Search Results - "Detterich, Jon"
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1
Exercise Performance: A Fontan Phenotype Predictive of Long-Term Survival
Published in JACC. Advances (Online) (01-10-2024)“…[Display omitted]…”
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2
Myocardial fibrosis: the heart of diastole?
Published in Blood (13-07-2017)Get full text
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Nitric oxide, vasodilation and the red blood cell
Published in Biorheology (Oxford) (01-01-2014)“…Since the identification of the elusive endothelium-derived relaxing factor as nitric oxide (NO), much attention has been devoted to understanding its…”
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4
Blood Rheology and Hemodynamics: Still Illuminating after 20 Years
Published in Seminars in thrombosis and hemostasis (01-09-2024)Get more information
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Simple chronic transfusion therapy, a crucial therapeutic option for sickle cell disease, improves but does not normalize blood rheology: What should be our goals for transfusion therapy?
Published in Clinical hemorheology and microcirculation (01-01-2018)“…Sickle cell anemia is characterized by a mutation resulting in the formation of an abnormal beta-hemoglobin called hemoglobin S. Hemoglobin S polymerizes upon…”
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Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease
Published in PloS one (24-05-2017)“…Painful vaso-occlusive crisis (VOC), a complication of sickle cell disease (SCD), occurs when sickled red blood cells obstruct flow in the microvasculature. We…”
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Red blood cell mechanical sensitivity improves in patients with sickle cell disease undergoing chronic transfusion after prolonged, subhemolytic shear exposure
Published in Transfusion (Philadelphia, Pa.) (01-12-2018)“…Background Sickle cell disease (SCD) is a genetically inherited hemoglobinopathy in which deoxygenated hemoglobin S polymerizes, leading to stiff red blood…”
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Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease
Published in Blood (06-08-2015)“…Tricuspid regurgitant (TR) jet velocity and its relationship to pulmonary hypertension has been controversial in sickle cell disease (SCD). Plasma free…”
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Procedural, pregnancy, and short‐term outcomes after fetal aortic valvuloplasty
Published in Catheterization and cardiovascular interventions (01-09-2020)“…Objectives We aimed to evaluate the effect of technical aspects of fetal aortic valvuloplasty (FAV) on procedural risks and pregnancy outcomes. Background FAV…”
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10
Kidney iron deposition by R2 is associated with haemolysis and urinary iron
Published in British journal of haematology (01-05-2021)“…Summary Kidney iron deposition measured by R2* (magnetic resonance imaging) MRI is posited to result from tubular reabsorption of filtered haemoglobin due to…”
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Decreased erythrocyte aggregation in Glenn and Fontan: univentricular circulation as a rheologic disease model
Published in Pediatric research (01-04-2024)“…Background In the Fontan palliation for single ventricle heart disease (SVHD), pulmonary blood flow is non-pulsatile/passive, low velocity, and low shear,…”
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12
Physical Properties of Blood and their Relationship to Clinical Conditions
Published in Frontiers in physiology (06-07-2022)“…It has been long known that blood health heavily influences optimal physiological function. Abnormalities affecting the physical properties of blood have been…”
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13
Mental stress causes vasoconstriction in subjects with sickle cell disease and in normal controls
Published in Haematologica (Roma) (01-01-2020)“…Vaso-occlusive crisis (VOC) is a hallmark of sickle cell disease (SCD) and occurs when deoxygenated sickled red blood cells occlude the microvasculature. Any…”
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Multiresolution Comparison of Fetal CINE MRI at 0.55T
Published in Journal of cardiovascular magnetic resonance (2024)Get full text
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Longitudinal Follow-Up of Children With HLHS and Association Between Norwood Shunt Type and Long-Term Outcomes: The SVR III Study
Published in Circulation (New York, N.Y.) (24-10-2023)“…In the SVR trial (Single Ventricle Reconstruction), newborns with hypoplastic left heart syndrome were randomly assigned to receive a modified…”
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Mediastinal infantile hemangioma with spinal canal extension and extensive gastrointestinal involvement complicated by respiratory failure
Published in Pediatric blood & cancer (01-11-2022)“…Infantile hemangioma is the most common soft tissue tumor of infancy. Extensive organ involvement is rare. This report describes an infant with biopsy…”
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Individual red blood cell nitric oxide production in sickle cell anemia: Nitric oxide production is increased and sickle shaped cells have unique morphologic change compared to discoid cells
Published in Free radical biology & medicine (01-08-2021)“…Sickle cell anemia (SCA) is characterized by decreased red blood cell (RBC) deformability due to polymerization of deoxygenated hemoglobin, leading to abnormal…”
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Accuracy of a Novel Handheld Wireless Platform for Detection of Cardiac Dysfunction in Anthracycline-Exposed Survivors of Childhood Cancer
Published in Clinical cancer research (01-07-2018)“…Childhood cancer survivors are at risk for anthracycline-related cardiac dysfunction, often developing at a time when they are least engaged in long-term…”
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Loss of alpha‐globin genes in human subjects is associated with improved nitric oxide‐mediated vascular perfusion
Published in American journal of hematology (01-03-2021)“…Alpha thalassemia is a hemoglobinopathy due to decreased production of the α‐globin protein from loss of up to four α‐globin genes, with one or two missing in…”
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