Search Results - "Devine, Deirdre A."

Influence of saliva on the oral microbiota by Marsh, Philip D., Do, Thuy, Beighton, David, Devine, Deirdre A.

“…Saliva plays a major role in determining the composition and activity of the oral microbiota, via a variety of mechanisms. Molecules, mainly from saliva, form…”
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Ecological approaches to oral biofilms: control without killing by Marsh, Phil D, Head, David A, Devine, Deirdre A

“…Humans have co-evolved with micro-organisms and have a symbiotic or mutualistic relationship with their resident microbiome. As at other body surfaces, the…”
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Periodontal disease and periodontal bacteria as triggers for rheumatoid arthritis by Cheng, Zijian, Meade, Josephine, Mankia, Kulveer, Emery, Paul, Devine, Deirdre A.

“…There is an epidemiological association between periodontitis and rheumatoid arthritis (RA), which is hypothesised to lead to enhanced generation of RA-related…”
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How is the development of dental biofilms influenced by the host? by Marsh, Philip D., Devine, Deirdre A.

“…Marsh PD, Devine DA. How is the development of dental biofilms influenced by the host? J Clin Periodontol 2011; 38 (Suppl. 11): 28–35. doi:…”
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In silico modelling to differentiate the contribution of sugar frequency versus total amount in driving biofilm dysbiosis in dental caries by Head, David, A. Devine, Deirdre, Marsh, P. D.

“…Dental caries is the most prevalent infection globally and a substantial economic burden in developed countries. Dietary sugars are the main risk factor, and…”
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Cation complexation by mucoid Pseudomonas aeruginosa extracellular polysaccharide by Hills, Oliver J, Smith, James, Scott, Andrew J, Devine, Deirdre A, Chappell, Helen F

“…Mucoid Pseudomonas aeruginosa is a prevalent cystic fibrosis (CF) lung colonizer, producing an extracellular matrix (ECM) composed predominantly of the…”
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Atomic-scale interactions between quorum sensing autoinducer molecules and the mucoid P. aeruginosa exopolysaccharide matrix by Hills, Oliver J., Yong, Chin W., Scott, Andrew J., Devine, Deirdre A., Smith, James, Chappell, Helen F.

“…Mucoid Pseudomonas aeruginosa is a prevalent cystic fibrosis (CF) lung coloniser whose chronicity is associated with the formation of cation cross-linked…”
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Modulation of host responses by oral commensal bacteria by Devine, Deirdre A, Marsh, Philip D, Meade, Josephine

“…Immunomodulatory commensal bacteria are proposed to be essential for maintaining healthy tissues, having multiple roles including priming immune responses to…”
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Optimization of conditions for in vitro modeling of subgingival normobiosis and dysbiosis by Baraniya, Divyashri, Do, Thuy, Chen, Tsute, Albandar, Jasim M, Chialastri, Susan M, Devine, Deirdre A, Marsh, Philip D, Al-Hebshi, Nezar N

“…Modeling subgingival microbiome in health and disease is key to identifying the drivers of dysbiosis and to studying microbiome modulation. Here, we optimize…”
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Prevalence of Periodontal Disease and Periodontopathic Bacteria in Anti-Cyclic Citrullinated Protein Antibody-Positive At-Risk Adults Without Arthritis by Mankia, Kulveer, Cheng, Zijian, Do, Thuy, Hunt, Laura, Meade, Josephine, Kang, Jing, Clerehugh, Val, Speirs, Alastair, Tugnait, Aradhna, Hensor, Elizabeth M A, Nam, Jackie L, Devine, Deirdre A, Emery, Paul

“…The prevalence of periodontitis is increased in patients with rheumatoid arthritis (RA) and periodontopathic bacteria can citrullinate proteins. Periodontitis…”
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Commensal Streptococcus salivarius K12 Downregulates the Innate Immune Responses of Human Epithelial Cells and Promotes Host-Microbe Homeostasis by Cosseau, Celine, Devine, Deirdre A, Dullaghan, Edie, Gardy, Jennifer L, Chikatamarla, Avinash, Gellatly, Shaan, Yu, Lorraine L, Pistolic, Jelena, Falsafi, Reza, Tagg, John, Hancock, Robert E.W

“…Streptococcus salivarius is an early colonizer of human oral and nasopharyngeal epithelia, and strain K12 has reported probiotic effects. An emerging paradigm…”
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Non-lethal control of the cariogenic potential of an agent-based model for dental plaque by Head, David A, Marsh, Phil D, Devine, Deirdre A

“…Dental caries or tooth decay is a prevalent global disease whose causative agent is the oral biofilm known as plaque. According to the ecological plaque…”
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Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis by Costeira, Ricardo, Aduse-Opoku, Joseph, Vernon, Jon J, Rodriguez-Algarra, Francisco, Joseph, Susan, Devine, Deirdre A, Marsh, Philip D, Rakyan, Vardhman, Curtis, Michael A, Bell, Jordana T

“…Periodontal disease is a chronic inflammatory disease in which the oral pathogen plays an important role. expresses virulence determinants in response to…”
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Prospects for the development of probiotics and prebiotics for oral applications by Devine, Deirdre A., Marsh, Philip D.

“…There has been a paradigm shift towards an ecological and microbial community-based approach to understanding oral diseases. This has significant implications…”
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Prospects of oral disease control in the future - an opinion by Marsh, Philip D., Head, David A., Devine, Deirdre A.

“…The mouth supports a diverse microbiota which provides major benefits to the host. On occasions, this symbiotic relationship breaks down (dysbiosis), and…”
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Dental plaque biofilms: communities, conflict and control by Marsh, Philip D., Moter, Annette, Devine, Deirdre A.

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The effect of cocoa polyphenols on the growth, metabolism, and biofilm formation by Streptococcus mutans and Streptococcus sanguinis by Percival, Rimondia S., Devine, Deirdre A., Duggal, Monty S., Chartron, Sylvie, Marsh, Philip D.

“…The aim of this study was to determine if cocoa polyphenols could interfere with biofilm formation by Streptococcus mutans or Streptococcus sanguinis, and…”
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Dental plaque as a biofilm and a microbial community—Implications for treatment by Marsh, Philip D., Head, David A., Devine, Deirdre A.

“…The mouth supports a diverse microbiota which exists as structurally-organised biofilms on mucosal and dental surfaces. The oral microbiota provides major…”
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Molecular basis for avirulence of spontaneous variants of Porphyromonas gingivalis: Genomic analysis of strains W50, BE1 and BR1 by Aduse‐Opoku, Joseph, Joseph, Susan, Devine, Deirdre A, Marsh, Philip D, Curtis, Michael A

“…The periodontal pathogen Porphyromonas gingivalis is genetically heterogeneous. However, the spontaneous generation of phenotypically different sub‐strains has…”
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Immunomodulatory streptococci that inhibit CXCL8 secretion and NFκB activation are common members of the oral microbiota by Myers, Sarah, Do, Thuy, Meade, Josephine L, Tugnait, Aradhna, Vernon, Jon J, Pistolic, Jelena, Hancock, Robert E W, Marsh, Philip D, Trivedi, Harsh M, Chen, Dandan, Devine, Deirdre A

“…Oral tissues are generally homeostatic despite exposure to many potential inflammatory agents including the resident microbiota. This requires the balancing of…”
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