Search Results - "Devamani, Titu"

Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases by Devamani, Titu, Rauwerdink, Alissa M, Lunzer, Mark, Jones, Bryan J, Mooney, Joanna L, Tan, Maxilmilien Alaric O, Zhang, Zhi-Jun, Xu, Jian-He, Dean, Antony M, Kazlauskas, Romas J

“…Catalytic promiscuity is a useful, but accidental, enzyme property, so finding catalytically promiscuous enzymes in nature is inefficient. Some ancestral…”
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Enantiomerically pure allylic alcohols: preparation by Candida parapsilosis ATCC 7330 mediated deracemisation by Titu, Devamani, Chadha, Anju

“…Biocatalytic deracemisation of racemic allylic alcohols by whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the ( R)-enantiomers in…”
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A thermostable transketolase evolved for aliphatic aldehyde acceptors by Yi, Dong, Saravanan, Thangavelu, Devamani, Titu, Charmantray, Franck, Hecquet, Laurence, Fessner, Wolf-Dieter

“…Directed evolution of the thermostable transketolase from Geobacillus stearothermophilus based on a pH-based colorimetric screening of smart libraries yielded…”
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Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism by Ma, Ning, Lippert, Lisa G, Devamani, Titu, Levy, Benjamin, Lee, Sangbae, Sandhu, Manbir, Vaidehi, Nagarajan, Sivaramakrishnan, Sivaraj

“…Protein kinases achieve substrate selective phosphorylation through their conformational flexibility and dynamic interaction with the substrate. Designing…”
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Distinct structural mechanisms determine substrate affinity and kinase activity of protein kinase Cα by Lee, Sangbae, Devamani, Titu, Song, Hyun Deok, Sandhu, Manbir, Larsen, Adrien, Sommese, Ruth, Jain, Abhinandan, Vaidehi, Nagarajan, Sivaramakrishnan, Sivaraj

“…Protein kinase Cα (PKCα) belongs to the family of AGC kinases that phosphorylate multiple peptide substrates. Although the consensus sequence motif has been…”
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The PKC inhibitor BimI functions as a bi‐topic ligand that toggles a conserved allosteric switch to drive potent kinase inhibition by ma, ning, Lee, Sangbae, Devamani, Titu, Sandhu, Manbir, Sommese, Ruth, Sivaramakrishnan, Sivaraj, Vaidehi, Nagarajan

“…ATP‐competitive small‐molecule kinase inhibitors (SMKIs) are viewed primarily from the lens of tight and specific binding to the conserved catalytic domain…”
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Mechanism of Allosteric Regulation of Substrate Specificity in Protein Kinase C by Vaidehi, Nagarajan, Deok Song, Hyun, Devamani, Titu, Sommese, Ruth, Sivaramakrishnan, Sivaraj

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Evolution of a Catalytic Mechanism by Rauwerdink, Alissa, Lunzer, Mark, Devamani, Titu, Jones, Bryan, Mooney, Joanna, Zhang, Zhi-Jun, Xu, Jian-He, Kazlauskas, Romas J, Dean, Antony M

“…The means by which superfamilies of specialized enzymes arise by gene duplication and functional divergence are poorly understood. The escape from adaptive…”
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Thermostable Transketolase from Geobacillus stearothermophilus: Characterization and Catalytic Properties by Abdoul-Zabar, Juliane, Sorel, Isabelle, Hélaine, Virgil, Charmantray, Franck, Devamani, Titu, Yi, Dong, de Berardinis, Véronique, Louis, Dominique, Marlière, Philippe, Fessner, Wolf-Dieter, Hecquet, Laurence

“…Here we have characterized the first transketolase (TK) from a thermophilic microorganism, Geobacillus stearothermophilus, which was expressed from a synthetic…”
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Engineering a Thermostable Transketolase for Unnatural Conversion of (2S)-Hydroxyaldehydes by Abdoul Zabar, Juliane, Lorillière, Marion, Yi, Dong, Saravanan, Thangavelu, Devamani, Titu, Nauton, Lionel, Charmantray, Franck, Hélaine, Virgil, Fessner, Wolf-Dieter, Hecquet, Laurence

“…Transketolase (TK) from various origins (including Escherichia coli and yeast) has been described to be fully enantiomer specific for (2R)‐hydroxyaldehyde…”
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A pH-Based High-Throughput Assay for Transketolase: Fingerprinting of Substrate Tolerance and Quantitative Kinetics by Yi, Dong, Devamani, Titu, Abdoul-Zabar, Juliane, Charmantray, Franck, Helaine, Virgil, Hecquet, Laurence, Fessner, Wolf-Dieter

“…A pH‐based high‐throughput assay method has been developed for the rapid and reliable measurement of transketolase (TK) activity. The method is based on the…”
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A Novel Method for Monitoring the Transesterification Reaction of Oil in Biodiesel Production by Estimation of Glycerol by Reddy, Sabbasani Rajasekhara, Titu, Devamani, Chadha, Anju

“…A quantitative method is reported for the estimation of glycerol during transesterification of oil to form biodiesel. The reagent used to derivatize glycerol…”
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Erratum to: A Novel Method for Monitoring the Transesterification Reaction of Oil in Biodiesel Production by Estimation of Glycerol by Reddy, Sabbasani Rajasekhara, Titu, Devamani, Chadha, Anju

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Engineering a Thermostable Transketolase for Unnatural Conversion of (2S)-Hydroxyaldehyde by Abdoul-Zabar, Juliane, Lorillière, Marion, Yi, Dong, Saravanan, Thangavelu, Devamani, Titu, Nauton, Lionel, Charmantray, Franck, Hélaine, Virgil, Fessner, Wolf-Dieter, Hecquet, Laurence

“…Transketolase (TK) from various origins (including Escherichia coli and yeast) has been described to be fully enantiomer specific for (2R)-hydroxyaldehyde…”
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