Search Results - "Deutsch, Assaf"
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A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids
Published in Biomaterials (01-11-2010)“…Abstract Multicellular spheroid models have been recognized as superior to monolayer cell cultures in antitumor drug screening, but their commercial adaptation…”
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Dynamic Ratiometric Imaging of Cytosolic Free Ca2+ in Skeletal Muscle Cells Using 340/385-nm Light-Emitting Diode Illuminators
Published in IEEE photonics journal (01-12-2018)“…Calcium-sensitive fluorescent indicators fall broadly into two categories, ratiometric (dual-wavelength) or single-wavelength indicators based on their…”
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Intracellular esterase activity in living cells may distinguish between metastatic and tumor-free lymph nodes
Published in Clinical & experimental metastasis (01-05-2008)“…Background One of the major clinical problems in breast cancer detection is the relatively high incidence of occult lymph node metastases undetectable by…”
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The individual-cell-based cryo-chip for the cryopreservation, manipulation and observation of spatially identifiable cells. I: methodology
Published in BMC Cell Biology (07-07-2010)“…Cryopreservation is the only widely applicable method of storing vital cells for nearly unlimited periods of time. Successful cryopreservation is essential for…”
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Functional analysis of individual cells and microenvironment of breast cancer‐draining lymph nodes
Published in Cancer science (01-05-2008)“…The development of distant metastases is the major cause of death in breast cancer (BC). In many BC cases, metastases are present in patients with no…”
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A novel miniature cell retainer for correlative high-content analysis of individual untethered non-adherent cells
Published in Lab on a chip (01-01-2006)“…The importance of research involving non-adherent cell lines, primary cells and blood cells is generally undisputed. However, the task of investigating the…”
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Dynamic Ratiometric Imaging of Cytosolic Free Ca 2+ in Skeletal Muscle Cells Using 340/385-nm Light-Emitting Diode Illuminators
Published in IEEE photonics journal (01-12-2018)Get full text
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Polymer live-cell array for real-time kinetic imaging of immune cells
Published in Biomaterials (01-06-2010)“…Abstract Direct quantitative experimental investigations of the function of lymphocytes and other immune cells are challenging due to the cell mobility and the…”
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The individual-cell-based cryo-chip for the cryopreservation, manipulation and observation of spatially identifiable cells. II: functional activity of cryopreserved cells
Published in BMC cell biology (25-10-2010)“…The cryopreservation and thawing processes are known to induce many deleterious effects in cells and might be detrimental to several cell types. There is an…”
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Mitochondrial function and tissue vitality: bench-to-bedside real-time optical monitoring system
Published in Journal of Biomedical Optics (01-06-2011)“…Background: The involvement of mitochondria in pathological states, such as neurodegenerative diseases, sepsis, stroke, and cancer, are well documented…”
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Microplate cell-retaining methodology for high-content analysis of individual non-adherent unanchored cells in a population
Published in Biomedical microdevices (01-12-2006)“…A high throughput Microtiter plate Cell Retainer (MCR) has been developed to enable, for the first time, high-content, time-dependent analysis of the same…”
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Tissue spectroscope: a novel in vivo approach to real time monitoring of tissue vitality
Published in Journal of biomedical optics (01-09-2004)“…Optical monitoring of various tissue physiological and biochemical parameters in real-time represents a significant new approach and a tool for better clinical…”
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Construction and use of an integrated electrochemical device for the detection of biologically relevant compounds released from non-adherent cells: Application for the electrochemical determination of nitric oxide produced by human U937 cells
Published in Electrochemistry communications (01-02-2006)“…This paper reports on a conceptually new experimental device dedicated to the electrochemical measurements of nitric oxide produced by non-adherent cells. This…”
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