Search Results - "Dewamitta, Sita R"

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection by Fang, Rendong, Tsuchiya, Kohsuke, Kawamura, Ikuo, Shen, Yanna, Hara, Hideki, Sakai, Shunsuke, Yamamoto, Takeshi, Fernandes-Alnemri, Teresa, Yang, Ruili, Hernandez-Cuellar, Eduardo, Dewamitta, Sita R, Xu, Yanting, Qu, Huixin, Alnemri, Emad S, Mitsuyama, Masao

“…Streptococcus pneumoniae is a Gram-positive, extracellular bacterium that is responsible for significant mortality and morbidity worldwide. Pneumolysin (PLY),…”
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Toll-Like Receptor 2- and MyD88-Dependent Phosphatidylinositol 3-Kinase and Rac1 Activation Facilitates the Phagocytosis of Listeria monocytogenes by Murine Macrophages by Shen, Yanna, Kawamura, Ikuo, Nomura, Takamasa, Tsuchiya, Kohsuke, Hara, Hideki, Dewamitta, Sita R, Sakai, Shunsuke, Qu, Huixin, Daim, Sylvia, Yamamoto, Takeshi, Mitsuyama, Masao

“…Toll-like receptors (TLRs) play a key role in the innate immune response by sensing bacterial ligands. The mechanisms involved in the TLR-mediated cytokine…”
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The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL‐18 production in an inflammasome‐dependent and ‐independent manner by Tsuchiya, Kohsuke, Hara, Hideki, Fang, Rendong, Hernandez‐Cuellar, Eduardo, Sakai, Shunsuke, Daim, Sylvia, Chen, Xi, Dewamitta, Sita R., Qu, Huixin, Mitsuyama, Masao, Kawamura, Ikuo

“…Listeria monocytogenes induces the formation of inflammasomes and subsequent caspase‐1 activation, and the adaptor apoptosis‐associated speck‐like protein…”
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Erythroid‐extrinsic regulation of normal erythropoiesis by retinoic acid receptors by Dewamitta, Sita R., Joseph, Chacko, Purton, Louise E., Walkley, Carl R.

“…Summary Vitamin A and its derivatives (retinoids) are important regulators of haematopoiesis, acting via retinoic acid receptors (RARs). Epidemiological…”
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Darbepoietin-alfa has comparable erythropoietic stimulatory effects to recombinant erythropoietin whilst preserving the bone marrow microenvironment by Dewamitta, Sita R, Russell, Megan R, Nandurkar, Harshal, Walkley, Carl R

“…Erythropoiesis stimulating agents are widely used for the treatment of anemia. Recently, we reported erythroid expansion with impaired B lymphopoiesis and loss…”
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Listeriolysin O-Dependent Bacterial Entry into the Cytoplasm Is Required for Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Listeria monocytogenes by Dewamitta, Sita R, Nomura, Takamasa, Kawamura, Ikuo, Hara, Hideki, Tsuchiya, Kohsuke, Kurenuma, Takeshi, Shen, Yanna, Daim, Sylvia, Yamamoto, Takeshi, Qu, Huixin, Sakai, Shunsuke, Xu, Yanting, Mitsuyama, Masao

“…Listeriolysin O (LLO), an hly-encoded cytolysin of Listeria monocytogenes, plays an essential role in the entry of L. monocytogenes into the host cell…”
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Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes by Tsuchiya, Kohsuke, Hara, Hideki, Kawamura, Ikuo, Nomura, Takamasa, Yamamoto, Takeshi, Daim, Sylvia, Dewamitta, Sita R, Shen, Yanna, Fang, Rendong, Mitsuyama, Masao

“…Listeria monocytogenes invades the cytoplasm of macrophages and induces the activation of caspase-1 and the subsequent maturation of IL-1beta and IL-18…”
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The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation by Yang, Ruili, Xi, Chen, Sita, Dewamitta R., Sakai, Shunsuke, Tsuchiya, Kohsuke, Hara, Hideki, Shen, Yanna, Qu, Huixin, Fang, Rendong, Mitsuyama, Masao, Kawamura, Ikuo

“…Abstract Region of difference 1 (RD1) is a genomic locus in the Mycobacterium tuberculosis genome that has been shown to participate in the virulence of the…”
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Expression of the Mycobacterium tuberculosis PPE37 protein in Mycobacterium smegmatis induces low tumour necrosis factor alpha and interleukin 6 production in murine macrophages by DAIM, Sylvia, KAWAMURA, Ikuo, MITSUYAMA, Masao, TSUCHIYA, Kohsuke, HARA, Hideki, KURENUMA, Takeshi, YANNA SHEN, DEWAMITTA, Sita R, SAKAI, Shunsuke, NOMURA, Takamasa, HUIXIN QU

“…PPE37 is a member of the Mycobacterium tuberculosis proline-proline-glutamic acid (PPE) multigene family. Its expression is upregulated in bacteria that are…”
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Listeriolysin O-Dependent Bacterial Entry into the Cytoplasm Is Required for Calpain Activation and Interleukin-1 Secretion in Macrophages Infected with Listeria monocytogenes by Dewamitta, Sita R, Nomura, Takamasa, Kawamura, Ikuo, Hara, Hideki, Tsuchiya, Kohsuke, Kurenuma, Takeshi, Shen, Yanna, Daim, Sylvia, Yamamoto, Takeshi, Qu, Huixin

“…Listeriolysin O (LLO), an hly-encoded cytolysin of Listeria monocytogenes, plays an essential role in the entry of L. monocytogenes into the host cell…”
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The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1[alpha] from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation by Yang, Ruili, Xi, Chen, Sita, Dewamitta R, Sakai, Shunsuke, Tsuchiya, Kohsuke, Hara, Hideki, Shen, Yanna, Qu, Huixin, Fang, Rendong, Mitsuyama, Masao, Kawamura, Ikuo

“…Region of difference 1 (RD1) is a genomic locus in the Mycobacterium tuberculosis genome that has been shown to participate in the virulence of the bacterium,…”
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