Search Results - "Detloff, P.J."

Analysis of the 5′ end of the mouse Elavl1 ( mHuA) gene reveals a transcriptional regulatory element and evidence for conserved genomic organization by King, P.H., Fuller, J.J., Nabors, L.B., Detloff, P.J.

“…mHuA ( Elavl1) belongs to a highly conserved family of genes encoding RNA-binding proteins and has been linked to cell growth and proliferation through its…”
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A Role for PGC-1α in Transcription and Excitability of Neocortical and Hippocampal Excitatory Neurons by McMeekin, L.J., Bartley, A.F., Bohannon, A.S., Adlaf, E.W., van Groen, T., Boas, S.M., Fox, S.N., Detloff, P.J., Crossman, D.K., Overstreet-Wadiche, L.S., Hablitz, J.J., Dobrunz, L.E., Cowell, R.M.

“…•Loss of PGC-1α in PNs enhances glutamatergic transmission in the neocortex and hippocampus.•Deletion of PGC-1α from pyramidal neurons (PNs) caused ambulatory…”
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Purkinje cell dysfunction and loss in a knock-in mouse model of Huntington Disease by Dougherty, S.E., Reeves, J.L., Lesort, M., Detloff, P.J., Cowell, R.M.

“…Huntington Disease (HD) is an autosomal dominant neurological disorder characterized by motor, psychiatric and cognitive disturbances. Recent evidence…”
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Neuronal intranuclear inclusions and neuropil aggregates in Hdh CAG(150) knockin mice by Tallaksen-Greene, S.J., Crouse, A.B., Hunter, J.M., Detloff, P.J., Albin, R.L.

“…We studied the development of neuronal intranuclear inclusions (NIIs), neuropil aggregates (NAs), and expression of expanded repeat polyglutamine protein in…”
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Neuronal intranuclear inclusions and neuropil aggregates in HdhCAG(150) knockin mice by TALLAKSEN-GREENE, S. J, CROUSE, A. B, HUNTER, J. M, DETLOFF, P. J, ALBIN, R. L

“…We studied the development of neuronal intranuclear inclusions (NIIs), neuropil aggregates (NAs), and expression of expanded repeat polyglutamine protein in…”
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