Search Results - "Detterich, Jon"

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    Nitric oxide, vasodilation and the red blood cell by Simmonds, Michael J, Detterich, Jon A, Connes, Philippe

    Published in Biorheology (Oxford) (01-01-2014)
    “…Since the identification of the elusive endothelium-derived relaxing factor as nitric oxide (NO), much attention has been devoted to understanding its…”
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    Journal Article
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    Simple chronic transfusion therapy, a crucial therapeutic option for sickle cell disease, improves but does not normalize blood rheology: What should be our goals for transfusion therapy? by Detterich, Jon A

    Published in Clinical hemorheology and microcirculation (01-01-2018)
    “…Sickle cell anemia is characterized by a mutation resulting in the formation of an abnormal beta-hemoglobin called hemoglobin S. Hemoglobin S polymerizes upon…”
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    Journal Article
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    Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease by Chalacheva, Patjanaporn, Khaleel, Maha, Sunwoo, John, Shah, Payal, Detterich, Jon A, Kato, Roberta M, Thuptimdang, Wanwara, Meiselman, Herbert J, Sposto, Richard, Tsao, Jennie, Wood, John C, Zeltzer, Lonnie, Coates, Thomas D, Khoo, Michael C K

    Published in PloS one (24-05-2017)
    “…Painful vaso-occlusive crisis (VOC), a complication of sickle cell disease (SCD), occurs when sickled red blood cells obstruct flow in the microvasculature. We…”
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    Red blood cell mechanical sensitivity improves in patients with sickle cell disease undergoing chronic transfusion after prolonged, subhemolytic shear exposure by Simmonds, Michael J., Suriany, Silvie, Ponce, Derek, Detterich, Jon A.

    Published in Transfusion (Philadelphia, Pa.) (01-12-2018)
    “…Background Sickle cell disease (SCD) is a genetically inherited hemoglobinopathy in which deoxygenated hemoglobin S polymerizes, leading to stiff red blood…”
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    Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease by Detterich, Jon A., Kato, Roberta M., Rabai, Miklos, Meiselman, Herbert J., Coates, Thomas D., Wood, John C.

    Published in Blood (06-08-2015)
    “…Tricuspid regurgitant (TR) jet velocity and its relationship to pulmonary hypertension has been controversial in sickle cell disease (SCD). Plasma free…”
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    Kidney iron deposition by R2 is associated with haemolysis and urinary iron by Denton, Christopher C., Detterich, Jon A., Coates, Thomas D., Wood, John C.

    Published in British journal of haematology (01-05-2021)
    “…Summary Kidney iron deposition measured by R2* (magnetic resonance imaging) MRI is posited to result from tubular reabsorption of filtered haemoglobin due to…”
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    Decreased erythrocyte aggregation in Glenn and Fontan: univentricular circulation as a rheologic disease model by Suriany, Silvie, Liu, Honglei, Cheng, Andrew L., Wenby, Rosalinda, Patel, Neil, Badran, Sarah, Meiselman, Herbert J., Denton, Christopher, Coates, Thomas D., Wood, John C., Detterich, Jon A.

    Published in Pediatric research (01-04-2024)
    “…Background In the Fontan palliation for single ventricle heart disease (SVHD), pulmonary blood flow is non-pulsatile/passive, low velocity, and low shear,…”
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    Physical Properties of Blood and their Relationship to Clinical Conditions by Alexy, Tamas, Detterich, Jon, Connes, Philippe, Toth, Kalman, Nader, Elie, Kenyeres, Peter, Arriola-Montenegro, Jose, Ulker, Pinar, Simmonds, Michael J.

    Published in Frontiers in physiology (06-07-2022)
    “…It has been long known that blood health heavily influences optimal physiological function. Abnormalities affecting the physical properties of blood have been…”
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    Mental stress causes vasoconstriction in subjects with sickle cell disease and in normal controls by Shah, Payal, Khaleel, Maha, Thuptimdang, Wanwara, Sunwoo, John, Veluswamy, Saranya, Chalacheva, Patjanaporn, Kato, Roberta M, Detterich, Jon, Wood, John C, Zeltzer, Lonnie, Sposto, Richard, Khoo, Michael C K, Coates, Thomas D

    Published in Haematologica (Roma) (01-01-2020)
    “…Vaso-occlusive crisis (VOC) is a hallmark of sickle cell disease (SCD) and occurs when deoxygenated sickled red blood cells occlude the microvasculature. Any…”
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    Mediastinal infantile hemangioma with spinal canal extension and extensive gastrointestinal involvement complicated by respiratory failure by Cohen‐Cutler, Sally, Detterich, Jon A., Miller, Joseph M., Anselmo, Dean M., Luu, Minnelly, Mascarenhas, Leo

    Published in Pediatric blood & cancer (01-11-2022)
    “…Infantile hemangioma is the most common soft tissue tumor of infancy. Extensive organ involvement is rare. This report describes an infant with biopsy…”
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