Search Results - "Despa, F"

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  1. 1

    Endoplasmic Reticulum Overcrowding as a Mechanism of β-Cell Dysfunction in Diabetes by Despa, F.

    Published in Biophysical journal (21-04-2010)
    “…This study suggests a molecular mechanism that explains the accumulation of denaturated proinsulin in the endoplasmic reticulum (ER) of β-cells. Such states…”
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    Journal Article
  2. 2

    Dilation of the endoplasmic reticulum in beta cells due to molecular overcrowding? Kinetic simulations of extension limits and consequences on proinsulin synthesis by Despa, F

    Published in Biophysical chemistry (01-03-2009)
    “…Insulin regulates the energy homeostasis of the human body. This is synthesized in the endoplasmic reticulum (ER) of pancreatic beta cells from proinsulin…”
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    Journal Article
  3. 3

    Hydrophobe-Water Interactions: Methane as a Model by Despa, F., Berry, R.S.

    Published in Biophysical journal (01-11-2008)
    “…Recent molecular-dynamics simulations have demonstrated that the use of an empirical hydrophobic potential displaying two minima, i.e., one for hydrophobes in…”
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  4. 4

    The relative thermal stability of tissue macromolecules and cellular structure in burn injury by Despa, F., Orgill, D.P., Neuwalder, J., Lee, R.C.

    Published in Burns (01-08-2005)
    “…When tissue is subjected to higher than physiological temperatures, protein and cell organelle structures can be altered resulting in cell death and subsequent…”
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  5. 5

    Amyloid Oligomer Formation Probed by Water Proton Magnetic Resonance Spectroscopy by Walton, J.H., Berry, R.S., Despa, F.

    Published in Biophysical journal (04-05-2011)
    “…Formation of amyloid oligomers, the most toxic species of amyloids in degenerative diseases, is critically coupled to the interplay with surrounding water. The…”
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  6. 6

    Cholic acid micelles--controlling the size of the aqueous cavity by PEGylation by Despa, F, Luo, J T, Li, J, Duan, Y, Lam, K S

    Published in Physical chemistry chemical physics : PCCP (01-01-2010)
    “…Data show that cholic acid (CA) micelles are less densely packed and much smaller than micelles formed by typical surfactants, suggesting that CA derivatives…”
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  7. 7

    Two-step liquid drop model for binary, metal-rich clusters by Despa, F

    Published in Physics letters. A (30-10-2000)
    “…It is shown that differences observed between the ionization potentials of the molecular-doped metallic clusters and those corresponding to the bare metallic…”
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    Endoplasmic Reticulum Overcrowding as a Mechanism of [Beta]-Cell Dysfunction in Diabetes by Despa, F

    Published in Biophysical journal (21-04-2010)
    “…This study suggests a molecular mechanism that explains the accumulation of denaturated proinsulin in the endoplasmic reticulum (ER) of β-cells. Such states…”
    Get full text
    Journal Article
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    On the doublet formation in the flocculation process of the yeast cells by Stan, S, Despa, F

    Published in BioSystems (01-08-2000)
    “…The combination of single cells to form doublets is regarded as the rate-limiting step of flocculation and requires the presence of surface proteins in active…”
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    Dilation of the endoplasmic reticulum in beta cells due to molecular overcrowding? by Despa, F.

    Published in Biophysical chemistry (01-03-2009)
    “…Insulin regulates the energy homeostasis of the human body. This is synthesized in the endoplasmic reticulum (ER) of pancreatic beta cells from proinsulin…”
    Get full text
    Journal Article
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    On the geometrical factor in the off-centre diffusion by Despa, F., Apostol, M.

    “…The geometrical factor of the off-centre diffusion coefficient is computed for certain two- and three-dimensional cubic lattices, and a method for estimating…”
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    A note on off-centre diffusion by Despa, F., Apostol, M.

    Published in Solid state communications (01-04-1995)
    “…Within a one-dimensional model of off-centre diffusion it is shown that the diffusion coefficient depends on the number of off-centre sites and on their…”
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  20. 20

    Dielectric modulation of biological water by Despa, Florin, Fernández, Ariel, Berry, R Stephen

    Published in Physical review letters (26-11-2004)
    “…We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of…”
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