Search Results - "Devanand, D. P"

Association of APOE e2 genotype with Alzheimer’s and non-Alzheimer’s neurodegenerative pathologies by Goldberg, Terry E., Huey, Edward D., Devanand, D. P.

“…The apolipoprotein E (APOE) gene contains both the major common risk variant for late onset Alzheimer’s disease (AD), e4, and the major neuroprotective…”
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Effect of Citalopram on Agitation in Alzheimer Disease: The CitAD Randomized Clinical Trial by Porsteinsson, Anton P, Drye, Lea T, Pollock, Bruce G, Devanand, D. P, Frangakis, Constantine, Ismail, Zahinoor, Marano, Christopher, Meinert, Curtis L, Mintzer, Jacobo E, Munro, Cynthia A, Pelton, Gregory, Rabins, Peter V, Rosenberg, Paul B, Schneider, Lon S, Shade, David M, Weintraub, Daniel, Yesavage, Jerome, Lyketsos, Constantine G

“…IMPORTANCE Agitation is common, persistent, and associated with adverse consequences for patients with Alzheimer disease. Pharmacological treatment options,…”
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Olfactory Identification Deficits, Cognitive Decline, and Dementia in Older Adults by Devanand, D.P., M.D

“…Several recently developed biomarkers of Alzheimer disease (AD) are invasive, expensive, and difficult to obtain in most clinical settings. Olfactory…”
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Resting-state functional connectivity changes in older adults with sleep disturbance and the role of amyloid burden by Kim, Hyun, Zhu, Xi, Zhao, Yiming, Bell, Sophie A., Gehrman, Philip R., Cohen, Daniel, Devanand, D. P., Goldberg, Terry E., Lee, Seonjoo

“…Sleep and related disorders could lead to changes in various brain networks, but little is known about the role of amyloid β (Aβ) burden—a key Alzheimer’s…”
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Relapse Risk after Discontinuation of Risperidone in Alzheimer's Disease by Devanand, D.P, Mintzer, Jacobo, Schultz, Susan K, Andrews, Howard F, Sultzer, David L, de la Pena, Danilo, Gupta, Sanjay, Colon, Sylvia, Schimming, Corbett, Pelton, Gregory H, Levin, Bruce

“…In a study of patients with Alzheimer's disease and associated psychosis or agitation that had responded to risperidone, the risk of relapse was greater among…”
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Associations between olfactory dysfunction and cognition: a scoping review by Jacobson, Patricia T., Vilarello, Brandon J., Tervo, Jeremy P., Waring, Nicholas A., Gudis, David A., Goldberg, Terry E., Devanand, D. P., Overdevest, Jonathan B.

“…Introduction Strong evidence suggests that olfactory dysfunction (OD) can predict additional neurocognitive decline in neurodegenerative conditions such as…”
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Hippocampal and entorhinal atrophy in mild cognitive impairment : Prediction of Alzheimer disease by DEVANAND, D. P, PRADHABAN, G, STERN, Y, TABERT, M. H, DE LEON, M. J, LIU, X, KHANDJI, A, DE SANTI, S, SEGAL, S, RUSINEK, H, PELTON, G. H, HONIG, L. S, MAYEUX, R

“…To evaluate the utility of MRI hippocampal and entorhinal cortex atrophy in predicting conversion from mild cognitive impairment (MCI) to Alzheimer disease…”
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Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment by Javitt, Daniel C, Martinez, Antigona, Sehatpour, Pejman, Beloborodova, Anna, Habeck, Christian, Gazes, Yunglin, Bermudez, Dalton, Razlighi, Qolamreza R, Devanand, D P, Stern, Yaakov

“…Amyloid deposition is a primary predictor of Alzheimer's disease (AD) and related neurodegenerative disorders. Retinal changes involving the structure and…”
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Dysthymic disorder in the elderly population by Devanand, D P

“…The diagnosis of dysthymic disorder was created in DSM-III and maintained in DSM-IV to describe a depressive syndrome of mild to moderate severity of at least…”
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A 10-item smell identification scale related to risk for Alzheimer's disease by Tabert, Matthias H., Liu, Xinhua, Doty, Richard L., Serby, Michael, Zamora, Diana, Pelton, Gregory H., Marder, Karen, Albers, Mark W., Stern, Yaakov, Devanand, D. P.

“…University of Pennsylvania Smell Identification Test data from control subjects (n = 63), patients with mild cognitive impairment (n = 147), and patients with…”
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Brain Amyloid Deposition and Longitudinal Cognitive Decline in Nondemented Older Subjects: Results from a Multi-Ethnic Population by Gu, Yian, Razlighi, Qolamreza R, Zahodne, Laura B, Janicki, Sarah C, Ichise, Masanori, Manly, Jennifer J, Devanand, D P, Brickman, Adam M, Schupf, Nicole, Mayeux, Richard, Stern, Yaakov

“…We aimed to whether the abnormally high amyloid-β (Aβ) level in the brain among apparently healthy elders is related with subtle cognitive deficits and/or…”
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Antiviral therapy: Valacyclovir Treatment of Alzheimer’s Disease (VALAD) Trial: protocol for a randomised, double-blind,placebo-controlled, treatment trial by Devanand, D P, Andrews, Howard, Kreisl, William C, Razlighi, Qolamreza, Gershon, Anne, Stern, Yaakov, Mintz, Akiva, Wisniewski, Thomas, Acosta, Edward, Pollina, Julianna, Katsikoumbas, Mariasofia, Bell, Karen L, Pelton, Gregory H, Deliyannides, Deborah, Prasad, K M, Huey, Edward D

“…IntroductionAfter infection, herpes simplex virus-1 (HSV1) becomes latent in the trigeminal ganglion and can enter the brain via retrograde axonal transport…”
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Advancing Computerized Cognitive Training for MCI and Alzheimer's Disease in a Pandemic and Post-pandemic World by Bodner, Kaylee A, Goldberg, Terry E, Devanand, D P, Doraiswamy, P Murali

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Comparative mortality risks of antipsychotic medications in community-dwelling older adults by Gerhard, T., Huybrechts, K., Olfson, M., Schneeweiss, S., Bobo, W. V., Doraiswamy, P. M., Devanand, D. P., Lucas, J. A., Huang, C., Malka, E. S., Levin, R., Crystal, S.

“…All antipsychotic medications carry warnings of increased mortality for older adults, but little is known about comparative mortality risks between individual…”
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Olfactory identification deficits and MCI in a multi-ethnic elderly community sample by Devanand, D.P, Tabert, Matthias H, Cuasay, Katrina, Manly, Jennifer J, Schupf, Nicole, Brickman, Adam M, Andrews, Howard, Brown, Truman R, DeCarli, Charles, Mayeux, Richard

“…Abstract Odor identification deficits occur in Alzheimer’s disease (AD) and mild cognitive impairment (MCI), and predict clinical conversion from MCI to AD. In…”
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Functional deficits in patients with mild cognitive impairment: Prediction of AD by TABERT, M. H, ALBERT, S. M, BORUKHOVA-MILOV, L, CAMACHO, Y, PELTON, G, LIU, X, STERN, Y, DEVANAND, D. P

“…To evaluate the predictive utility of self-reported and informant-reported functional deficits in patients with mild cognitive impairment (MCI) for the…”
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Impaired Identification of Specific Odors and Cognition in Older Adults by Devanand, D.P.

“…Devanand discusses the impaired identification of specific odors and cognition in older adults. He says that impaired odor identification is a well-replicated…”
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Olfaction and neurocognition after COVID-19: a scoping review by Vilarello, Brandon J, Jacobson, Patricia T, Tervo, Jeremy P, Waring, Nicholas A, Gudis, David A, Goldberg, Terry E, Devanand, D P, Overdevest, Jonathan B

“…COVID-19 induces both acute and chronic neurological changes. Existing evidence suggests that chemosensory changes, particularly olfactory loss, may reflect…”
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A 6-month, randomized, double-blind, placebo-controlled pilot discontinuation trial following response to haloperidol treatment of psychosis and agitation in Alzheimer's disease by Devanand, D.P., Pelton, Gregory H., Cunqueiro, Karine, Sackeim, Harold A., Marder, Karen

“…Objective In patients with Alzheimer's disease (AD) with psychosis or agitation that respond to haloperidol treatment, to evaluate the risk of relapse…”
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Effects of Citalopram on Neuropsychiatric Symptoms in Alzheimer’s Dementia: Evidence From the CitAD Study by Leonpacher, Anne K., Peters, Matthew E., Drye, Lea T., Makino, Kelly M., Newell, Jeffery A., Devanand, D.P., Frangakis, Constantine, Munro, Cynthia A., Mintzer, Jacobo E., Pollock, Bruce G., Rosenberg, Paul B., Schneider, Lon S., Shade, David M., Weintraub, Daniel, Yesavage, Jerome, Lyketsos, Constantine G., Porsteinsson, Anton P.

“…Objective:Citalopram has been shown to improve agitation in patients with Alzheimer’s disease. The authors evaluated whether other neuropsychiatric symptoms…”
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