Search Results - "Deters, Kacie D"
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Representativeness of samples enrolled in Alzheimer's disease research centers
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-04-2023)“…To generalize findings on the mechanisms and prognosis in Alzheimer's disease and related dementias (ADRD), it is critical for ADRD research to be…”
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Donanemab for Alzheimer Disease—Who Benefits and Who Is Harmed?
Published in JAMA : the journal of the American Medical Association (08-08-2023)“…Availability of safe and effective treatments for Alzheimer disease is an urgent challenge given the global shift toward an older population and increased risk…”
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Association of Short and Long Sleep Duration With Amyloid-β Burden and Cognition in Aging
Published in JAMA neurology (01-10-2021)“…Disrupted sleep is common in aging and is associated with cognition. Age-related changes to sleep are associated with multiple causes, including early…”
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Amyloid PET Imaging in Self-Identified Non-Hispanic Black Participants of the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study
Published in Neurology (16-03-2021)“…To examine whether amyloid PET in cognitively normal (CN) individuals screened for the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) study differed…”
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Inclusion of Underrepresented Groups in Preclinical Alzheimer Disease Trials-Opportunities Abound
Published in JAMA network open (01-07-2021)Get full text
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Subjective cognitive decline across ethnoracial groups in the A4 study
Published in Alzheimer's & dementia (01-09-2023)“…INTRODUCTION The associations between subjective cognitive decline (SCD), cognition, and amyloid were explored across diverse participants in the A4 study…”
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A simple genetic stratification method for lower cost, more expedient clinical trials in early Alzheimer's disease: A preliminary study of tau PET and cognitive outcomes
Published in Alzheimer's & dementia (01-07-2023)“…Introduction Identifying individuals who are most likely to accumulate tau and exhibit cognitive decline is critical for Alzheimer's disease (AD) clinical…”
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TOMM40‐APOE haplotypes are associated with cognitive decline in non‐demented Blacks
Published in Alzheimer's & dementia (01-08-2021)“…Introduction The goal was to investigate effects of APOE‐TOMM40‐‘523 haplotypes on cognitive decline in non‐demented non‐Hispanic Blacks (NHB), and determine…”
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Loneliness, cerebrovascular and Alzheimer's disease pathology, and cognition
Published in Alzheimer's & dementia (01-10-2024)“…INTRODUCTION Loneliness has a rising public health impact, but research involving neuropathology and representative cohorts has been limited. METHODS Inverse…”
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Identification of Sex-Specific Genetic Variants Associated With Tau PET
Published in Neurology. Genetics (01-12-2022)“…Important sex differences exist in tau pathology along the Alzheimer disease (AD) continuum, with women showing enhanced tau deposition compared with men,…”
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Riding the merry-go-round of racial disparities in ADRD research
Published in Alzheimer's & dementia (01-10-2023)“…With the rapid expansion of the aging population, the burden of Alzheimer's disease related dementias (ADRD) is anticipated to increase in racialized and…”
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Exercise: Just What the Doctor Ordered, But Why? Elucidating Mechanisms for Women’s Increased High-Density Lipoprotein Benefit From Exercise and for the Health ABC Study
Published in Journal of applied gerontology (01-12-2024)“…High-density lipoprotein (HDL) is protective against cardiovascular disease. Exercise can increase HDL concentration, and some evidence suggests that this…”
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KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers
Published in Neurobiology of aging (01-05-2021)“…KLOTHO∗VS heterozygosity (KL∗VSHET+) was recently shown to be associated with reduced risk of Alzheimer’s disease (AD) in APOE∗4 carriers. Additional studies…”
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Genome-wide association study of language performance in Alzheimer’s disease
Published in Brain and language (01-09-2017)“…•We identified novel genetic variants associated with language performance.•Minor allele variants in GLI3 are associated with worse language…”
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Loneliness predicts stronger negative associations between cerebrovascular, but not Alzheimer’s, pathology and cognition
Published in Alzheimer's & dementia (01-12-2022)“…Background Alzheimer’s disease (AD) and cerebrovascular disease are the two most common pathologies underlying dementia. Loneliness is associated with faster…”
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[(11)C]PiB PET in Gerstmann-Sträussler-Scheinker disease
Published in American journal of nuclear medicine and molecular imaging (01-01-2016)“…Gerstmann-Sträussler-Scheinker Disease (GSS) is a familial neurodegenerative disorder characterized clinically by ataxia, parkinsonism, and dementia, and…”
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Cerebral hypometabolism and grey matter density in MAPT intron 10 +3 mutation carriers
Published in American journal of neurodegenerative disease (2014)“…Multiple systems tauopathy with presenile dementia (MSTD), a form of frontotemporal dementia with parkinsonism-17 with tau inclusions (FTDP-17T), is a…”
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Amygdala tau in preclinical Alzheimer’s disease: Neuroimaging / Normal brain aging
Published in Alzheimer's & dementia (01-12-2020)Get full text
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Amygdala tau in preclinical Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2020)“…Background Post‐mortem and neuroimaging studies have established the amygdala as one of the earliest sites of tau deposition and neurofibrillary tangles. We…”
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Identification of sex‐specific genetic variants associated with tau‐PET
Published in Alzheimer's & dementia (01-12-2022)“…Background Abnormal tau deposition is an important pathological feature of AD. Important sex differences exist, with women showing greater tau deposition along…”
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