Search Results - "Dettmar, P."

Thickness and continuity of the adherent colonic mucus barrier in active and quiescent ulcerative colitis and Crohn's disease by Strugala, V, Dettmar, P W, Pearson, J P

“…The colon is covered by a mucus barrier that protects the underlying mucosa and alterations in this mucus barrier have been implicated in the aetiology of…”
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Topical protection of human esophageal mucosal integrity by Woodland, P, Batista-Lima, F, Lee, C, Preston, S L, Dettmar, P, Sifrim, D

“…Patients with nonerosive reflux disease exhibit impaired esophageal mucosal integrity, which may underlie enhanced reflux perception. In vitro topical…”
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Alginate as a Source of Dietary Fiber by Brownlee, I. A., Allen, A., Pearson, J. P., Dettmar, P. W., Havler, M. E., Atherton, M. R., Onsøyen, E.

“…Alginate, an algal polysaccharide, is widely used in the food industry as a stabilizer, or as a thickening or emulsifying agent. As an indigestible…”
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Daily ingestion of alginate reduces energy intake in free-living subjects by Paxman, J.R., Richardson, J.C., Dettmar, P.W., Corfe, B.M.

“…Sodium alginate is a seaweed-derived fibre that has previously been shown to moderate appetite in models of acute feeding. The mechanisms underlying this…”
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Post‐prandial reflux suppression by a raft‐forming alginate (Gaviscon Advance) compared to a simple antacid documented by magnetic resonance imaging and pH‐impedance monitoring: mechanistic assessment in healthy volunteers and randomised, controlled, double‐blind study in reflux patients by Sweis, R., Kaufman, E., Anggiansah, A., Wong, T., Dettmar, P., Fried, M., Schwizer, W., Avvari, R. K., Pal, A., Fox, M.

“…Summary Background Alginates form a raft above the gastric contents, which may suppress gastro‐oesophageal reflux; however, inconsistent effects have been…”
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Alginate rafts and their characterisation by Hampson, F.C., Farndale, A., Strugala, V., Sykes, J., Jolliffe, I.G., Dettmar, P.W.

“…Alginate/antacid anti-reflux preparations are designed to provide symptom relief by forming a physical barrier on top of the stomach contents in the form of a…”
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The online Cough Clinic: developing guideline-based diagnosis and advice by Dettmar, P. W, Strugala, V, Fathi, H, Dettmar, H. J, Wright, C, Morice, A. H

“…The aim of the present study was make chronic cough guidelines more practical and user friendly by developing an internet-based interactive diagnostic…”
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Characterisation of adherens and tight junctional molecules in normal animal larynx; determining a suitable model for studying molecular abnormalities in human laryngopharyngeal reflux by Gill, G A, Buda, A, Moorghen, M, Dettmar, P W, Pignatelli, M

“…Background: The disruption of intercellular junctions in the larynx is a pathological feature of laryngopharyngeal reflux (LPR). Good experimental models are…”
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Rapid onset of effect of sodium alginate on gastro-oesophageal reflux compared with ranitidine and omeprazole, and relationship between symptoms and reflux episodes by Dettmar, P W, Sykes, J, Little, S L, Bryan, J

“…The objective of the open, randomised, four-period crossover study was to compare the time of onset of effect of sodium alginate (SA), omeprazole, ranitidine…”
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An in vitro mucosal model for prediction of the bioadhesion of alginate solutions to the oesophagus by Batchelor, H.K, Banning, D, Dettmar, P.W, Hampson, F.C, Jolliffe, I.G, Craig, D.Q.M

“…This paper discusses the development of an in vitro model utilised to assess the adhesion of alginate solutions to porcine oesophageal tissue. The methodology…”
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Limited value of endorectal magnetic resonance imaging and transrectal ultrasonography in the staging of clinically localized prostate cancer by May, F., Treumann, T., Dettmar, P., Hartung, R., Breul, J.

“…Objective To examine the role of endorectal magnetic resonance imaging (eMRI) and transrectal ultrasonography (TRUS) for clinically localized prostate cancer…”
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Habitual micronutrient intake during and after pregnancy in Caucasian Londoners by Derbyshire, E., Davies, G.J., Costarelli, V., Dettmar, P.W.

“…Micronutrient status is of fundamental importance both upon conception and throughout pregnancy. There is an abundance of literature investigating nutrient…”
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Overweight and obesity challenges in the Cystic Fibrosis population – a need for revision in nutritional advice? by Crossfield, G. L., Krishnan, A., Bourke, S., Anderson, A., Gurney, A., Dettmar, P. W., Brownlee, I., Ward, C., Pearson, J. P.

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Bowel habit, diet and body weight in preadolescent children by Jennings, A, Davies, G.J, Costarelli, V, Dettmar, P.W

“…The possible influence of diet and body weight on bowel habit in children is unknown. The present study aimed to investigate the inter-relationships between…”
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Comparison of two in vivo and two ex vivo tests to assess the antibacterial activity of several antiseptics by Messager, S., Goddard, P.A., Dettmar, P.W., Maillard, J.-Y.

“…An ex vivo test was adapted to mimic the in vivo conditions of testing antiseptic activity on human forearms and in the European Standard Hygienic Handwash…”
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Diet and lifestyle triggers for gastro-oesophageal reflux disease: symptom identification by Oliver, K. L., Davies, G. J., Dettmar, P. W.

“…In light of these interesting findings further investigation is needed to gain a better understanding of these diet and lifestyle trigger factors and their…”
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Heartburn: impact on physical activity level by Oliver, K. L., Davies, G. J., Dettmar, P. W.

“…All participants completed a lifestyle questionnaire including self-reported height and weight and the international physical activity questionnaire (IPAQ)(2)…”
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Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc by KUHN, W, SCHMALFELDT, B, JÄNICKE, F, SCHMITT, M, GRAEFF, H, REUNING, U, PACHE, L, BERGER, U, ULM, K, HARBECK, N, SPÄTHE, K, DETTMAR, P, HÖFLER, H

“…Strong evidence has accumulated on the prognostic value of tumour-associated proteolytic factors in patients afflicted with solid malignant tumours, including…”
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The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro by Howling, Graeme I, Dettmar, Peter W, Goddard, Paul A, Hampson, Frank C, Dornish, Michael, Wood, Edward J

“…The effects of chitin [(1→4)-2-acetamido-2-deoxy- β- d-glucan] and its partially deacetylated derivatives, chitosans, on the proliferation of human dermal…”
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Prepregnancy body mass index and dietary intake in the first trimester of pregnancy by Derbyshire, E, Davies, J, Costarelli, V, Dettmar, P

“…Adequate maternal nutrition is of paramount importance in pregnancy, particularly in the first trimester when fetal development is crucial. It has been…”
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