Search Results - "Detheux, M"

3-Phosphoglycerate dehydrogenase deficiency: an inborn error of serine biosynthesis by Jaeken, J, Detheux, M, Van Maldergem, L, Foulon, M, Carchon, H, Van Schaftingen, E

“…Serine concentrations were markedly decreased in the cerebrospinal fluid of two brothers with congenital microcephaly, profound psychomotor retardation,…”
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Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9-74] Processed Variant by Vakili, Jalal, Standker, Ludger, Detheux, Michel, Vassart, Gilbert, Forssmann, Wolf-Georg, Parmentier, Marc

“…Abstract We have previously isolated from human hemofiltrate an N-terminally truncated form of the hemofiltrate CC chemokine 1 (HCC-1), and characterized…”
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Binding of sorbitol 6-phosphate and of fructose 1-phosphate to the regulatory protein of liver glucokinase by VANDERCAMMEN, A, DETHEUX, M, VAN SCHAFTINGEN, E

“…Using a binding assay in which the ligand-protein complex is separated from free ligand by precipitation with poly(ethylene glycol) 6000, we found that the…”
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Functional analysis of chemically synthesized derivatives of the human CC chemokine CCL15/HCC-2, a high affinity CCR1 ligand by Escher, S.E., Vakili, J., Forssmann, U., Frimpong-Boateng, A., Sticht, H., Detheux, M., Adermann, K.

“…:  The CCL15 is a human CC chemokine that activates the receptors, CCR1 and CCR3. Unlike other chemokines, it contains an unusually long N‐terminal domain of…”
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Multiplex IHC panel development for adenosine pathway markers and TIL in human cancer specimens by Pabois, A., Bodo, V., Boisson, A., Crosignani, S., De Henau, O., Detheux, M., Garaud, S., Lager, J., Martinoli, C., Mercier, M., Naveaux, C., Thomas, N., Wald, N., Vezzu, A., Willard-Gallo, K., Houthuys, E.

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Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation by Le Poul, Emmanuel, Loison, Cécile, Struyf, Sofie, Springael, Jean-Yves, Lannoy, Vincent, Decobecq, Marie-Eve, Brezillon, Stéphane, Dupriez, Vincent, Vassart, Gilbert, Van Damme, Jo, Parmentier, Marc, Detheux, Michel

“…Short chain fatty acids (SCFAs), including acetate, propionate, and butyrate, are produced at high concentration by bacteria in the gut and subsequently…”
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Effect of sulphur mustard on the expression of urokinase in cultured 3T3 fibroblasts by DETHEUX, M, JIJAKLI, H, LISON, D

“…The expression of plasminogen activator (PA), a serine proteinase involved in the degradation of extracellular matrix proteins, has been investigated in 3T3…”
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Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids by Wittamer, Valérie, Franssen, Jean-Denis, Vulcano, Marisa, Mirjolet, Jean-François, Le Poul, Emmanuel, Migeotte, Isabelle, Brézillon, Stéphane, Tyldesley, Richard, Blanpain, Cédric, Detheux, Michel, Mantovani, Alberto, Sozzani, Silvano, Vassart, Gilbert, Parmentier, Marc, Communi, David

“…Dendritic cells (DCs) and macrophages are professional antigen-presenting cells (APCs) that play key roles in both innate and adaptive immunity. ChemR23 is an…”
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The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54 by Kotani, Masato, Detheux, Michel, Vandenbogaerde, Ann, Communi, David, Vanderwinden, Jean-Marie, Le Poul, Emmanuel, Brézillon, Stéphane, Tyldesley, Richard, Suarez-Huerta, Nathalie, Vandeput, Fabrice, Blanpain, Cédric, Schiffmann, Serge N., Vassart, Gilbert, Parmentier, Marc

“…Natural peptides displaying agonist activity on the orphan G protein-coupled receptor GPR54 were isolated from human placenta. These 54-, 14,- and 13-amino…”
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Identification of a novel human ADP receptor coupled to G(i) by Communi, D, Gonzalez, N S, Detheux, M, Brézillon, S, Lannoy, V, Parmentier, M, Boeynaems, J M

“…We have cloned and expressed a novel human G-protein-coupled receptor closely related to the human P2Y(12) receptor. It corresponds to the orphan receptor…”
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Vasopressin-like peptide and its receptor function in an indirect diuretic signaling pathway in the red flour beetle by Aikins, Michael J., Schooley, David A., Begum, Khurshida, Detheux, Michel, Beeman, Richard W., Park, Yoonseong

“…The insect arginine vasopressin-like (AVPL) peptide is of special interest because of its potential function in the regulation of diuresis. Genome sequences of…”
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Distinct recognition of OX1 and OX2 receptors by orexin peptides by Ammoun, Sylwia, Holmqvist, Tomas, Shariatmadari, Ramin, Oonk, Hendrica B, Detheux, Michel, Parmentier, Marc, Akerman, Karl E O, Kukkonen, Jyrki P

“…In this study, we have compared the abilities of orexin-A and orexin-B and variants of orexin-A to activate different Ca(2+) responses (influx and release) in…”
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3-phosphoglycerate dehydrogenase deficiency and 3-phosphoserine phosphatase deficiency : Inborn errors of serine biosynthesis by JAEKEN, J, DETHEUX, M, VAN MALDERGEM, L, FRIJNS, J. P, ALLIET, P, FOULON, M, CARCHON, H, VAN SCHAFTINGEN, E

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Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties by Proost, Paul, Schutyser, Evemie, Menten, Patricia, Struyf, Sofie, Wuyts, Anja, Opdenakker, Ghislain, Detheux, Michel, Parmentier, Marc, Durinx, Christine, Lambeir, Anne-Marie, Neyts, Johan, Liekens, Sandra, Maudgal, Prabhat C., Billiau, Alfons, Van Damme, Jo

“…The interferon (IFN)–inducible chemokines, specifically, IFN-γ–inducible protein-10 (IP-10), monokine induced by IFN-γ (Mig), and IFN-inducible T-cell…”
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Identification and characterization of an endogenous chemotactic ligand specific for FPRL2 by Migeotte, Isabelle, Riboldi, Elena, Franssen, Jean-Denis, Grégoire, Françoise, Loison, Cécile, Wittamer, Valérie, Detheux, Michel, Robberecht, Patrick, Costagliola, Sabine, Vassart, Gilbert, Sozzani, Silvano, Parmentier, Marc, Communi, David

“…Chemotaxis of dendritic cells (DCs) and monocytes is a key step in the initiation of an adequate immune response. Formyl peptide receptor (FPR) and FPR-like…”
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Identification of Natural Ligands for the Orphan G Protein-coupled Receptors GPR7 and GPR8 by Brezillon, Stéphane, Lannoy, Vincent, Franssen, Jean-Denis, Le Poul, Emmanuel, Dupriez, Vincent, Lucchetti, Jean, Detheux, Michel, Parmentier, Marc

“…GPR7 and GPR8 are two structurally related orphan G protein-coupled receptors, presenting high similarities with opioid and somatostatin receptors. Two…”
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Search for a third susceptibility gene for maturity-onset diabetes of the young. Studies with eleven candidate genes by M Vaxillaire, N Vionnet, C Vigouroux, F Sun, R Espinosa, 3rd, M M Lebeau, M Stoffel, M Lehto, J S Beckmann, M Detheux

“…Search for a third susceptibility gene for maturity-onset diabetes of the young. Studies with eleven candidate genes. M Vaxillaire , N Vionnet , C Vigouroux ,…”
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The Orexin OX1 Receptor Activates a Novel Ca2+ Influx Pathway Necessary for Coupling to Phospholipase C by Lund, Per-Eric, Shariatmadari, Ramin, Uustare, Ain, Detheux, Michel, Parmentier, Marc, Kukkonen, Jyrki P., Åkerman, Karl E.O.

“…Ca2+ elevations in Chinese hamster ovary cells stably expressing OX1 receptors were measured using fluorescent Ca2+ indicators fura-2 and fluo-3. Stimulation…”
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Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties by Detheux, M, Ständker, L, Vakili, J, Münch, J, Forssmann, U, Adermann, K, Pöhlmann, S, Vassart, G, Kirchhoff, F, Parmentier, M, Forssmann, W G

“…Hemofiltrate CC chemokine (HCC)-1 is a recently described human chemokine that is constitutively expressed in numerous tissues and is present at high…”
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Functional characterization of a human receptor for neuropeptide FF and related peptides by Kotani, Masato, Mollereau, Catherine, Detheux, Michel, Le Poul, Emmanuel, Brézillon, Stéphane, Vakili, Jalal, Mazarguil, Honoré, Vassart, Gilbert, Zajac, Jean‐Marie, Parmentier, Marc

“…Neuropeptides FF (NPFF) and AF (NPAF) are involved in pain modulation and opioid tolerance. These peptides were known to act through uncharacterized G…”
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