Search Results - "Devine, Lauren"

Stimulus‐dependent modifications in astrocyte‐derived extracellular vesicle cargo regulate neuronal excitability by Datta Chaudhuri, Amrita, Dasgheyb, Raha M., DeVine, Lauren R., Bi, Honghao, Cole, Robert N., Haughey, Norman J.

“…Extracellular vesicles have now emerged as key players in cell‐to‐cell communication. This is particularly important in the central nervous system, where…”
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Improving adolescents' dietary behaviours in the school-setting: challenges and opportunities by Devine, Lauren D, Hill, Alyson J, Gallagher, Alison M

“…Adolescence is a critical time of physical, psychological and social development, and thus, optimal nutritional intakes are required during this life stage…”
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The role of N-terminal phosphorylation of DGK-θ by Barbernitz, Millie X., Devine, Lauren R., Cole, Robert N., Raben, Daniel M.

“…Diacylglycerol kinases (DGKs) are lipid kinases that mediate the phosphorylation of diacylglycerol (DAG) leading to the production of phosphatidic acid…”
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The cardiac acetyl-lysine proteome by Foster, D Brian, Liu, Ting, Rucker, Jasma, O'Meally, Robert N, Devine, Lauren R, Cole, Robert N, O'Rourke, Brian

“…In the heart, lysine acetylation has been implicated in processes ranging from transcriptional control of pathological remodeling, to cardioprotection arising…”
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Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation by Liu, Xi, Abraham, John M., Cheng, Yulan, Wang, Zhixiong, Wang, Zhe, Zhang, Guanjun, Ashktorab, Hassan, Smoot, Duane T., Cole, Robert N., Boronina, Tatiana N., DeVine, Lauren R., Talbot, C. Conover, Liu, Zhengwen, Meltzer, Stephen J.

“…MicroRNA (miR) sponges containing miR binding sequences constitute a potentially powerful molecular therapeutic strategy. Recently, naturally occurring…”
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What factors influence sustainable and healthy diet consumption? A review and synthesis of literature within the university setting and beyond by Elliott, Patrick S., Devine, Lauren D., Gibney, Eileen R., O'Sullivan, Aifric M.

“…Globally, typical dietary patterns are neither healthy nor sustainable. Recognizing the key role of dietary change in reducing noncommunicable disease risk and…”
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Methylene Blue for Vasoplegia During Extracorporeal Membrane Oxygenation Support by Ortoleva, Jamel, Roberts, Russel J., Devine, Lauren T., French, Amy, Kawabori, Masashi, Chen, Fredrick, Shelton, Kenneth, Dalia, Adam A.

“…The treatment of refractory vasodilatory shock in patients undergoing extracorporeal membrane oxygenation (ECMO) is an area in which there is minimal…”
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Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1 by Bullen, John W, Tchernyshyov, Irina, Holewinski, Ronald J, DeVine, Lauren, Wu, Fan, Venkatraman, Vidya, Kass, David L, Cole, Robert N, Van Eyk, Jennifer, Semenza, Gregg L

“…Hypoxia-inducible factor 1 (HIF-1) activates the transcription of genes encoding proteins that enable cells to adapt to reduced O2 availability. Proteins…”
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Diverse mitochondrial abnormalities in a new cellular model of TAFFAZZIN deficiency are remediated by cardiolipin-interacting small molecules by Anzmann, Arianna F., Sniezek, Olivia L., Pado, Alexandra, Busa, Veronica, Vaz, Frédéric M., Kreimer, Simion D., DeVine, Lauren R., Cole, Robert N., Le, Anne, Kirsch, Brian J., Claypool, Steven M., Vernon, Hilary J.

“…Barth syndrome (BTHS) is an X-linked disorder of mitochondrial phospholipid metabolism caused by pathogenic variants in TAFFAZIN, which results in abnormal…”
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Methylene blue for vasodilatory shock in the intensive care unit: a retrospective, observational study by Naoum, Emily E, Dalia, Adam A, Roberts, Russel J, Devine, Lauren T, Ortoleva, Jamel

“…Abstract Background Refractory vasodilatory shock is a state of uncontrolled vasodilation associated with underlying inflammation and endothelial…”
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Multiubiquitination of TRPV4 reduces channel activity independent of surface localization by Aisenberg, William H., McCray, Brett A., Sullivan, Jeremy M., Diehl, Erika, DeVine, Lauren R., Alevy, Jonathan, Bagnell, Anna M., Carr, Patrice, Donohue, Jack K., Goretzki, Benedikt, Cole, Robert N., Hellmich, Ute A., Sumner, Charlotte J.

“…Ubiquitin (Ub)-mediated regulation of plasmalemmal ion channel activity canonically occurs via stimulation of endocytosis. Whether ubiquitination can modulate…”
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Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle by Ramirez-Correa, Genaro A, Ma, Junfeng, Slawson, Chad, Zeidan, Quira, Lugo-Fagundo, Nahyr S, Xu, Mingguo, Shen, Xiaoxu, Gao, Wei Dong, Caceres, Viviane, Chakir, Khalid, DeVine, Lauren, Cole, Robert N, Marchionni, Luigi, Paolocci, Nazareno, Hart, Gerald W, Murphy, Anne M

“…Contractile dysfunction and increased deposition of O-linked β-N-acetyl-d-glucosamine (O-GlcNAc) in cardiac proteins are a hallmark of the diabetic heart…”
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Immortalized striatal precursor neurons from Huntington’s disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics by Akimov, Sergey S, Jiang, Mali, Kedaigle, Amanda J, Arbez, Nicolas, Marque, Leonard O, Eddings, Chelsy R, Ranum, Paul T, Whelan, Emma, Tang, Anthony, Wang, Ronald, DeVine, Lauren R, Talbot, Conover C, Cole, Robert N, Ratovitski, Tamara, Davidson, Beverly L, Fraenkel, Ernest, Ross, Christopher A

“…Abstract We have previously established induced pluripotent stem cell (iPSC) models of Huntington’s disease (HD), demonstrating CAG-repeat-expansion-dependent…”
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Factors that influence food choices in secondary school canteens: a qualitative study of pupil and staff perspectives by Devine, Lauren D, Gallagher, Alison M, Briggs, Stephen, Hill, Alyson J

“…Adolescence is recognised as a period of nutritional vulnerability, with evidence indicating that United Kingdom adolescents have suboptimal dietary intakes…”
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Efficacy and Safety of Immediate-Release Nifedipine in Critically Ill Patients by Seto, Stephanie L., Barra, Megan E., Hamidi, Arzo, Sin, Jonathan H., Devine, Lauren T.

“…Background: Immediate-release nifedipine (IRN) is a calcium channel blocker with potent vasodilatory and antihypertensive properties. Safety concerns led to a…”
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Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity by Barber, Casey N, Goldschmidt, Hana L, Ma, Qianqian, Devine, Lauren R, Cole, Robert N, Huganir, Richard L, Raben, Daniel M

“…Lipids and their metabolic enzymes are a critical point of regulation for the membrane curvature required to induce membrane fusion during synaptic vesicle…”
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C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease by Goodier, John L, Soares, Alisha O, Pereira, Gavin C, DeVine, Lauren R, Sanchez, Laura, Cole, Robert N, García-Pérez, Jose Luis

“…A pathogenic GGGCCC hexanucleotide expansion in the first intron/promoter region of the C9orf72 gene is the most common mutation associated with amyotrophic…”
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Plasma proteomic analysis on neuropathic pain in idiopathic peripheral neuropathy patients by Doormaal, Perry T. C., Thomas, Simone, Ajroud‐Driss, Senda, Cole, Robert N., DeVine, Lauren R., Dimachkie, Mazen M., Geisler, Stefanie, Freeman, Roy, Simpson, David M., Singleton, J. Robinson, Smith, A. Gordon, Stino, Amro, Höke, Ahmet

“…Background and Aims Why only half of the idiopathic peripheral neuropathy (IPN) patients develop neuropathic pain remains unknown. By conducting a proteomics…”
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The plasma proteome identifies expected and novel proteins correlated with micronutrient status in undernourished Nepalese children by Cole, Robert N, Ruczinski, Ingo, Schulze, Kerry, Christian, Parul, Herbrich, Shelley, Wu, Lee, Devine, Lauren R, O'Meally, Robert N, Shrestha, Sudeep, Boronina, Tatiana N, Yager, James D, Groopman, John, West, Jr, Keith P

“…Micronutrient deficiencies are common in undernourished societies yet remain inadequately assessed due to the complexity and costs of existing assays. A plasma…”
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Human Breast Milk Enhances Intestinal Mucosal Barrier Function and Innate Immunity in a Healthy Pediatric Human Enteroid Model by Noel, Gaelle, In, Julie G, Lemme-Dumit, Jose M, DeVine, Lauren R, Cole, Robert N, Guerrerio, Anthony L, Campbell, James D, Kovbasnjuk, Olga, Pasetti, Marcela F

“…Breastfeeding has been associated with long lasting health benefits. Nutrients and bioactive components of human breast milk promote cell growth, immune…”
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