Search Results - "Desmet, J."

Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination by Desmet, Christophe J., Ishii, Ken J.

“…Key Points To elicit protective adaptive immune responses, vaccines must efficiently trigger the innate immune system. It is becoming increasingly apparent…”
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Improving the utilization factor of a PEM electrolyzer powered by a 15 MW PV park by combining wind power and battery storage – Feasibility study by Papadopoulos, V., Desmet, J., Knockaert, J., Develder, C.

“…So far, the biggest photovoltaic park in Belgium has been injecting all its energy into the electric distribution grid through a power purchase agreement with…”
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Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia by Crotta, Stefania, Davidson, Sophia, Mahlakoiv, Tanel, Desmet, Christophe J, Buckwalter, Matthew R, Albert, Matthew L, Staeheli, Peter, Wack, Andreas

“…Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to…”
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Glucocorticoid receptors: finding the middle ground by Desmet, Sofie J, De Bosscher, Karolien

“…Glucocorticoids (GCs; referred to clinically as corticosteroids) are steroid hormones with potent anti-inflammatory and immune modulatory profiles. Depending…”
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DNA released from dying host cells mediates aluminum adjuvant activity by Marichal, Thomas, Ohata, Keiichi, Bedoret, Denis, Mesnil, Claire, Sabatel, Catherine, Kobiyama, Kouji, Lekeux, Pierre, Coban, Cevayir, Akira, Shizuo, Ishii, Ken J, Bureau, Fabrice, Desmet, Christophe J

“…How alum acts as a vaccine adjuvant continues to perplex. Here Marichal et al . now report that alum induces host cell death and release of genomic DNA, which…”
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Eosinophils as Drivers of Severe Eosinophilic Asthma: Endotypes or Plasticity? by Van Hulst, Glenn, Bureau, Fabrice, Desmet, Christophe J.

“…Asthma is now recognized as a heterogeneous disease, encompassing different phenotypes driven by distinct pathophysiological mechanisms called endotypes…”
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The interstitial macrophage: A long-neglected piece in the puzzle of lung immunity by Liegeois, Maude, Legrand, Celine, Desmet, Christophe J., Marichal, Thomas, Bureau, Fabrice

“…•Lung interstitial macrophages have long been ignored by scientists.•Lung interstitial macrophages are ontogenically distinct from alveolar macrophages.•Lung…”
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Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages by Sabatel, Catherine, Radermecker, Coraline, Fievez, Laurence, Paulissen, Genevieve, Chakarov, Svetoslav, Fernandes, Claudia, Olivier, Sabine, Toussaint, Marie, Pirottin, Dimitri, Xiao, Xue, Quatresooz, Pascale, Sirard, Jean-Claude, Cataldo, Didier, Gillet, Laurent, Bouabe, Hicham, Desmet, Christophe J., Ginhoux, Florent, Marichal, Thomas, Bureau, Fabrice

“…Living in a microbe-rich environment reduces the risk of developing asthma. Exposure of humans or mice to unmethylated CpG DNA (CpG) from bacteria reproduces…”
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Anti-IL5 mepolizumab minimally influences residual blood eosinophils in severe asthma by Van Hulst, Glenn, Jorssen, Joseph, Jacobs, Nathalie, Henket, Monique, Louis, Renaud, Schleich, Florence, Bureau, Fabrice, Desmet, Christophe J

“…Neutralising antibodies against the cytokine interleukin (IL)5 have become widely used for the control of severe eosinophilic asthma. Remarkably, patients…”
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Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer by Delaunay, Sylvain, Rapino, Francesca, Tharun, Lars, Zhou, Zhaoli, Heukamp, Lukas, Termathe, Martin, Shostak, Kateryna, Klevernic, Iva, Florin, Alexandra, Desmecht, Hadrien, Desmet, Christophe J, Nguyen, Laurent, Leidel, Sebastian A, Willis, Anne E, Büttner, Reinhard, Chariot, Alain, Close, Pierre

“…Quantitative and qualitative changes in mRNA translation occur in tumor cells and support cancer progression and metastasis. Posttranscriptional modifications…”
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Assessment of predictive factors for recurrence in laparoscopic ventral hernia repair using a bridging technique by Hauters, P., Desmet, J., Gherardi, D., Dewaele, S., Poilvache, H., Malvaux, P.

“…Aim To assess the long-term incidence and predictive factors for recurrence after laparoscopic ventral hernia repair using a bridging technique. Methods The…”
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Overvoltage and voltage unbalance mitigation in areas with high penetration of renewable energy resources by using the modified three-phase damping control strategy by Bozalakov, D.V., Laveyne, J., Desmet, J., Vandevelde, L.

“…•Solves overvoltage problems in low voltage distribution grids.•Mitigates the voltage unbalance in low voltage distribution grids.•Reduces the active power…”
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Investigating the need for real time measurements in industrial wind power systems combined with battery storage by Papadopoulos, V., Knockaert, J., Develder, C., Desmet, J.

“…•Simulating wind power systems at 10 min resolution results in remarkable errors.•The total self-sufficiency is overestimated with an error range of…”
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Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network by Kuilman, Thomas, Michaloglou, Chrysiis, Vredeveld, Liesbeth C.W., Douma, Sirith, van Doorn, Remco, Desmet, Christophe J., Aarden, Lucien A., Mooi, Wolter J., Peeper, Daniel S.

“…Oncogene-induced cellular senescence (OIS) is emerging as a potent cancer-protective response to oncogenic events, serving to eliminate early neoplastic cells…”
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Ten-year outcomes after primary vertical sleeve gastrectomy for morbid obesity: a monocentric cohort study by Hauters, P., Dubart, J.-W., Desmet, J., Degolla, R., Roumain, M., Malvaux, P.

“…Objective To assess the 10-year outcomes after sleeve gastrectomy (SG). Primary end-points were the long-term weight loss and the need for conversion and one…”
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Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor cell origin by Komuta, Mina, Spee, Bart, Borght, Sara Vander, De Vos, Rita, Verslype, Chris, Aerts, Raymond, Yano, Hirohisa, Suzuki, Tetsuya, Matsuda, Masanori, Fujii, Hideki, Desmet, Valeer J., Kojiro, Masamichi, Roskams, Tania

“…Cholangiolocellular carcinoma (CLC), a subtype of cholangiocellular carcinoma (CC), is thought to originate from the ductules/canals of Hering, where hepatic…”
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Editorial: The development and plasticity of myeloid immunity in the lung by Schetters, Sjoerd T T, Dammeijer, Floris, Desmet, Christophe J

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Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts by Desmet, K L J, Van Hoeck, V, Gagné, D, Fournier, E, Thakur, A, O'Doherty, A M, Walsh, C P, Sirard, M A, Bols, P E J, Leroy, J L M R

“…Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility…”
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Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate by Rapino, Francesca, Zhou, Zhaoli, Roncero Sanchez, Ana Maria, Joiret, Marc, Seca, Christian, El Hachem, Najla, Valenti, Gianluca, Latini, Sara, Shostak, Kateryna, Geris, Liesbet, Li, Ping, Huang, Gang, Mazzucchelli, Gabriel, Baiwir, Dominique, Desmet, Christophe J., Chariot, Alain, Georges, Michel, Close, Pierre

“…Regulation of mRNA translation elongation impacts nascent protein synthesis and integrity and plays a critical role in disease establishment. Here, we…”
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Ductal plates in hepatic ductular reactions. Hypothesis and implications. III. Implications for liver pathology by Desmet, Valeer J.

“…This article discusses on the basis of the ductal plate hypothesis the implication of the concept for several liver abnormalities. The occurrence of ductal…”
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