Search Results - "Developmental dynamics"

Epithelial–mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease by Jolly, Mohit Kumar, Ward, Chris, Eapen, Mathew Suji, Myers, Stephen, Hallgren, Oskar, Levine, Herbert, Sohal, Sukhwinder Singh

“…Epithelial–mesenchymal transition (EMT) plays key roles during lung development and many lung diseases such as chronic obstructive pulmonary disease (COPD),…”
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Making and shaping endochondral and intramembranous bones by Galea, Gabriel L., Zein, Mohamed R., Allen, Steven, Francis‐West, Philippa

“…Skeletal elements have a diverse range of shapes and sizes specialized to their various roles including protecting internal organs, locomotion, feeding,…”
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Epithelial‐to‐mesenchymal transition in cutaneous wound healing: Where we are and where we are heading by Haensel, Daniel, Dai, Xing

“…Cutaneous wound healing occurs in distinct yet overlapping steps with the end goal of reforming a stratified epithelium to restore epidermal barrier function…”
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ReMAPping the microtubule landscape: How phosphorylation dictates the activities of microtubule‐associated proteins by Ramkumar, Amrita, Jong, Brigette Y., Ori‐McKenney, Kassandra M.

“…Classical microtubule‐associated proteins (MAPs) were originally identified based on their co‐purification with microtubules assembled from mammalian brain…”
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Heart function and hemodynamic analysis for zebrafish embryos by Yalcin, Huseyin C., Amindari, Armin, Butcher, Jonathan T., Althani, Asma, Yacoub, Magdi

“…The Zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic…”
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Endothelial‐to‐mesenchymal transition in cardiovascular diseases: Developmental signaling pathways gone awry by Sánchez‐Duffhues, Gonzalo, García de Vinuesa, Amaya, Dijke, Peter

“…The process named endothelial‐to‐mesenchymal transition (EndMT) was observed for the first time during the development of the chicken embryo several decades…”
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Achondroplasia: Development, pathogenesis, and therapy by Ornitz, David M., Legeai‐Mallet, Laurence

“…Autosomal dominant mutations in fibroblast growth factor receptor 3 (FGFR3) cause achondroplasia (Ach), the most common form of dwarfism in humans, and related…”
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Extracellular matrix bioscaffolds in tissue remodeling and morphogenesis by Swinehart, Ilea T., Badylak, Stephen F.

“…During normal morphogenesis the extracellular matrix (ECM) influences cell motility, proliferation, apoptosis, and differentiation. Tissue engineers have…”
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Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain by Khacho, Mireille, Slack, Ruth S.

“…Mitochondria are classically known to be the cellular energy producers, but a renewed appreciation for these organelles has developed with the accumulating…”
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Regulation of skeletal muscle stem cells by fibroblast growth factors by Pawlikowski, Bradley, Vogler, Thomas Orion, Gadek, Katherine, Olwin, Bradley B.

“…Fibroblast growth factors (FGFs) are essential for self‐renewal of skeletal muscle stem cells (satellite cells) and required for maintenance and repair of…”
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The shape of things to come: Topological data analysis and biology, from molecules to organisms by Amézquita, Erik J., Quigley, Michelle Y., Ophelders, Tim, Munch, Elizabeth, Chitwood, Daniel H.

“…Shape is data and data is shape. Biologists are accustomed to thinking about how the shape of biomolecules, cells, tissues, and organisms arise from the…”
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Epithelial‐mesenchymal Transition and Cancer Stem Cells: At the Crossroads of Differentiation and Dedifferentiation by Wang, Hanmin, Unternaehrer, Juli J.

“…In this review, we explore the connections between epithelial‐mesenchymal transition (EMT) and differentiation status. EMTs in development have been described…”
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Hypermobile Ehlers‐Danlos syndromes: Complex phenotypes, challenging diagnoses, and poorly understood causes by Gensemer, Cortney, Burks, Randall, Kautz, Steven, Judge, Daniel P., Lavallee, Mark, Norris, Russell A.

“…The Ehlers‐Danlos syndromes (EDS) are a group of heritable, connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and…”
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Maternal immune activation in neurodevelopmental disorders by Solek, Cynthia M., Farooqi, Nasr, Verly, Myriam, Lim, Tony K., Ruthazer, Edward S.

“…Converging lines of evidence from basic science and clinical studies suggest a relationship between maternal immune activation (MIA) and neurodevelopmental…”
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Applications of Human Brain Organoids to Clinical Problems by Chen, H. Isaac, Song, Hongjun, Ming, Guo‐li

“…Brain organoids are an exciting new technology with the potential to significantly change how diseases of the brain are understood and treated. These…”
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BMP9 and BMP10: Two close vascular quiescence partners that stand out by Desroches‐Castan, Agnès, Tillet, Emmanuelle, Bouvard, Claire, Bailly, Sabine

“…Bone morphogenetic proteins (BMPs) are dimeric transforming growth factor ß (TGFß) family cytokines that were first described in bone and cartilage formation…”
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TGF‐β superfamily co‐receptors in cancer by Pawlak, John B., Blobe, Gerard C.

“…Transforming growth factor‐β (TGF‐β) superfamily signaling via their cognate receptors is frequently modified by TGF‐β superfamily co‐receptors. Signaling…”
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Epithelial–mesenchymal plasticity and circulating tumor cells: Travel companions to metastases by Francart, Marie‐Emilie, Lambert, Justine, Vanwynsberghe, Aline M., Thompson, Erik W., Bourcy, Morgane, Polette, Myriam, Gilles, Christine

“…Epithelial–mesenchymal transitions (EMTs) associated with metastatic progression may contribute to the generation of hybrid phenotypes capable of plasticity…”
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Prospects for new lung cancer treatments that target EMT signaling by Otsuki, Yuji, Saya, Hideyuki, Arima, Yoshimi

“…Lung cancer is the most common cancer worldwide. Treatment options for lung cancer include surgery, radiation therapy, chemotherapy, molecularly targeted…”
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Poly peak parser: Method and software for identification of unknown indels using sanger sequencing of polymerase chain reaction products by Hill, Jonathon T., Demarest, Bradley L., Bisgrove, Brent W., Su, Yi‐Chu, Smith, Megan, Yost, H. Joseph

“…Background: Genome editing techniques, including ZFN, TALEN, and CRISPR, have created a need to rapidly screen many F1 individuals to identify carriers of…”
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