Search Results - "Detwiler, J. T"

Broader Geographic Sampling Increases Extent of Intermediate Host Specificity for a Trematode Parasite (Notocotylidae: Quinqueserialis quinqueserialis) by Gagnon, D. K, Detwiler, J. T

“…Knowledge of helminth life cycles is essential to understanding their host specificity, geographic distribution, and transmission. Many helminth life cycle…”
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Cyclopropylamino Acid Amide as a Pharmacophoric Replacement for 2,3-Diaminopyridine. Application to the Design of Novel Bradykinin B sub(1) Receptor Antagonists by Wood, M R, Schirripa, K M, Kim, J J, Wan, B-L, Murphy, K L, Ransom, R W, Chang, RSL, Tang, C, Prueksaritanont, L T, Detwiler, T J, Hettrick, LA, Landis, E R, Leonard, Y M, Krueger, JA

“…Antagonism of the bradykinin B sub(1) receptor represents a potential treatment for chronic pain and inflammation. Novel antagonists were designed that display…”
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Metabolism-Directed Optimization of 3-Aminopyrazinone Acetamide Thrombin Inhibitors. Development of an Orally Bioavailable Series Containing P1 and P3 Pyridines by Burgey, Christopher S, Robinson, Kyle A, Lyle, Terry A, Sanderson, Philip E. J, Lewis, S. Dale, Lucas, Bobby J, Krueger, Julie A, Singh, Rominder, Miller-Stein, Cynthia, White, Rebecca B, Wong, Bradley, Lyle, Elizabeth A, Williams, Peter D, Coburn, Craig A, Dorsey, Bruce D, Barrow, James C, Stranieri, Maria T, Holahan, Marie A, Sitko, Gary R, Cook, Jacquelynn J, McMasters, Daniel R, McDonough, Colleen M, Sanders, William M, Wallace, Audrey A, Clayton, Franklin C, Bohn, Dennis, Leonard, Yvonne M, Detwiler, Theodore J, Lynch, Joseph J, Yan, Youwei, Chen, Zhongguo, Kuo, Lawrence, Gardell, Stephen J, Shafer, Jules A, Vacca, Joseph P

“…Recent efforts in the field of thrombin inhibitor research have focused on the identification of compounds with good oral bioavailability and pharmacokinetics…”
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Cyclopropylamino Acid Amide as a Pharmacophoric Replacement for 2,3-Diaminopyridine. Application to the Design of Novel Bradykinin B 1 Receptor Antagonists by Wood, Michael R., Schirripa, Kathy M., Kim, June J., Wan, Bang-Lin, Murphy, Kathy L., Ransom, Richard W., Chang, Raymond S. L., Tang, Cuyue, Prueksaritanont, Thomayant, Detwiler, Theodore J., Hettrick, Lisa A., Landis, Elizabeth R., Leonard, Yvonne M., Krueger, Julie A., Lewis, Sidney D., Pettibone, Douglas J., Freidinger, Roger M., Bock, Mark G.

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