Search Results - "Desrochers, Linda P"

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  1. 1

    Stereospecific Metabolism of R - and S -Warfarin by Human Hepatic Cytosolic Reductases by Barnette, Dustyn A, Johnson, Bryce P, Pouncey, Dakota L, Nshimiyimana, Robert, Desrochers, Linda P, Goodwin, Thomas E, Miller, Grover P

    Published in Drug metabolism and disposition (01-09-2017)
    “…Coumadin (rac-warfarin) is the most commonly used anticoagulant in the world; however, its clinical use is often challenging because of its narrow therapeutic…”
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    Journal Article
  2. 2

    Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells by Caro, Andres A., Commissariat, Ava, Dunn, Caroline, Kim, Hyunjoo, García, Salvador Lorente, Smith, Allen, Strang, Harrison, Stuppy, Jake, Desrochers, Linda P., Goodwin, Thomas E.

    Published in Biochimica et biophysica acta (01-11-2015)
    “…Salicylaldehyde isonicotinoyl hydrazone (SIH) is an iron chelator of the aroylhydrazone class that displays antioxidant or prooxidant effects in different…”
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    Journal Article
  3. 3

    Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites by Preston Pugh, C., Pouncey, Dakota L., Hartman, Jessica H., Nshimiyimana, Robert, Desrochers, Linda P., Goodwin, Thomas E., Boysen, Gunnar, Miller, Grover P.

    Published in Archives of biochemistry and biophysics (15-12-2014)
    “…[Display omitted] •Synthesis of R- and S-7-hydroxywarfarin through green chemistry.•Two novel 7-hydroxywarfarin glucuronides generated by microsomal hepatic…”
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    Journal Article