Search Results - "Detke, Holland C"

Rapid Onset of Effect of Galcanezumab for the Prevention of Episodic Migraine: Analysis of the EVOLVE Studies by Detke, Holland C., Millen, Brian A., Zhang, Qi, Samaan, Karen, Ailani, Jessica, Dodick, David W., Aurora, Sheena K.

“…Objective To evaluate onset of effect of galcanezumab in patients with episodic migraine. Background Galcanezumab is a monoclonal antibody that binds to…”
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Olanzapine/Fluoxetine Combination in Children and Adolescents With Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Trial by Detke, Holland C., PhD, DelBello, Melissa P., MD, Landry, John, MMath, Usher, Roland W., MS

“…Objective To assess the efficacy and safety of olanzapine/fluoxetine combination (OFC) for the acute treatment of bipolar depression in children and…”
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Post-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, I: analysis of cases by Detke, Holland C, McDonnell, David P, Brunner, Elizabeth, Zhao, Fangyi, Sorsaburu, Sebastian, Stefaniak, Victoria J, Corya, Sara A

“…An advance in the treatment of schizophrenia is the development of long-acting intramuscular formulations of antipsychotics, such as olanzapine long-acting…”
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Galcanezumab in chronic migraine: The randomized, double-blind, placebo-controlled REGAIN study by Detke, Holland C, Goadsby, Peter J, Wang, Shufang, Friedman, Deborah I, Selzler, Katherine J, Aurora, Sheena K

“…OBJECTIVETo evaluate the efficacy and safety of galcanezumab, a humanized monoclonal antibody that selectively binds to calcitonin gene-related peptide, in the…”
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Post-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, II: investigations of mechanism by McDonnell, David P, Detke, Holland C, Bergstrom, Richard F, Kothare, Prajakti, Johnson, Jason, Stickelmeyer, Mary, Sanchez-Felix, Manuel V, Sorsaburu, Sebastian, Mitchell, Malcolm I

“…Olanzapine long-acting injection (LAI) is a salt-based depot antipsychotic combining olanzapine and pamoic acid. The slow intramuscular dissolution of this…”
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Safety and efficacy of galcanezumab in patients for whom previous migraine preventive medication from two to four categories had failed (CONQUER): a multicentre, randomised, double-blind, placebo-controlled, phase 3b trial by Mulleners, Wim M, Kim, Byung-Kun, Láinez, Miguel J A, Lanteri-Minet, Michel, Pozo-Rosich, Patricia, Wang, Shufang, Tockhorn-Heidenreich, Antje, Aurora, Sheena K, Nichols, Russell M, Yunes-Medina, Laura, Detke, Holland C

“…Many patients who require migraine preventive treatment have not been able to tolerate or have not responded to multiple previous preventive medications. We…”
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Quality of life in children and adolescents with bipolar I depression treated with olanzapine/fluoxetine combination by Walker, Daniel J, DelBello, Melissa P, Landry, John, D'Souza, Deborah N, Detke, Holland C

“…We examined the efficacy of olanzapine/fluoxetine combination (OFC) in improving health-related quality of life (QoL) in the treatment of bipolar depression in…”
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Efficacy of olanzapine long-acting injection in patients with acutely exacerbated schizophrenia: an insight from effect size comparison with historical oral data by Detke, Holland C, Zhao, Fangyi, Witte, Michael M

“…To treat acute schizophrenia, a long-acting injectable antipsychotic needs a rapid onset of action and therapeutic profile similar to that of oral agents. The…”
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Effect of galcanezumab in women with episodic migraine meeting criteria for menstrually related migraine: A post hoc analysis of EVOLVE‐1 and EVOLVE‐2 by MacGregor, E. Anne, Okonkwo, Rose, Detke, Holland C., Polavieja, Pepa, Fernandes, Maria S., Pavlovic, Jelena M.

“…Background We evaluated galcanezumab for migraine prevention in patients who met International Classification of Headache Disorders, 3rd edition criteria for…”
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Long-term treatment with galcanezumab in patients with chronic migraine: results from the open-label extension of the REGAIN study by Pozo-Rosich, Patricia, Detke, Holland C., Wang, Shufang, Doležil, David, Li, Lily Q., Aurora, Sheena K., Reuter, Uwe

“…Galcanezumab, a monoclonal antibody to calcitonin gene-related peptide, was found to be safe and efficacious for the preventive treatment of chronic migraine…”
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Early response predicts subsequent response to olanzapine long-acting injection in a randomized, double-blind clinical trial of treatment for schizophrenia by Ascher-Svanum, Haya, Zhao, Fangyi, Detke, Holland C, Nyhuis, Allen W, Lawson, Anthony H, Stauffer, Virginia L, Montgomery, William, Witte, Michael M, McDonnell, David P

“…In patients with schizophrenia, early non-response to oral antipsychotic therapy robustly predicts subsequent non-response to continued treatment with the same…”
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Olanzapine Long-Acting Injection: A 24-Week, Randomized, Double-Blind Trial of Maintenance Treatment in Patients With Schizophrenia by Kane, John M., Detke, Holland C., Naber, Dieter, Sethuraman, Gopalan, Lin, Daniel Y., Bergstrom, Richard F., McDonnell, David

“…ObjectiveThe purpose of the present study was to evaluate the efficacy and tolerability of olanzapine long-acting injection for maintenance treatment of…”
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Safety of galcanezumab in patients with episodic migraine: A randomized placebo-controlled dose-ranging Phase 2b study by Oakes, Tina Marie Myers, Skljarevski, Vladimir, Zhang, Qi, Kielbasa, William, Hodsdon, Michael E, Detke, Holland C, Camporeale, Angelo, Saper, Joel R

“…Background Safety findings from a Phase 2b study of galcanezumab, a humanized monoclonal antibody against calcitonin gene-related peptide, for prevention of…”
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Pharmacokinetics of olanzapine long-acting injection: the clinical perspective by Heres, Stephan, Kraemer, Susanne, Bergstrom, Richard F, Detke, Holland C

“…Olanzapine long-acting injection (OLAI) is a sustained-release depot antipsychotic for the treatment of schizophrenia in adults. Our objective was to explain…”
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Approvals and indications of CGRP antibodies by Nichols, Russell, Detke, Holland C, Hundemer, Hans-Peter, Aurora, Sheena K

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Galcanezumab in Patients with Multiple Previous Migraine Preventive Medication Category Failures: Results from the Open-Label Period of the CONQUER Trial by Reuter, Uwe, Lucas, Christian, Dolezil, David, Hand, Austin L., Port, Martha D., Nichols, Russell M., Stroud, Chad, Tockhorn-Heidenreich, Antje, Detke, Holland C.

“…Introduction Results from the open-label extension of the phase 3b CONQUER trial are presented to evaluate the effectiveness and safety of galcanezumab, a…”
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Changes in migraine interictal burden following treatment with galcanezumab: Results from a phase III randomized, placebo‐controlled study by Lipton, Richard B., Buse, Dawn C., Sandoe, Claire H., Ford, Janet H., Hand, Austin L., Jedynak, Jakub P., Port, Martha D., Detke, Holland C.

“…Objective To evaluate changes in interictal burden with galcanezumab versus placebo in patients with episodic (EM) or chronic migraine (CM). Background The…”
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Long-term safety and efficacy of olanzapine long-acting injection in patients with schizophrenia or schizoaffective disorder: a 6-year, multinational, single-arm, open-label study by McDonnell, David P, Landry, John, Detke, Holland C

“…The objective of this study was to assess the long-term safety and efficacy of olanzapine long-acting injection (LAI). A 6-year, single-arm, open-label…”
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Olanzapine long-acting injection: a review of first experiences of post-injection delirium/sedation syndrome in routine clinical practice by Bushe, Chris J, Falk, Deborah, Anand, Ernie, Casillas, Marta, Perrin, Elena, Chhabra-Khanna, Rashna, Detke, Holland C

“…Olanzapine long-acting injection (LAI) for the treatment of schizophrenia was associated with a cluster of symptoms termed post-injection delirium/sedation…”
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Randomized, Placebo-Controlled Trial of Olanzapine as Maintenance Therapy in Patients With Bipolar I Disorder Responding to Acute Treatment With Olanzapine by Tohen, Mauricio, Calabrese, Joseph R., Sachs, Gary S., Banov, Michael D., Detke, Holland C., Risser, Richard, Baker, Robert W., Chou, James C.-Y., Bowden, Charles L.

“…OBJECTIVE: In a placebo-controlled, double-blind study, the authors investigated the efficacy and safety of olanzapine as monotherapy in relapse prevention in…”
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