderly Tanzania community-dwellers, the 3-year mortality rate was 11.1%. • Mortality correlated with blood pressure, cognition, low weight and…”
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Benefits of an integrated heart failure service at critical periods in the heart failure disease trajectory by Dewhurst, Matthew J, Thambyrajah, Jeetendra

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Presentation and mortality of patients hospitalised with acute heart failure in Botswana by Goepamang, Monkgogi, Omech, Bernard, Magafu, Mgaywa G.M.D., Mashalla, Yohana, Dewhurst, Matthew J., Majuta, Koketso Lister, Palai, Tommy Baboloki, Mwita, Julius Chacha, Mosepele, Mosepele, Gaenamong, Marea

“…Introduction: Heart failure is a common cause of hospitalisation and therefore contributes to in-hospital outcomes such as mortality. In this study we describe…”
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Undiagnosed and diagnosed diabetes mellitus among hospitalised acute heart failure patients in Botswana by Mwita, Julius Chacha, Magafu, Mgaywa Gilbert Mjungu Damas, Omech, Bernard, Tsima, Billy, Dewhurst, Matthew J, Goepamang, Monkgogi, Mashalla, Yohana

“…Objective: The objective of this study was to determine the burden of diagnosed and undiagnosed type 2 diabetes mellitus among patients hospitalised with acute…”
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Neurological disorder screening in the elderly in low-income countries by Dewhurst, Felicity, Dewhurst, Matthew J., Orega, Golda, Gray, William K., Howlett, William, Warren, Naomi, Aris, Eric, Walker, Richard W.

“…There are few data on neurological disorder prevalence from developing countries, particularly in the elderly in sub-Saharan Africa (SSA). This is in part due…”
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The prevalence of disability in older people in Hai, Tanzania by Dewhurst, Felicity, Dewhurst, Matthew J, Gray, William K, Orega, Golda, Howlett, William, Chaote, Paul, Dotchin, Catherine, Longdon, Anna R, Paddick, Stella-Maria, Walker, Richard W

“…the World Health Organization estimates that more than one billion of the world's population are disabled. Disability is associated with increasing age and…”
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High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts by Rudisch, Albin, Dewhurst, Matthew Richard, Horga, Luminita Gabriela, Kramer, Nina, Harrer, Nathalie, Dong, Meng, van der Kuip, Heiko, Wernitznig, Andreas, Bernthaler, Andreas, Dolznig, Helmut, Sommergruber, Wolfgang

“…We established co-cultures of invasive or non-invasive NSCLC cell lines and various types of fibroblasts (FBs) to more precisely characterize the molecular…”
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A Novel Quadripolar Active Fixation Left-Ventricular Pacing Lead for Cardiac Resynchronization Therapy by Chapman, Michael, Bates, Matthew G.D., Behar, Jonathan M., Williams, Ian, Dewhurst, Matthew, Monkhouse, Christopher, Hayward, Carl, Muthumala, Amal, Chow, Anthony, Linker, Nicholas J., Thornley, Andrew R., Turley, Andrew J.

“…This study sought to assess immediate and short-term performance of the Medtronic Attain Stability Quadripolar 4798 lead (Medtronic, Dublin, Ireland). Cardiac…”
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The association between disability and cognitive impairment in an elderly Tanzanian population by Dotchin, Catherine L, Paddick, Stella-Maria, Gray, William K, Kisoli, Aloyce, Orega, Golda, Longdon, Anna R, Chaote, Paul, Dewhurst, Felicity, Dewhurst, Matthew, Walker, Richard W

“…Abstract Cognitive impairment is thought to be a major cause of disability worldwide, though data from sub-Saharan Africa (SSA) are sparse. This study aimed to…”
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Assessment of left ventricular geometrical patterns and function among hypertensive patients at a tertiary hospital, Northern Tanzania by Silangei, Lairumbe Korduni, Maro, Venance Philis, Diefenthal, Helmut, Kapanda, Gibson, Dewhurst, Matthew, Mwandolela, Hery, Hamel, Ben

“…With hypertension, the cardiovascular system changes to adapt to the varying neuro-humoral and hemodynamic changes and this may lead to the development of…”
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Current Evidence and Recommendations for Cardiac Resynchronisation Therapy by Dewhurst, Matthew J, Linker, Nicholas J

“…The number of people in Europe living with symptomatic heart failure is increasing. Since its advent in the 1990s, cardiac resynchronisation therapy (CRT) has…”
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Electrocardiographic Reference Values for a Population of Older Adults in Sub-Saharan Africa by Dewhurst, Matthew J., Di Marco, Luigi Y., Dewhurst, Felicity, Adams, Philip C., Murray, Alan, Orega, Golda P., Mwita, Julius C., Walker, Richard W., Langley, Philip

“…Background/Objectives Older adults in sub‐Saharan Africa (SSA) are at greatest risk of an impending noncommunicable diseases epidemic, of which cardiac disease…”
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Electrocardiographic Assessment of Coronary Artery Disease and Stroke Risk Factors in Rural and Urban Tanzania: A Case–control Study by Walker, Richard W., MD, Dewhurst, Matthew, MBBS, Gray, William K., PhD, Jusabani, Ahmed, M Med, Aris, Eric, MD, Unwin, Nigel, PhD, Swai, Mark, MD, Adams, Philip C., MA, Mugusi, Ferdinand, MD

“…Background Although the association between cerebrovascular and coronary artery disease (CAD) is well known in high-income countries, this association is not…”
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Rates of diagnosis and treatment of neurological disorders within a prevalent population of community-dwelling elderly people in sub-Saharan Africa by Dewhurst, Felicity, Dewhurst, Matthew J, Gray, William K, Chaote, Paul, Howlett, William, Orega, Golda, Walker, Richard W

“…Abstract Background The prevalence of neurological disorders in those aged 70 years and over in the Hai district of Tanzania has been previously reported. The…”
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The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes by Tapia, Victor S., Daniels, Michael J.D., Palazón-Riquelme, Pablo, Dewhurst, Matthew, Luheshi, Nadia M., Rivers-Auty, Jack, Green, Jack, Redondo-Castro, Elena, Kaldis, Philipp, Lopez-Castejon, Gloria, Brough, David

“…Interleukin (IL)-1 family cytokines potently regulate inflammation, with the majority of the IL-1 family proteins being secreted from immune cells via…”
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