Search Results - "Desmazieres, Anne"

Myelin Plasticity and Repair: Neuro-Glial Choir Sets the Tuning by Ronzano, Remi, Thetiot, Melina, Lubetzki, Catherine, Desmazieres, Anne

“…The plasticity of the central nervous system (CNS) in response to neuronal activity has been suggested as early as 1894 by Cajal (1894). CNS plasticity has…”
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A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment by Zonta, Barbara, Desmazieres, Anne, Rinaldi, Arianna, Tait, Steven, Sherman, Diane L., Nolan, Matthew F., Brophy, Peter J.

“…The axon initial segment (AIS) is critical for the initiation and propagation of action potentials. Assembly of the AIS requires interactions between…”
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Rapid disruption of axon-glial integrity in response to mild cerebral hypoperfusion by Reimer, Michell M, McQueen, Jamie, Searcy, Luke, Scullion, Gillian, Zonta, Barbara, Desmazieres, Anne, Holland, Philip R, Smith, Jessica, Gliddon, Catherine, Wood, Emma R, Herzyk, Pawel, Brophy, Peter J, McCulloch, James, Horsburgh, Karen

“…Myelinated axons have a distinct protein architecture essential for action potential propagation, neuronal communication, and maintaining cognitive function…”
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Nodes of Ranvier during development and repair in the CNS by Lubetzki, Catherine, Sol-Foulon, Nathalie, Desmazières, Anne

“…Saltatory conduction of action potentials along myelinated axons depends on the nodes of Ranvier — small unmyelinated axonal domains where voltage-gated sodium…”
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Disruption of Krox20-Nab Interaction in the Mouse Leads to Peripheral Neuropathy with Biphasic Evolution by Desmazieres, Anne, Decker, Laurence, Vallat, Jean-Michel, Charnay, Patrick, Gilardi-Hebenstreit, Pascale

“…Krox20/Egr2 is a zinc finger transcription factor that plays essential roles in several developmental processes, including peripheral nervous system…”
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Mechanisms of sodium channel clustering and its influence on axonal impulse conduction by Freeman, Sean A, Desmazières, Anne, Fricker, Desdemona, Lubetzki, Catherine, Sol-Foulon, Nathalie

“…The efficient propagation of action potentials along nervous fibers is necessary for animals to interact with the environment with timeliness and precision…”
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Acceleration of conduction velocity linked to clustering of nodal components precedes myelination by Freeman, Sean A., Desmazières, Anne, Simonnet, Jean, Gatta, Marie, Pfeiffer, Friederike, Aigrot, Marie Stéphane, Rappeneau, Quentin, Guerreiro, Serge, Michel, Patrick Pierre, Yanagawa, Yuchio, Barbin, Gilles, Brophy, Peter J., Fricker, Desdemona, Lubetzki, Catherine, Sol-Foulon, Nathalie

“…Significance Cellular and molecular mechanisms underlying the assembly of nodes of Ranvier of myelinated axons in the CNS are still only partly understood. Our…”
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Progressive ataxia of Charolais cattle highlights a role of KIF1C in sustainable myelination by Duchesne, Amandine, Vaiman, Anne, Frah, Magali, Floriot, Sandrine, Legoueix-Rodriguez, Sabrina, Desmazières, Anne, Fritz, Sébastien, Beauvallet, Christian, Albaric, Olivier, Venot, Eric, Bertaud, Maud, Saintilan, Romain, Guatteo, Raphaël, Esquerré, Diane, Branchu, Julien, Fleming, Anaïs, Brice, Alexis, Darios, Frédéric, Vilotte, Jean-Luc, Stevanin, Giovanni, Boichard, Didier, El Hachimi, Khalid Hamid

“…Hereditary spastic paraplegias (HSPs) are clinically and genetically heterogeneous human neurodegenerative diseases. Amongst the identified genetic causes,…”
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Interaction between Neurons and the Oligodendroglial Lineage in Multiple Sclerosis and Its Preclinical Models by Pantazou, Vasiliki, Roux, Thomas, Oliveira Moreira, Vanessa, Lubetzki, Catherine, Desmazières, Anne

“…Multiple sclerosis (MS) is a complex central nervous system inflammatory disease leading to demyelination and associated functional deficits. Though endogenous…”
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Changes at the nodal and perinodal axonal domains: a basis for multiple sclerosis pathology? by Desmazières, Anne, Sol-Foulon, Nathalie, Lubetzki, Catherine

“…How axonal damage, a major prognostic factor of multiple sclerosis disability progression, is induced, is likely to be multifactorial. Whereas axonal injury…”
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Preparation and Immunostaining of Myelinating Organotypic Cerebellar Slice Cultures by Thetiot, Melina, Ronzano, Rémi, Aigrot, Marie-Stéphane, Lubetzki, Catherine, Desmazières, Anne

“…In the nervous system, myelin is a complex membrane structure generated by myelinating glial cells, which ensheathes axons and facilitates fast electrical…”
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Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier by Zhang, Ao, Desmazieres, Anne, Zonta, Barbara, Melrose, Shona, Campbell, Graham, Mahad, Don, Li, Qiushi, Sherman, Diane L, Reynolds, Richard, Brophy, Peter J

“…Rapid nerve conduction in myelinated nerves requires the clustering of voltage-gated sodium channels at nodes of Ranvier. The Neurofascin (Nfasc) gene has a…”
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Krox20 Controls the Transcription of Its Various Targets in the Developing Hindbrain According to Multiple Modes by Desmazières, Anne, Charnay, Patrick, Gilardi-Hebenstreit, Pascale

“…The zinc finger transcription factor Krox20 plays an essential role in the vertebrate hindbrain segmentation process. It positively or negatively controls a…”
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Differential stability of PNS and CNS nodal complexes when neuronal neurofascin is lost by Desmazieres, Anne, Zonta, Barbara, Zhang, Ao, Wu, Lai-Man N, Sherman, Diane L, Brophy, Peter J

“…Fast, saltatory conduction in myelinated nerves requires the clustering of voltage-gated sodium channels (Nav) at nodes of Ranvier in a nodal complex. The…”
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An alternative mechanism of early nodal clustering and myelination onset in GABAergic neurons of the central nervous system by Thetiot, Melina, Freeman, Sean A., Roux, Thomas, Dubessy, Anne‐Laure, Aigrot, Marie‐Stéphane, Rappeneau, Quentin, Lejeune, François‐Xavier, Tailleur, Julien, Sol‐Foulon, Nathalie, Lubetzki, Catherine, Desmazieres, Anne

“…In vertebrates, fast saltatory conduction along myelinated axons relies on the node of Ranvier. How nodes assemble on CNS neurons is not yet fully understood…”
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Live imaging of targeted cell ablation in Xenopus: a new model to study demyelination and repair by Kaya, Ferdinand, Mannioui, Abdelkrim, Chesneau, Albert, Sekizar, Sowmya, Maillard, Emmanuelle, Ballagny, Chantal, Houel-Renault, Ludivine, Dupasquier, David, Bronchain, Odile, Holtzmann, Isabelle, Desmazieres, Anne, Thomas, Jean-Léon, Demeneix, Barbara A, Brophy, Peter J, Zalc, Bernard, Mazabraud, Andre

“…Live imaging studies of the processes of demyelination and remyelination have so far been technically limited in mammals. We have thus generated a Xenopus…”
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Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction by Roche, Sarah L, Sherman, Diane L, Dissanayake, Kosala, Soucy, Geneviève, Desmazieres, Anne, Lamont, Douglas J, Peles, Elior, Julien, Jean-Pierre, Wishart, Thomas M, Ribchester, Richard R, Brophy, Peter J, Gillingwater, Thomas H

“…Postnatal synapse elimination plays a critical role in sculpting and refining neural connectivity throughout the central and peripheral nervous systems,…”
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Nodes of Ranvier during development and repair in the central nervous system by Lubetzki, Catherine, Sol-Foulon, Nathalie, Foulon, Nathalie Sol, Desmazières, Anne

“…Saltatory conduction of action potentials along myelinated axons depends on small unmyelinated axonal domains, the nodes of Ranvier, where voltage-gated sodium…”
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Role of a Contactin multi‐molecular complex secreted by oligodendrocytes in nodal protein clustering in the CNS by Dubessy, Anne‐Laure, Mazuir, Elisa, Rappeneau, Quentin, Ou, Sokounthie, Abi Ghanem, Charly, Piquand, Kevin, Aigrot, Marie‐Stéphane, Thétiot, Melina, Desmazières, Anne, Chan, Eric, Fitzgibbon, Matt, Fleming, Mark, Krauss, Raul, Zalc, Bernard, Ranscht, Barbara, Lubetzki, Catherine, Sol‐Foulon, Nathalie

“…The fast and reliable propagation of action potentials along myelinated fibers relies on the clustering of voltage‐gated sodium channels at nodes of Ranvier…”
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Krox20 Controls the Transcription of Its Various Targets in the Developing Hindbrain According to Multiple ModesS by Desmazières, Anne, Charnay, Patrick, Gilardi-Hebenstreit, Pascale

“…The zinc finger transcription factor Krox20 plays an essential role in the vertebrate hindbrain segmentation process. It positively or negatively controls a…”
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