Search Results - "Dessein, Hélia"
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Genetic algorithms identify individuals with high risk of severe liver disease caused by schistosomes
Published in Human genetics (01-06-2020)“…Schistosomes induce severe hepatic disease, which is fatal in 2–10% of cases, mortality being higher in cases of co-infection with HBV or HCV. Hepatic disease…”
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Correction to: Genetic algorithms identify individuals with high risk of severe liver disease caused by schistosomes
Published in Human genetics (01-06-2020)“…In the original article publication, the affiliation of the author Ana Coutinho is incorrect…”
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Liver ultrasound elastography for the evaluation of periportal fibrosis in schistosomiasis mansoni: A cross-sectional study
Published in PLoS neglected tropical diseases (01-11-2018)“…ARFI elastrography has been used as a noninvasive method to assess the severity of liver fibrosis in viral hepatitis, although with few studies in…”
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FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly
Published in PLoS neglected tropical diseases (01-01-2016)“…Schistosoma eggs cause chronic liver inflammation and a complex disease characterized by hepatic fibrosis (HF) and splenomegaly (SplM). FOXP3+ Tregs could…”
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Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis
Published in The Journal of immunology (1950) (01-05-2008)“…In populations exposed to Leishmania braziliensis, certain subjects develop skin ulcers, whereas others are naturally protected against cutaneous…”
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IL2RA genetic variants reduce IL-2-dependent responses and aggravate human cutaneous leishmaniasis
Published in The Journal of immunology (1950) (15-03-2015)“…The outcome of Leishmania infections varies substantially, depending on the host and the parasite strain; infection may be asymptomatic or cause mild or severe…”
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The IL17F and IL17RA Genetic Variants Increase Risk of Cerebral Malaria in Two African Populations
Published in Infection and immunity (01-02-2016)“…Cerebral malaria (CM) is a neurological complication of infection with Plasmodium falciparum that is partly caused by cytokine-mediated inflammation. It is not…”
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A Functional IL22 Polymorphism (rs2227473) Is Associated with Predisposition to Childhood Cerebral Malaria
Published in Scientific reports (31-01-2017)“…Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection. This encephalopathy is characterized by coma and is thought to result from…”
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Cytokine regulation of periportal fibrosis in humans infected with Schistosoma mansoni: IFN-gamma is associated with protection against fibrosis and TNF-alpha with aggravation of disease
Published in The Journal of immunology (1950) (15-07-2002)“…Hepatic periportal fibrosis, which affects 5-10% of subjects infected by Schistosoma mansoni, is caused by the T cell-dependent granuloma that develop around…”
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Improved technique that allows the performance of large-scale SNP genotyping on DNA immobilized by FTA ® technology
Published in Infection, genetics and evolution (2007)“…FTA ® technology is a novel method designed to simplify the collection, shipment, archiving and purification of nucleic acids from a wide variety of biological…”
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IL‐22 and IL‐22 binding protein (IL‐22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections
Published in Hepatology (Baltimore, Md.) (01-04-2015)“…Interleukin (IL)‐22 acts on epithelia, hepatocytes, and pancreatic cells and stimulates innate immunity, tissue protection, and repair. IL‐22 may also cause…”
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Genetic Control of Schistosome Infections by the SM1 Locus of the 5q31-q33 Region Is Linked to Differentiation of Type 2 Helper T Lymphocytes
Published in Infection and Immunity (01-09-1999)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis
Published in Scientific reports (03-12-2018)“…Severe Malarial Anemia (SMA), a life-threatening childhood Plasmodium falciparum malaria syndrome requiring urgent blood transfusion, exhibits inflammatory and…”
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Potential Use of Interleukin-10 Blockade as a Therapeutic Strategy in Human Cutaneous Leishmaniasis
Published in Journal of immunology research (01-01-2015)“…Interleukin-10 overproduction has been associated with worse prognosis in human cutaneous leishmaniasis, while IFN-γ-dependent responses are associated with…”
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Correction: In Vivo MRI Assessment of Hepatic and Splenic Disease in a Murine Model of Schistosmiasis
Published in PLoS neglected tropical diseases (01-10-2015)Get full text
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In Vivo MRI Assessment of Hepatic and Splenic Disease in a Murine Model of Schistosomiasis [corrected]
Published in PLoS neglected tropical diseases (01-09-2015)“…Schistosomiasis (or bilharzia), a major parasitic disease, affects more than 260 million people worldwide. In chronic cases of intestinal schistosomiasis…”
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IL-22 and IL-22 binding protein (IL-22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections (CCR4P.202)
Published in The Journal of immunology (1950) (01-05-2015)“…Abstract IL-22 acts on epithelia, hepatocytes and pancreatic cells and stimulates innate immunity, tissue protection and repair. IL-22 may also cause…”
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FOXP3 + Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum : The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly: e0004306
Published in PLoS neglected tropical diseases (01-01-2016)“…Schistosoma eggs cause chronic liver inflammation and a complex disease characterized by hepatic fibrosis (HF) and splenomegaly (SplM). FOXP3+ Tregs could…”
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Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33
Published in Nature genetics (01-10-1996)“…Three hundred million individuals are at risk of infection by schistosomes and around 200,000 die each year of this disease. Severe clinical disease in…”
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