Search Results - "Deswal, Laxmi"
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Synthesis, antimicrobial and α-glucosidase inhibition of new benzimidazole-1,2,3-triazole-indoline derivatives: a combined experimental and computational venture
Published in Chemical papers (01-12-2022)“…In the current research work, a new series of benzimidazole-1,2,3-triazole-indoline derivatives ( 5a–r ) were designed and synthesized by employing click…”
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Benzimidazole-1,2,3-triazole-piperazine hybrids: design, synthesis, antidiabetic evaluation and molecular modelling studies
Published in Research on chemical intermediates (01-03-2023)“…Sixteen new benzimidazole hybrids containing 1,2,3-triazole and piperazine scaffolds have been synthesized by click reaction. The synthesized hybrids were…”
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Metal Complexes of 1,2,4-Triazole Based Ligand: Synthesis, Structural Elucidation, DFT Calculations, Alpha-Amylase and Alpha-Glucosidase Inhibitory Activity Along with Molecular Docking Studies
Published in Journal of inorganic and organometallic polymers and materials (2024)“…In search of 1,2,4-triazole-based antidiabetic agents, new mixed-ligand chelates of the type, [M(L)(H 2 O) 3 ] (where M = Co(II), Ni(II), Cu(II) and Zn(II)),…”
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Facile synthesis, antimicrobial evaluation and molecular docking studies of pyrazole-imidazole-triazole hybrids
Published in Journal of molecular structure (05-01-2021)“…•Regioselective synthesis of 1,4-disubstituted imidazole-pyrazole-triazole hybrids by using click chemistry.•The compound 6m demonstrated excellent potency for…”
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Pyrazolyl-Imidazole clubbed 1,2,3-triazoles: Synthesis, structure explication and antimicrobial evaluation
Published in Journal of molecular structure (15-08-2022)“…•Pyrazolyl-imidazole-triazole hybrids (3a-3r) has been designed and synthesized•The hybrids were characterized by IR, 1H, 13C NMR, HRMS and X-ray…”
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Development of novel anti-infective and antioxidant azole hybrids using a wet and dry approach
Published in Future medicinal chemistry (01-06-2021)“…Considering emerging drug resistance in microbes, this work is focused on the synthesis of azole hybrids as novel antimicrobials. The triazole derivatives…”
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Instigating the in vitro antidiabetic activity of new tridentate Schiff base ligand appended M(II) complexes: From synthesis, structural characterization, quantum computational calculations to molecular docking, and molecular dynamics simulation studies
Published in Applied organometallic chemistry (01-04-2023)“…In search of novel medications that could be effective in preventing and treating diabetes, four new [Co(L)(H2O)3] (2), [Ni(L)(H2O)3] (3), [Cu(L)(H2O)] (4) and…”
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Synthesis and antidiabetic evaluation of benzimidazole‐tethered 1,2,3‐triazoles
Published in Archiv der Pharmazie (Weinheim) (01-09-2020)“…Some novel benzimidazole‐tethered 1,2,3‐triazole derivatives (4a–r) were synthesized by a click reaction between 2‐substituted…”
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Cobalt(II), nickel(II), copper(II) and zinc(II) complexes of thiadiazole based Schiff base ligands: Synthesis, structural characterization, DFT, antidiabetic and molecular docking studies
Published in Journal of molecular structure (05-04-2022)“…•New Co(II), Ni(II), Cu(II), Zn(II) complexes were synthesized using tridentate Schiff base ligands.•Characterization of synthesized compounds was done using…”
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Synthesis and evaluation of novel pyrazole-imidazole hybrids as antimicrobial candidates
Published in Synthetic communications (17-09-2021)“…The present study describes a facile and efficient synthesis of 1-(N-arylacetamide)-4-phenyl-2-pyrazolyl-imidazole 7a-7t by reacting…”
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