Search Results - "Detorio, Mervi"

A Comprehensive Approach to Assuring Quality of Laboratory Testing in HIV Surveys: Lessons Learned From the Population-Based HIV Impact Assessment Project by Patel, Hetal K., Duong, Yen T., Birhanu, Sehin, Dobbs, Trudy, Lupoli, Kathryn, Moore, Carole, Detorio, Mervi, Sleeman, Katrina, Manjengwa, Julius, Wray-Gordon, Floris, Yavo, Daniel, Jackson, Keisha, Domaoal, Robert A., Yufenyuy, Ernest L., Vedapuri, Shanmugam, Ndongmo, Clement B., Ogollah, Francis M., Dzinamarira, Tafadzwa, Rubinstein, Paul, Sachathep, Karampreet K., Metz, Melissa, Longwe, Herbert, Saito, Suzue, Brown, Kristin, Voetsch, Andrew C., Parekh, Bharat S.

“…Conducting HIV surveys in resource-limited settings is challenging because of logistics, limited availability of trained personnel, and complexity of testing…”
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Cellular Pharmacology and Potency of HIV-1 Nucleoside Analogs in Primary Human Macrophages by GAVEGNANO, Christina, DETORIO, Mervi A, BASSIT, Leda, HURWITZ, Selwyn J, NORTH, Thomas W, SCHINAZI, Raymond F

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Randomized Clinical Trial of HIV Treatment Adherence Counseling Interventions for People Living With HIV and Limited Health Literacy by Kalichman, Seth C, Cherry, Chauncey, Kalichman, Moira O, Amaral, Christina, White, Denise, Grebler, Tamar, Eaton, Lisa A, Cruess, Dean, Detorio, Mervi A, Caliendo, Angela M, Schinazi, Raymond F

“…BACKGROUND:Limited health literacy is a known barrier to medication adherence among people living with HIV. Adherence improvement interventions are urgently…”
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Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′,3′-dideoxy-2′,2′-difluoro-4′-azanucleosides by Martínez-Montero, Saúl, Fernández, Susana, Sanghvi, Yogesh S., Theodorakis, Emmanuel A., Detorio, Mervi A., Mcbrayer, Tamara R., Whitaker, Tony, Schinazi, Raymond F., Gotor, Vicente, Ferrero, Miguel

“…A series of 2′,3′-dideoxy-2′,2′-difluoro-4′-azanucleosides of both pyrimidine and purine nucleobases were synthesized in an efficient manner starting from…”
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A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors by BRENNER, Bluma, TURNER, Dan, OLIVEIRA, Maureen, MOISI, Daniela, DETORIO, Mervi, CAROBENE, Mauricio, MARLINK, Richard G, SCHAPIRO, Jonathan, ROGER, Michel, WAINBERG, Mark A

“…We have shown that HIV-1 clade C variants contain a valine codon 106 polymorphism (GTG) that facilitates a V106M transition (GTG<--ATG) after selection with…”
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Use of dietary supplements among people living with HIV/AIDS is associated with vulnerability to medical misinformation on the internet by Kalichman, Seth C, Cherry, Chauncey, White, Denise, Jones, Miche'l, Kalichman, Moira O, Detorio, Mervi A, Caliendo, Angela M, Schinazi, Raymond F

“…Use of dietary supplements is common among people living with HIV/AIDS. Because dietary supplements are used in the context of other health behaviors, they may…”
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Synthesis and antiviral evaluation of 2-amino-6-carbamoylpurine dioxolane nucleoside derivatives and their phosphoramidates prodrugs by Cho, Jong Hyun, Bondana, Lavanya, Detorio, Mervi A., Montero, Cathy, Bassit, Leda C., Amblard, Franck, Coats, Steven J., Schinazi, Raymond F.

“…[Display omitted] The synthesis of 9-(β-d-1,3-dioxolan-4-yl)2,6-diaminopurine nucleoside phosphoramidate prodrugs as well as various 2-amino-6-carbamoylpurine…”
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Performance evaluation of the Asante Rapid Recency Assay for verification of HIV diagnosis and detection of recent HIV-1 infections: Implications for epidemic control by Yufenyuy, Ernest L, Detorio, Mervi, Dobbs, Trudy, Patel, Hetal K, Jackson, Keisha, Vedapuri, Shanmugam, Parekh, Bharat S

“…We previously described development of a rapid test for recent infection (RTRI) that can diagnose HIV infection and detect HIV-1 recent infections in a single…”
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Synthesis and evaluation of Janus type nucleosides as potential HCV NS5B polymerase inhibitors by Zhou, Longhu, Amblard, Franck, Zhang, Hongwang, McBrayer, Tamara R., Detorio, Mervi A., Whitaker, Tony, Coats, Steven J., Schinazi, Raymond F.

“…The synthesis of new ribo and 2′-β-C-methyl ribo Janus type nucleosides J-AA, J-AG and J-AU is reported along with their ability to block HCV and HIV…”
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Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′- C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5′-triphosphates by Shi, Junxing, Zhou, Longhu, Zhang, Hongwang, McBrayer, Tamara R., Detorio, Mervi A., Johns, Melissa, Bassit, Leda, Powdrill, Megan H., Whitaker, Tony, Coats, Steven J., Götte, Matthias, Schinazi, Raymond F.

“…Thirty novel α- and β- d-2′-deoxy-2′-fluoro-2′- C-methyl-7-deazapurine nucleoside analogs were synthesized and evaluated for in vitro antiviral activity…”
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Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol by Amblard, Franck, Govindarajan, Baskaran, Lefkove, Benjamin, Rapp, Kimberly L., Detorio, Mervi, Arbiser, Jack L., Schinazi, Raymond F.

“…The synthesis of a series of new bisphenol derivatives bearing allylic moieties as potential analogs of honokiol and/or magnolol is reported. Certain compounds…”
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Persistence and Fitness of Multidrug-Resistant Human Immunodeficiency Virus Type 1 Acquired in Primary Infection by Brenner, Bluma G, Routy, Jean-Pierre, Petrella, Marco, Moisi, Daniela, Oliveira, Maureen, Detorio, Mervi, Spira, Bonnie, Essabag, Vidal, Conway, Brian, Lalonde, Richard, Sekaly, Rafick-Pierre, Wainberg, Mark A

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Performance of HIV rapid testing algorithm in Nigeria: Findings from a household-based Nigeria HIV/AIDS Indicator and Impact Survey (NAIIS) by Patel, Hetal K, Ikpe, Sunday, Bronson, Megan, Birhanu, Sehin, Abimiku, Alash'le, Jahun, Ibrahim, Detorio, Mervi, Lupoli, Kathryn, Yavo, Daniel, Bassey, Orji O, Jelpe, Tapdiyel D, Kagurusi, Brian, Iriemenam, Nnaemeka C, Patel, Divya, Okoye, McPaul I, Dalhatu, Ibrahim T, Ohakanu, Stephen, Voetsch, Andrew C, Aliyu, Sani, Ashefor, Gregory, Gambo, Aliyu, Ikwulono, Gabriel O, Nzelu, Charles, Adewole, Isaac F, Swaminathan, Mahesh, Parekh, Bharat

“…The Nigeria AIDS Indicator and Impact Survey (NAIIS), a cross-sectional household survey, was conducted in 2018 with primary objectives to estimate HIV…”
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Retinazone Inhibits Certain Blood-Borne Human Viruses Including Ebola Virus Zaire by Kesel, Andreas J, Huang, Zhuhui, Murray, Michael G, Prichard, Mark N, Caboni, Laura, Nevin, Daniel K, Fayne, Darren, Lloyd, David G, Detorio, Mervi A, Schinazi, Raymond F

“…Background: Human HBV and HIV integrate their retro-transcribed DNA proviruses into the human host genome. Existing antiretroviral drug regimens fail to…”
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Selection and Characterization of HIV-1 with a Novel S68 Deletion in Reverse Transcriptase by SCHINAZI, Raymond F, MASSUD, Ivana, RAPP, Kimberly L, CRISTIANO, Meta, DETORIO, Mervi A, STANTON, Richard A, BENNETT, Matthew A, KIERLIN-DUNCAN, Monique, LENNERSTRAND, Johan, NETTLES, James H

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Pre-steady-state Kinetic Studies Establish Entecavir 5′-Triphosphate as a Substrate for HIV-1 Reverse Transcriptase by Domaoal, Robert A., McMahon, Moira, Thio, Chloe L., Bailey, Christopher M., Tirado-Rives, Julian, Obikhod, Aleksander, Detorio, Mervi, Rapp, Kimberly L., Siliciano, Robert F., Schinazi, Raymond F., Anderson, Karen S.

“…The novel 2′-deoxyguanosine analog Entecavir (ETV) is a potent inhibitor of hepatitis B virus (HBV) replication and is recommended for treatment in human…”
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Genetic Divergence of Human Immunodeficiency Virus Type 1 Ethiopian Clade C Reverse Transcriptase (RT) and Rapid Development of Resistance against Nonnucleoside Inhibitors of RT by Loemba, Hugues, Brenner, Bluma, Parniak, Michael A, Ma'ayan, Shlomo, Spira, Bonnie, Moisi, Daniela, Oliveira, Maureen, Detorio, Mervi, Wainberg, Mark A

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Antiviral Agents Derived from Novel 1-adamantyl Singlet Nitrenes by Kesel, Andreas J, Weiss, Hans-Christoph, Schönleber, Andreas, Day, Craig W, Barnard, Dale L, Detorio, Mervi A, Schinazi, Raymond F

“…Background: Amantadine constitutes an interesting, diamond crystal lattice-shaped, antivirally active amine with an inhibitory effect on influenza A viruses…”
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Long-Term Exposure to AZT, but not d4T, Increases Endothelial Cell Oxidative Stress and Mitochondrial Dysfunction by Kline, Erik R., Bassit, Leda, Hernandez-Santiago, Brenda I., Detorio, Mervi A., Liang, Bill, Kleinhenz, Dean J., Walp, Erik R., Dikalov, Sergey, Jones, Dean P., Schinazi, Raymond F., Sutliff, Roy L.

“…Nucleoside reverse transcriptase inhibitors (NRTIs), such as zidovudine (AZT) and stavudine (d4T), cause toxicities to numerous tissues, including the liver…”
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Anti-Human Immunodeficiency Virus Activity, Cross-Resistance, Cytotoxicity, and Intracellular Pharmacology of the 3′-Azido-2′,3′-Dideoxypurine Nucleosides by SLUIS-CREMER, Nicolas, KOONTZ, Dianna, SCHINAZI, Raymond F, MELLORS, John W, BASSIT, Leda, HERNANDEZ-SANTIAGO, Brenda I, DETORIO, Mervi, RAPP, Kim L, AMBLARD, Franck, BONDADA, Lavanya, GRIER, Jason, COATS, Steven J

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