Search Results - "Devarajan, Sriraman"
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Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation
Published in PloS one (22-07-2015)“…The role of IL-6R/IL-6 axis in metabolic inflammation remains controversial. We determined the changes in adipose tissue expression of IL-6R and IL-6 in obese,…”
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2
Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes
Published in Scientific reports (30-06-2020)“…Spexin is a novel neuropeptide playing an emerging role in metabolic diseases such as obesity and diabetes via involvement in energy homeostasis and food…”
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3
Sputum production and salivary microbiome in COVID-19 patients reveals oral-lung axis
Published in PloS one (25-07-2024)“…SARS-CoV-2, a severe respiratory disease primarily targeting the lungs, was the leading cause of death worldwide during the pandemic. Understanding the…”
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Circulating ANGPTL8/Betatrophin Is Increased in Obesity and Reduced after Exercise Training
Published in PloS one (19-01-2016)“…ANGPTL8 is a liver and adipose tissue produced protein that regulates the level of triglyceride in plasma as well as glucose homeostasis. This study was…”
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5
Clinical characteristics of coronavirus disease 2019 (COVID-19) patients in Kuwait
Published in PloS one (20-11-2020)“…This is a retrospective single-center study of 417 consecutive patients with coronavirus disease 2019 (COVID-19) admitted to Jaber Al-Ahmad Hospital in Kuwait…”
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Fetuin-A levels are increased in the adipose tissue of diabetic obese humans but not in circulation
Published in Lipids in health and disease (22-12-2018)“…The hepatokine fetuin-A is linked to obesity and type 2 diabetes, but its presence and expression in adipose tissue remain unclear. In this study, we aimed to…”
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Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension
Published in Lipids in health and disease (01-03-2018)“…Hypertension is a risk factor for both cardiovascular diseases (CVDs) and type 2 diabetes (T2D). Angiopoietin-like proteins (ANGPTLs), mainly ANGPTL3, ANGPTL4…”
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Optical coherence tomography segmentation analysis in relapsing remitting versus progressive multiple sclerosis
Published in PloS one (13-02-2017)“…Optical coherence tomography (OCT) with retinal segmentation analysis is a valuable tool in assessing axonal loss and neuro-degeneration in multiple sclerosis…”
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Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D
Published in Lipids in health and disease (13-10-2016)“…Hypertriglyceridemia is associated with increased risk for cardiovascular diseases and type 2 diabetes (T2D). Angiopoietin like proteins particularly 3, 4 and…”
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Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy
Published in International journal of molecular sciences (01-09-2023)“…Diabetic nephropathy (DN) is a complicated condition related to type 2 diabetes mellitus (T2D). ANGPTL8 is a hepatic protein highlighted as a risk factor for…”
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Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise
Published in PloS one (06-03-2017)“…ANGPTL7 is a member of the Angiopoietin-like (ANGPTL) protein family that is composed of eight proteins (1-8). Increasing evidence is associating ANGPTL…”
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Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise
Published in Frontiers in endocrinology (Lausanne) (06-11-2019)“…Urocortin3 (UCN3) regulates metabolic functions and is involved in cellular stress response. Although UCN3 is expressed in human adipose tissue, the…”
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13
Association between Frequency of Toothbrushing and Metabolic Syndrome among Adolescents: A 5-Year Follow-Up Study
Published in International journal of environmental research and public health (03-01-2022)“…This study longitudinally examines the relationship between the frequency of toothbrushing and the development of selected components of metabolic syndrome…”
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14
Association of significantly elevated plasma levels of NGAL and IGFBP4 in patients with diabetic nephropathy
Published in BMC nephrology (11-02-2022)“…Diabetic nephropathy (DN) is a type of progressive kidney disease affecting approximately 40% of patients with diabetes. Current DN diagnostic criteria…”
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Potential Role of N-Cadherin in Diagnosis and Prognosis of Diabetic Nephropathy
Published in Frontiers in endocrinology (Lausanne) (31-05-2022)“…Diabetic nephropathy (DN) is a serious complication of diabetes affecting about half the people with diabetes and the leading cause of end stage renal disease…”
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Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea
Published in Frontiers in endocrinology (Lausanne) (13-11-2018)“…Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is…”
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Angiopoietin-2 and Angiopoietin-like Proteins with a Prospective Role in Predicting Diabetic Nephropathy
Published in Biomedicines (01-05-2024)“…Angiopoietins are crucial growth factors for maintaining a healthy, functional endothelium. Patients with type 2 diabetes (T2D) exhibit significant levels of…”
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The Rise of IGFBP4 in People with Obstructive Sleep Apnea and Multilevel Sleep Surgery Recovers Its Basal Levels
Published in Disease markers (2021)“…IGFBP4 is the smallest member of the insulin-like growth factor binding protein family (IGFBP). It is a hepatic protein that plays a role in modulating the…”
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The relationship between sleep and salivary and serum inflammatory biomarkers in adolescents
Published in Frontiers in medicine (26-05-2023)“…Poor sleep behavior can trigger an inflammatory response and contribute to the development of inflammatory diseases. Cytokines can act as indicators of…”
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Association between risk of obstructive sleep apnea severity and risk of severe COVID-19 symptoms: insights from salivary and serum cytokines
Published in Frontiers in public health (21-02-2024)“…Obstructive sleep apnea (OSA) can adversely affect the immune response through clinical factors such as hypoxia, inflammation, and sleep disturbance. Since…”
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