Search Results - "Detweiler, Angela M"

Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses by Mick, Eran, Kamm, Jack, Pisco, Angela Oliveira, Ratnasiri, Kalani, Babik, Jennifer M., Castañeda, Gloria, DeRisi, Joseph L., Detweiler, Angela M., Hao, Samantha L., Kangelaris, Kirsten N., Kumar, G. Renuka, Li, Lucy M., Mann, Sabrina A., Neff, Norma, Prasad, Priya A., Serpa, Paula Hayakawa, Shah, Sachin J., Spottiswoode, Natasha, Tan, Michelle, Calfee, Carolyn S., Christenson, Stephanie A., Kistler, Amy, Langelier, Charles

“…SARS-CoV-2 infection is characterized by peak viral load in the upper airway prior to or at the time of symptom onset, an unusual feature that has enabled…”
Get full text

Integrated host/microbe metagenomics enables accurate lower respiratory tract infection diagnosis in critically ill children by Mick, Eran, Tsitsiklis, Alexandra, Kamm, Jack, Kalantar, Katrina L, Caldera, Saharai, Lyden, Amy, Tan, Michelle, Detweiler, Angela M, Neff, Norma, Osborne, Christina M, Williamson, Kayla M, Soesanto, Victoria, Leroue, Matthew, Maddux, Aline B, Simões, Eric Af, Carpenter, Todd C, Wagner, Brandie D, DeRisi, Joseph L, Ambroggio, Lilliam, Mourani, Peter M, Langelier, Charles R

“…BACKGROUNDLower respiratory tract infection (LRTI) is a leading cause of death in children worldwide. LRTI diagnosis is challenging because noninfectious…”
Get full text

Lettuce (Lactuca sativa) productivity influenced by microbial inocula under nitrogen-limited conditions in aquaponics by Day, Jessica A, Diener, Christian, Otwell, Anne E, Tams, Kourtney E, Bebout, Brad, Detweiler, Angela M, Lee, Michael D, Scott, Madeline T, Ta, Wilson, Ha, Monica, Carreon, Shienna A, Tong, Kenny, Ali, Abdirizak A, Gibbons, Sean M, Baliga, Nitin S

“…The demand for food will outpace productivity of conventional agriculture due to projected growth of the human population, concomitant with shrinkage of arable…”
Get full text

Upper airway gene expression shows a more robust adaptive immune response to SARS-CoV-2 in children by Mick, Eran, Tsitsiklis, Alexandra, Spottiswoode, Natasha, Caldera, Saharai, Serpa, Paula Hayakawa, Detweiler, Angela M., Neff, Norma, Pisco, Angela Oliveira, Li, Lucy M., Retallack, Hanna, Ratnasiri, Kalani, Williamson, Kayla M., Soesanto, Victoria, Simões, Eric A. F., Smith, Christiana, Abuogi, Lisa, Kistler, Amy, Wagner, Brandie D., DeRisi, Joseph L., Ambroggio, Lilliam, Mourani, Peter M., Langelier, Charles R.

“…Unlike other respiratory viruses, SARS-CoV-2 disproportionately causes severe disease in older adults whereas disease burden in children is lower. To…”
Get full text

Shotgun metagenome data of a defined mock community using Oxford Nanopore, PacBio and Illumina technologies by Sevim, Volkan, Lee, Juna, Egan, Robert, Clum, Alicia, Hundley, Hope, Lee, Janey, Everroad, R. Craig, Detweiler, Angela M., Bebout, Brad M., Pett-Ridge, Jennifer, Göker, Markus, Murray, Alison E., Lindemann, Stephen R., Klenk, Hans-Peter, O’Malley, Ronan, Zane, Matthew, Cheng, Jan-Fang, Copeland, Alex, Daum, Christopher, Singer, Esther, Woyke, Tanja

“…Metagenomic sequence data from defined mock communities is crucial for the assessment of sequencing platform performance and downstream analyses, including…”
Get full text

In host evolution of beta lactam resistance during active treatment for Pseudomonas aeruginosa bacteremia by Spottiswoode, Natasha, Hao, Samantha, Sanchez-Guerrero, Estella, Detweiler, Angela M, Mekonen, Honey, Neff, Norma, Macmillan, Henriette, Schwartz, Brian S, Engel, Joanne, DeRisi, Joseph L, Miller, Steven A, Langelier, Charles R

“…Multidrug-resistant (MDR) has been declared a serious threat by the United States Centers for Disease Control and Prevention. Here, we used whole genome…”
Get full text

Metagenomics reveals niche partitioning within the phototrophic zone of a microbial mat by Lee, Jackson Z, Everroad, R Craig, Karaoz, Ulas, Detweiler, Angela M, Pett-Ridge, Jennifer, Weber, Peter K, Prufert-Bebout, Leslie, Bebout, Brad M

“…Hypersaline photosynthetic microbial mats are stratified microbial communities known for their taxonomic and metabolic diversity and strong light-driven…”
Get full text

An Unusual Inverted Saline Microbial Mat Community in an Interdune Sabkha in the Rub' al Khali (the Empty Quarter), United Arab Emirates by McKay, Christopher P, Rask, Jon C, Detweiler, Angela M, Bebout, Brad M, Everroad, R Craig, Lee, Jackson Z, Chanton, Jeffrey P, Mayer, Marisa H, Caraballo, Adrian A L, Kapili, Bennett, Al-Awar, Meshgan, Al-Farraj, Asma

“…Salt flats (sabkha) are a recognized habitat for microbial life in desert environments and as analogs of habitats for possible life on Mars. Here we report on…”
Get full text

A 2-Gene Host Signature for Improved Accuracy of COVID-19 Diagnosis Agnostic to Viral Variants by Albright, Jack, Mick, Eran, Sanchez-Guerrero, Estella, Kamm, Jack, Mitchell, Anthea, Detweiler, Angela M, Neff, Norma, Tsitsiklis, Alexandra, Hayakawa Serpa, Paula, Ratnasiri, Kalani, Havlir, Diane, Kistler, Amy, DeRisi, Joseph L, Pisco, Angela Oliveira, Langelier, Charles R

“…The continued emergence of SARS-CoV-2 variants is one of several factors that may cause false-negative viral PCR test results. Such tests are also susceptible…”
Get full text

Assessing the role of alkaline soils on the carbon cycle at a playa site by Yates, Emma L, Detweiler, Angela M, Iraci, Laura T, Bebout, Brad M, McKay, Christopher P, Schiro, Kathleen, Sheffner, Edwin J, Kelley, Cheryl A, Tadić, Jovan M, Loewenstein, Max

“…Alkaline soils occupy approximately 5 % of the Earth’s land surface (7 million km), and this may increase due to the global trend towards increasing…”
Get full text

Discovery of Chlorophyll d: Isolation and Characterization of a Far-Red Cyanobacterium from the Original Site of Manning and Strain (1943) at Moss Beach, California by Kiang, Nancy Y, Swingley, Wesley D, Gautam, Dikshyant, Broddrick, Jared T, Repeta, Daniel J, Stolz, John F, Blankenship, Robert E, Wolf, Benjamin M, Detweiler, Angela M, Miller, Kathy Ann, Schladweiler, Jacob J, Lindeman, Ron, Parenteau, Mary N

“…We have isolated a chlorophyll-d-containing cyanobacterium from the intertidal field site at Moss Beach, on the coast of Central California, USA, where Manning…”
Get full text

Early prediction of preeclampsia in pregnancy with cell-free RNA by Moufarrej, Mira N., Vorperian, Sevahn K., Wong, Ronald J., Campos, Ana A., Quaintance, Cecele C., Sit, Rene V., Tan, Michelle, Detweiler, Angela M., Mekonen, Honey, Neff, Norma F., Baruch-Gravett, Courtney, Litch, James A., Druzin, Maurice L., Winn, Virginia D., Shaw, Gary M., Stevenson, David K., Quake, Stephen R.

“…Liquid biopsies that measure circulating cell-free RNA (cfRNA) offer an opportunity to study the development of pregnancy-related complications in a…”
Get full text

DiMeLo-seq: a long-read, single-molecule method for mapping protein–DNA interactions genome wide by Altemose, Nicolas, Maslan, Annie, Smith, Owen K., Sundararajan, Kousik, Brown, Rachel R., Mishra, Reet, Detweiler, Angela M., Neff, Norma, Miga, Karen H., Straight, Aaron F., Streets, Aaron

“…Studies of genome regulation routinely use high-throughput DNA sequencing approaches to determine where specific proteins interact with DNA, and they rely on…”
Get full text

Identification of a Polymorphism in the N Gene of SARS-CoV-2 That Adversely Impacts Detection by Reverse Transcription-PCR by Vanaerschot, Manu, Mann, Sabrina A, Webber, James T, Kamm, Jack, Bell, Sidney M, Bell, John, Hong, Si Noon, Nguyen, Minh Phuong, Chan, Lienna Y, Bhatt, Karan D, Tan, Michelle, Detweiler, Angela M, Espinosa, Alex, Wu, Wesley, Batson, Joshua, Dynerman, David, Wadford, Debra A, Puschnik, Andreas S, Neff, Norma, Ahyong, Vida, Miller, Steve, Ayscue, Patrick, Tato, Cristina M, Paul, Simon, Kistler, Amy L, DeRisi, Joseph L, Crawford, Emily D

Get full text

Discovering disease-causing pathogens in resource-scarce Southeast Asia using a global metagenomic pathogen monitoring system by Bohl, Jennifer A, Lay, Sreyngim, Chea, Sophana, Ahyong, Vida, Parker, Daniel M, Gallagher, Shannon, Fintzi, Jonathan, Man, Somnang, Ponce, Aiyana, Sreng, Sokunthea, Kong, Dara, Oliveira, Fabiano, Kalantar, Katrina, Tan, Michelle, Fahsbender, Liz, Sheu, Jonathan, Neff, Norma, Detweiler, Angela M, Yek, Christina, Ly, Sokna, Sath, Rathanak, Huch, Chea, Kry, Hok, Leang, Rithea, Huy, Rekol, Lon, Chanthap, Tato, Cristina M, DeRisi, Joseph L, Manning, Jessica E

“…SignificanceMetagenomic pathogen sequencing offers an unbiased approach to characterizing febrile illness. In resource-scarce settings with high biodiversity,…”
Get full text

Prolonged silent carriage, genomic virulence potential and transmission between staff and patients characterize a neonatal intensive care unit (NICU) outbreak of methicillin-resistant Staphylococcus aureus (MRSA) by Madera, Sharline, McNeil, Nicole, Serpa, Paula Hayakawa, Kamm, Jack, Pak, Christy, Caughell, Carolyn, Nichols, Amy, Dynerman, David, Li, Lucy M., Sanchez-Guerrero, Estella, Phelps, Maira S., Detweiler, Angela M., Neff, Norma, Reyes, Helen, Miller, Steve A., Yokoe, Deborah S., DeRisi, Joseph L., Ramirez-Avila, Lynn, Langelier, Charles R.

“…Methicillin-resistant (MRSA) is an important pathogen in neonatal intensive care units (NICU) that confers significant morbidity and mortality. Improving our…”
Get full text

Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes by Winkler, Juliane, Tan, Weilun, Diadhiou, Catherine Mm, McGinnis, Christopher S, Abbasi, Aamna, Hasnain, Saad, Durney, Sophia, Atamaniuc, Elena, Superville, Daphne, Awni, Leena, Lee, Joyce V, Hinrichs, Johanna H, Wagner, Patrick S, Singh, Namrata, Hein, Marco Y, Borja, Michael, Detweiler, Angela M, Liu, Su-Yang, Nanjaraj, Ankitha, Sitarama, Vaishnavi, Rugo, Hope S, Neff, Norma, Gartner, Zev J, Oliveira Pisco, Angela, Goga, Andrei, Darmanis, Spyros, Werb, Zena

“…Metastasis is the leading cause of cancer-related deaths. It is unclear how intratumor heterogeneity (ITH) contributes to metastasis and how metastatic cells…”
Get full text

Enabling Data Discovery with the Astrobiology Resource Metadata Standard by Wolfe, Shawn R, Lafuente, Barbara, Keller, Richard M, Detweiler, Angela M, Bristow, Thomas F, Parenteau, Mary N, Boydstun, Kevin, Dateo, Christopher E, Des Marais, David J, Jahnke, Linda L, Rojo, Sara, Stone, Nathan, Vorobets, Mark

“…As scientific investigations increasingly adopt Open Science practices, reuse of data becomes paramount. However, despite decades of progress in internet…”
Get more information

High importance of autochthonous basal food source for the food web of a Brazilian tropical stream regardless of shading by Neres-Lima, Vinicius, Brito, Ernesto F., Krsulović, Felipe A. M., Detweiler, Angela M., Hershey, Anne E., Moulton, Timothy P.

“…According to the prevalent paradigm, the major source of carbon and energy for food webs of small forested streams in temperate regions is allochthonous…”
Get full text

METAGENOMICS FOR PATHOGEN DETECTION DURING A MASS MORTALITY EVENT IN SONGBIRDS by Mwakibete, Lusajo, Greening, Sabrina S., Kalantar, Katrina, Ahyong, Vida, Anis, Eman, Miller, Erica A., Needle, David B., Oglesbee, Michael, Thomas, W. Kelley, Sevigny, Joseph L., Gordon, Lawrence M., Nemeth, Nicole M., Ogbunugafor, C. Brandon, Ayala, Andrea J., Faith, Seth A., Neff, Norma, Detweiler, Angela M., Baillargeon, Tessa, Tanguay, Stacy, Simpson, Stephen D., Murphy, Lisa A., Ellis, Julie C., Tato, Cristina M., Gagne, Roderick B.

“…Mass mortality events in wildlife can be indications of an emerging infectious disease. During the spring and summer of 2021, hundreds of dead passerines were…”
Get full text