Search Results - "Deveney, Ramona"

Overexpression of BHLHB1 (OLIG 2) Causes Precursor T-Cell Lymphoblastic Lymphoma/Leukemia (pre-T LBL) in the Presence of LMO1 Overexpression by Lin, Yingwei, Deveney, Ramona, Aplan, Peter D.

“…The human BHLHB1 (basic domain, helix-loop-helix protein, class B, 1; also known as OLIG 2) was initially cloned by virtue of its activation in pre-T…”
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OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1 by LIN, Ying-Wei, DEVENEY, Ramona, BARBARA, Mary, ISCOVE, Norman N, NIMER, Stephen D, SLAPE, Christopher, APLAN, Peter D

“…OLIG2 (originally designated BHLHB1) encodes a transcription factor that contains the basic helix-loop-helix motif. Although expression of OLIG2 is normally…”
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Insertion of MLL sequences into chromosome band 5q31 results in an MLL-AF5Q31 fusion and is a rare but recurrent abnormality associated with infant leukemia by Deveney, Ramona, Chervinsky, David S., Jani-Sait, Sheila N., Grossi, Mauro, Aplan, Peter D.

“…MLL gene rearrangements leading to production of MLL fusion proteins are commonly detected in infant leukemia patients; the most common MLL fusion associated…”
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