Search Results - "Despa, F"
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Endoplasmic Reticulum Overcrowding as a Mechanism of β-Cell Dysfunction in Diabetes
Published in Biophysical journal (21-04-2010)“…This study suggests a molecular mechanism that explains the accumulation of denaturated proinsulin in the endoplasmic reticulum (ER) of β-cells. Such states…”
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Dilation of the endoplasmic reticulum in beta cells due to molecular overcrowding? Kinetic simulations of extension limits and consequences on proinsulin synthesis
Published in Biophysical chemistry (01-03-2009)“…Insulin regulates the energy homeostasis of the human body. This is synthesized in the endoplasmic reticulum (ER) of pancreatic beta cells from proinsulin…”
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Hydrophobe-Water Interactions: Methane as a Model
Published in Biophysical journal (01-11-2008)“…Recent molecular-dynamics simulations have demonstrated that the use of an empirical hydrophobic potential displaying two minima, i.e., one for hydrophobes in…”
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The relative thermal stability of tissue macromolecules and cellular structure in burn injury
Published in Burns (01-08-2005)“…When tissue is subjected to higher than physiological temperatures, protein and cell organelle structures can be altered resulting in cell death and subsequent…”
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5
Amyloid Oligomer Formation Probed by Water Proton Magnetic Resonance Spectroscopy
Published in Biophysical journal (04-05-2011)“…Formation of amyloid oligomers, the most toxic species of amyloids in degenerative diseases, is critically coupled to the interplay with surrounding water. The…”
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Cholic acid micelles--controlling the size of the aqueous cavity by PEGylation
Published in Physical chemistry chemical physics : PCCP (01-01-2010)“…Data show that cholic acid (CA) micelles are less densely packed and much smaller than micelles formed by typical surfactants, suggesting that CA derivatives…”
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Two-step liquid drop model for binary, metal-rich clusters
Published in Physics letters. A (30-10-2000)“…It is shown that differences observed between the ionization potentials of the molecular-doped metallic clusters and those corresponding to the bare metallic…”
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Endoplasmic Reticulum Overcrowding as a Mechanism of [Beta]-Cell Dysfunction in Diabetes
Published in Biophysical journal (21-04-2010)“…This study suggests a molecular mechanism that explains the accumulation of denaturated proinsulin in the endoplasmic reticulum (ER) of β-cells. Such states…”
Get full text
Journal Article -
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Inter-basin dynamics on multidimensional potential surfaces: Kinetic traps
Published in The European physical journal. D, Atomic, molecular and optical physics (Print) (01-06-2003)Get full text
Conference Proceeding -
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Interpretive approach to collective effects of electrons in multicenter problems
Published in The European physical journal. D, Atomic, molecular and optical physics (Print) (01-06-2003)Get full text
Conference Proceeding Journal Article -
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On the doublet formation in the flocculation process of the yeast cells
Published in BioSystems (01-08-2000)“…The combination of single cells to form doublets is regarded as the rate-limiting step of flocculation and requires the presence of surface proteins in active…”
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Dilation of the endoplasmic reticulum in beta cells due to molecular overcrowding?
Published in Biophysical chemistry (01-03-2009)“…Insulin regulates the energy homeostasis of the human body. This is synthesized in the endoplasmic reticulum (ER) of pancreatic beta cells from proinsulin…”
Get full text
Journal Article -
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The influence of O and C doping on the ionization potentials of Li-clusters
Published in The European physical journal. D, Atomic, molecular, and optical physics (01-09-2000)Get full text
Journal Article -
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On the geometrical factor in the off-centre diffusion
Published in The Journal of physics and chemistry of solids (01-09-1996)“…The geometrical factor of the off-centre diffusion coefficient is computed for certain two- and three-dimensional cubic lattices, and a method for estimating…”
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The one-dimensional model of the off-centre potential of the fluorine ion in the NaBr lattice
Published in Journal of materials science letters (15-01-1996)Get full text
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A note on off-centre diffusion
Published in Solid state communications (01-04-1995)“…Within a one-dimensional model of off-centre diffusion it is shown that the diffusion coefficient depends on the number of off-centre sites and on their…”
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Dielectric modulation of biological water
Published in Physical review letters (26-11-2004)“…We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of…”
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