Search Results - "Desrosiers, Gretchen"

Sleep-loss activates NLRP3 inflammasome-activity in astrocytes by increasing electroencephalogram slow-waves and activates microglia to increase NREM sleep amounts by Zielinski, Mark R, Prabhala, Rao H, Niznikiewicz, Madaleine M, Desrosiers, Gretchen

“…We previously found that NLRP3 inflammasome activity is a critical mechanism regulating sleep and slow-waves. Microglia and astrocytes play a major role in…”
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0219 Mice Lacking IL-18 have Reduced Sleep and Slow-waveActivityResponses to Sleep Promoting Stimuli by Zielinski, Mark R, Gerashchenko, Dmitry, Patel, Dhruviben, Torres, Kayla, Desrosiers, Gretchen

“…Introduction Interleukin (IL)-18 is a pro-inflammatory cytokine that is a member of the IL-1 family. IL-18 is activated by inflammatory stimuli including the…”
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0017 Multiple Types of Pathogen-Associated Molecular Patterns Activate Different Types of Inflammasomes Through Caspase-1 to Alter Sleep and Slow-wave Activity by Zielinski, Mark R, Gerashchenko, Dmitry, Torres, Kayla, Patel, Dhruviben, Desrosiers, Gretchen

“…Introduction Inflammasomes are protein complexes that are activated by specific pathogen-associated molecular patterns (PAMPs) through corresponding pattern…”
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