Search Results - "Desnoyer, Jill"
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569 A novel microbiome-derived peptide reverses resistance to anti-PD-1 therapy
Published in Journal for immunotherapy of cancer (01-11-2021)“…BackgroundDespite the unprecedented clinical success of immune checkpoint therapy (ICI) in many cancers there is still a large unmet need since many patients…”
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Tu1516: IDENTIFICATION AND DEVELOPMENT OF A 1ST IN CLASS NATURALLYDERIVED PROTEIN THAT DRIVES MUCOSAL HEALING AND IS ORALLY DELIVERED BY AN ENGINEERED CELLULAR THERAPY TARGETING THE GASTRO-INTESTINAL TRACT
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2022)Get full text
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SELECTION OF MICROBIOME-DERIVED PEPTIDES THROUGH MULTI-TECHNOLOGY META-ANALYSIS, BINDING, AND FUNCTIONAL ASSAYS, IDENTIFIES PEPTIDES WITH THERAPEUTIC POTENTIAL THAT MODULATE IMMUNE RESPONSES AND DISEASE
Published in Inflammatory bowel diseases (22-01-2022)“…Abstract Microbiome-driven drug discovery holds great promise for therapeutic development. However, identification of disease-associated microbiome-host…”
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A NOVEL MICROBIALLY-DERIVED PROTEIN CAN BE EXPRESSED IN LACTOCOCCUS LACTIS AND DELIVERED ORALLY TO IMPROVE GUT BARRIER FUNCTION AND PREVENT FIBROGENESIS BY INTERACTING WITH THE EXTRACELLULAR MATRIX DURING GI INJURY
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2022)Get full text
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A NOVEL MICROBIALLY-DERIVED PROTEIN CAN BE EXPRESSED IN LACTOCOCCUS LACTIS AND DELIVERED ORALLY TO IMPROVE GUT BARRIER FUNCTION AND PREVENT FIBROGENESIS BY INTERACTING WITH THE EXTRACELLULAR MATRIX DURING GI INJURY
Published in Inflammatory bowel diseases (22-01-2022)“…Abstract Intestinal barrier dysfunction or the loss of the epithelial integrity allowing the permeation of microorganisms, dietary antigens and other particles…”
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Enduring attentional deficits in rats treated with a peripheral nerve injury
Published in Behavioural brain research (01-06-2015)“…•Rats prepared with spared nerve injury (SNI) as model of neuropathic pain.•Rats evaluated daily for 3 months post surgery for food motivation (PR schedule) or…”
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Abstract PR08: Novel microbiome-derived peptides modulate immune cell activity and the tumor microenvironment
Published in Cancer research (Chicago, Ill.) (15-04-2020)“…Abstract The gut microbiota has emerged as an important player in cancer pathology, and increasing evidence supports its role in clinical response to immune…”
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Characterization of the 5‐HT2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet‐induced obesity
Published in Pharmacology research & perspectives (01-02-2015)“…The 5‐HT2C receptor agonist lorcaserin (Belviq®) has been Food and Drug Administration (FDA) approved for the treatment of obesity. The present study is a back…”
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Characterization of the 5‐HT 2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet‐induced obesity
Published in Pharmacology research & perspectives (01-02-2015)“…Abstract The 5‐ HT 2C receptor agonist lorcaserin (Belviq ® ) has been Food and Drug Administration (FDA) approved for the treatment of obesity. The present…”
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