Search Results - "Deshpande, Sumukh"
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Effect of Adiantum philippense Extract on Biofilm Formation, Adhesion With Its Antibacterial Activities Against Foodborne Pathogens, and Characterization of Bioactive Metabolites: An in vitro-in silico Approach
Published in Frontiers in microbiology (13-05-2020)“…Adiantum philippense ( A. philippense ), an ethnomedicinally important fern, has become an interesting herb in the search for novel bioactive metabolites,…”
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Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Published in RSC advances (13-10-2020)“…The outbreak of novel coronavirus, SARS-CoV-2, has infected more than 36 million people and caused approximately 1 million deaths around the globe as of 9…”
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Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation
Published in Nature communications (10-01-2022)“…Oxylipins are potent biological mediators requiring strict control, but how they are removed en masse during infection and inflammation is unknown. Here we…”
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Thymus musilii Velen. as a promising source of potent bioactive compounds with its pharmacological properties: In vitro and in silico analysis
Published in Arabian journal of chemistry (01-08-2020)“…For the first time, we reported the phytochemical composition of the volatile oil from Thymus musilii Velen (T. musilii). The antioxidant and antimicrobial…”
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Sex-specific proximal tubular cell differentiation pathways identified by single-nucleus RNA sequencing
Published in Scientific reports (14-10-2024)“…Postnatal kidney growth is substantial and involves expansion in kidney tubules without growth of new nephrons, which are the functional units of the kidney…”
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Modeling of Open, Closed, and Open-Inactivated States of the hERG1 Channel: Structural Mechanisms of the State-Dependent Drug Binding
Published in Journal of chemical information and modeling (22-10-2012)“…The human ether-a-go-go related gene 1 (hERG1) K ion channel is a key element for the rapid component of the delayed rectified potassium current in cardiac…”
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Bioactivities and in silico study of Pergularia tomentosa L. phytochemicals as potent antimicrobial agents targeting type IIA topoisomerase, TyrRS, and Sap1 virulence proteins
Published in Environmental science and pollution research international (01-05-2021)“…Pergularia tomentosa L. ( P. tomentosa ) has been largely used in Tunisian folk medicine as remedies against skin diseases, asthma, and bronchitis. The main…”
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A high ratio of linoleic acid (n-6 PUFA) to alpha-linolenic acid (n-3 PUFA) adversely affects early stage of human neuronal differentiation and electrophysiological activity of glutamatergic neurons in vitro
Published in Frontiers in cell and developmental biology (15-05-2023)“…There is a growing interest in the possibility of dietary supplementation with polyunsaturated fatty acids (PUFAs) for treatment and prevention of…”
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PLIT: An alignment-free computational tool for identification of long non-coding RNAs in plant transcriptomic datasets
Published in Computers in biology and medicine (01-02-2019)“…Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome…”
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Single-Nucleus RNA Sequencing Identifies Sex-Specific Proximal Tubular Cell Differentiation Pathways: FR-PO365
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia
Published in Leukemia (01-02-2023)“…Nuclear factor I-C (NFIC) belongs to a family of NFI transcription factors that binds to DNA through CAATT-boxes and are involved in cellular differentiation…”
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