Search Results - "Desmots, Fabienne"
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Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P-Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases
Published in Clinical cancer research (01-05-2017)“…mutations, notably the recurrent gain-of-function L265P variant, are a distinguishing feature of activated B-cell like (ABC) diffuse large B-cell lymphoma…”
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Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study
Published in Clinical cancer research (15-06-2016)“…Next-generation sequencing (NGS) has detailed the genomic characterization of diffuse large B-cell lymphoma (DLBCL) by identifying recurrent somatic mutations…”
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BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-2014)“…Autophagy is regulated by posttranslational modifications, including acetylation. Here we show that HLA-B—associated transcript 3 (BAT3) is essential for basal…”
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Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation
Published in Frontiers in immunology (02-12-2021)“…B cell affinity maturation occurs in the germinal center (GC). Light-zone (LZ) GC B cells (B -cells) interact with follicular dendritic cells (FDCs) and…”
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Somatic mutations of cell-free circulating DNA detected by next-generation sequencing reflect the genetic changes in both germinal center B-cell-like and activated B-cell-like diffuse large B-cell lymphomas at the time of diagnosis
Published in Haematologica (Roma) (01-07-2015)Get full text
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Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells
Published in Blood (10-06-2021)“…Distinguishing chronic lymphoproliferative disorders of NK cells (CLPD-NK) from reactive NK-cell expansion is challenging. We assessed the value of killer…”
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Scythe Regulates Apoptosis-inducing Factor Stability during Endoplasmic Reticulum Stress-induced Apoptosis
Published in The Journal of biological chemistry (08-02-2008)“…Scythe (BAT3; HLA-Bassociated transcript 3, Bag 6) is a protein that has been implicated in apoptosis because it can modulate the Drosophila melanogaster…”
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The Negative Influence of Baseline Cell-free DNA on Long-term Survival in DLBCL Depends on Frontline Treatment Intensity
Published in Clinical cancer research (13-06-2023)“…This study aims to investigate the relationship between the intensity of the initial treatment given to patients with de novo diffuse large B-cell lymphoma…”
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The Reaper-Binding Protein Scythe Modulates Apoptosis and Proliferation during Mammalian Development
Published in Molecular and Cellular Biology (01-12-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Plasmablasts derive from CD23– activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction
Published in Blood (04-03-2021)“…The terminal differentiation of B cells into antibody-secreting cells (ASCs) is a critical component of adaptive immune responses. However, it is a very…”
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Immunohistological Analysis of Glutathione Transferase A4 Distribution in Several Human Tissues Using a Specific Polyclonal Antibody
Published in The journal of histochemistry and cytochemistry (01-12-2001)“…We examined the cellular distribution of glutathione transferase A4 (GSTA4) in various human tissues by indirect immunoperoxidase using a specific polyclonal…”
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Combined Stimulation with the Tumor Necrosis Factor α and the Epidermal Growth Factor Promotes the Proliferation of Hepatocytes in Rat Liver Cultured Slices
Published in International journal of hepatology (New York) (01-01-2012)“…The culture liver slices are mainly used to investigate drug metabolism and xenobiotic-mediated liver injuries while apoptosis and proliferation remain…”
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Genomic organization, 5'-flanking region and chromosomal localization of the human glutathione transferase A4 gene
Published in Biochemical journal (01-12-1998)“…We have isolated and characterized a human glutathione transferase A4 (hGSTA4) subunit gene from a yeast artificial chromosome containing several other…”
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Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma
Published in Clinical cancer research (15-01-2019)“…Follicular lymphoma arises from a germinal center B-cell proliferation supported by a bidirectional crosstalk with tumor microenvironment, in particular with…”
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Integrative Analysis of Cell Crosstalk within Follicular Lymphoma Cell Niche: Towards a Definition of the FL Supportive Synapse
Published in Cancers (05-10-2020)“…Follicular lymphoma (FL), the most frequent indolent non-Hodgkin’s B cell lymphoma, is considered as a prototypical centrocyte-derived lymphoma, dependent on a…”
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BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization
Published in Autophagy (01-07-2014)“…We recently reported that BAG6/BAT3 (BCL2-associated athanogene 6) is essential for basal and starvation-induced autophagy in E18.5 bag6 −/− mouse embryos and…”
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Whole-genome expression analysis in primary human keratinocyte cell cultures exposed to 60 GHz radiation
Published in Bioelectromagnetics (01-02-2012)“…The main purpose of this study is to investigate potential responses of skin cells to millimeter wave (MMW) radiation increasingly used in the wireless…”
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Abstract 4810: Exome sequencing of refractory diffuse large B-cell lymphomas highlights candidate genes for targeted resequencing
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract As the most common lymphoid malignancy, Diffuse Large B-Cell Lymphoma (DLBCL) has largely benefited from immunochemotherapy combinations developed in…”
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Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and Non-L265P Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases
Published in Blood (02-12-2016)“…Introduction: MYD88 mutations, notably the recurrent gain-of-function L265P variant, are a distinguishing feature of Activated B-Cell like (ABC) Diffuse Large…”
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Sequential interplay between BAG6 and HSP70 upon heat shock
Published in Cellular and molecular life sciences : CMLS (01-06-2009)“… BAG6/Scythe/Bat3 is a cochaperone of the heat shock protein HSP70 and is involved in various developmental processes, cellular stress and viability. BAG6…”
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