Search Results - "Detloff, Megan R."

Peroxynitrite-mediated protein nitration and lipid peroxidation in a mouse model of traumatic brain injury by Hall, Edward D, Detloff, Megan R, Johnson, Kjell, Kupina, Nancy C

“…The role of reactive oxygen-induced oxidative damage to lipids (i.e., lipid peroxidation, LP) and proteins has been strongly supported in previous work. Most…”
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Modelling at‐level allodynia after mid‐thoracic contusion in the rat by Blumenthal, Gary H., Nandakumar, Bharadwaj, Schnider, Ashley K., Detloff, Megan R., Ricard, Jerome, Bethea, John R., Moxon, Karen A.

“…Background The rat mid‐thoracic contusion model has been used to study at‐level tactile allodynia, a common type of pain that develops after spinal cord injury…”
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Enhanced nociceptive behavior and expansion of associated primary afferents in a rabbit model of cerebral palsy by Reedich, Emily J., Genry, Landon T., Singer, Meredith A., Cavarsan, Clarissa Fantin, Mena Avila, Elvia, Boudreau, Daphne M., Brennan, Michael C., Garrett, Alyssa M., Dowaliby, Lisa, Detloff, Megan R., Quinlan, Katharina A.

“…Spastic cerebral palsy (CP) is a movement disorder marked by hypertonia and hyperreflexia; the most prevalent comorbidity is pain. Since spinal nociceptive…”
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Histological identification of phrenic afferent projections to the spinal cord by Nair, Jayakrishnan, Bezdudnaya, Tatiana, Zholudeva, Lyandysha, Detloff, Megan R, Reier, Paul J, Lane, Michael A, Fuller, David D

“…Highlights • In adult rats the phrenic nerve was soaked in cholera toxin beta (CT-β) or Cascade Blue. • CT-β was also delivered intrapleurally or via direct…”
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Expressing Constitutively Active Rheb in Adult Dorsal Root Ganglion Neurons Enhances the Integration of Sensory Axons that Regenerate Across a Chondroitinase-Treated Dorsal Root Entry Zone Following Dorsal Root Crush by Wu, Di, Klaw, Michelle C, Kholodilov, Nikolai, Burke, Robert E, Detloff, Megan R, Côté, Marie-Pascale, Tom, Veronica J

“…While the peripheral branch of dorsal root ganglion neurons (DRG) can successfully regenerate after injury, lesioned central branch axons fail to regrow across…”
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Stepwise motor and all-or-none sensory recovery is associated with nonlinear sparing after incremental spinal cord injury in rats by Kloos, Anne D., Fisher, Lesley C., Detloff, Megan R., Hassenzahl, David L., Basso, D. Michele

“…Spinal cord injury (SCI) causes motor and sensory deficits that impair functional performance. While more functional recovery occurs with greater white matter…”
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Plasticity in ascending long propriospinal and descending supraspinal pathways in chronic cervical spinal cord injured rats by Côté, Marie-Pascale, Detloff, Megan R, Wade, Jr, Rodel E, Lemay, Michel A, Houlé, John D

“…The high clinical relevance of models of incomplete cervical spinal cord injury (SCI) creates a need to address the spontaneous neuroplasticity that underlies…”
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Cytoskeletal protein degradation and neurodegeneration evolves differently in males and females following experimental head injury by Kupina, Nancy C, Detloff, Megan R, Bobrowski, Walter F, Snyder, Bradley J, Hall, Edward D

“…The resulting neuropathological degeneration that occurs following a traumatic brain injury (TBI) is a consequence of both immediate and secondary…”
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Neuroimmunophilin ligand V-10,367 is neuroprotective after 24-hour delayed administration in a mouse model of diffuse traumatic brain injury by KUPINA, Nancy C, DETLOFF, Megan R, DUTTA, Satavisha, HALL, Edward D

“…The authors present two studies that investigate the biochemical and histologic effects of the nonimmunosuppressive neuroimmunophilin (NIMM) ligand V-10,367 in…”
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Neuroimmunophilin Ligand V-10,367 Is Neuroprotective After 24-Hour Delayed Administration in a Mouse Model of Diffuse Traumatic Brain Injury by Kupina, Nancy C., Detloff, Megan R., Dutta, Satavisha, Hall, Edward D.

“…The authors present two studies that investigate the biochemical and histologic effects of the nonimmunosuppressive neuroimmunophilin (NIMM) ligand V-10,367 in…”
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