Search Results - "Deshpande, Shailesh S."

Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion‐induced necrosis and apoptosis in vivo by Ozaki, Michitaka, S. Deshpande, Shailesh, Angkeow, Piamsook, Bellan, John, J. Lowenstein, Charles, C. Dinauer, Mary, J. Goldschmidt-Clermont, Pascal, Irani, Kaikobad

“…ABSTRACT Reperfusion of ischemic tissue results in the generation of reactive oxygen species that contribute to tissue injury. The sources of reactive oxygen…”
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Shear-induced tyrosine phosphorylation in endothelial cells requires Rac1-dependent production of ROS by Yeh, L H, Park, Y J, Hansalia, R J, Ahmed, I S, Deshpande, S S, Goldschmidt-Clermont, P J, Irani, K, Alevriadou, B R

“…The shear-induced intracellular signal transduction pathway in vascular endothelial cells involves tyrosine phosphorylation and activation of mitogen-activated…”
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Mechanism(s) of turmeric-mediated protective effects against benzo(a)pyrene-derived DNA adducts by Thapliyal, Rachana, Deshpande, Shailesh S, Maru, Girish B

“…The effects of turmeric feeding before and after benzo(a)pyrene [B(a)P] exposure on the levels of B(a)P-derived DNA adducts were studied in tissues of Swiss…”
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Spectral Overlap Correction Using Weighted Deconvolution for Improved Dark Object Technique for Correction of EO1-Hyperion Data by Deshpande, Shailesh S., Inamdar, Arun B., Buddhiraju, Krishna Mohan

“…We present a critical modification to improved dark object technique for correcting hyperspectral data (EO1-Hyperion). The modification is required in improved…”
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Chemopreventive efficacy of curcumin-free aqueous turmeric extract in 7,12-dimethylbenz[ a]anthracene-induced rat mammary tumorigenesis by Deshpande, Shailesh S, Ingle, Arvind D, Maru, Girish B

“…The modulating effects of turmeric (T), ethanolic turmeric extract (ETE) and curcumin-free aqueous turmeric extract (CFATE) on the initiation or…”
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Effects of turmeric on the activities of benzo(a)pyrene-induced cytochrome P-450 isozymes by Thapliyal, R, Deshpande, S S, Maru, G B

“…Turmeric and/or its main coloring component, curcumin (diferuloylmethane), have been shown to inhibit benzo(a)pyrene [B(a)P]-induced forestomach papillomas in…”
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Semi-Supervised Learning by Domain Adaptation for Hyperspectral Image Classification by Deshpande, Shailesh S., Banolia, Chaman, Balamuralidhar, P.

“…Classification of remotely sensed data is the mainstay of analysis methods for generating actionable insights. Classification of remotely sensed data is…”
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Estimation of Carbon Fluxes from a City at 1 km × 1 km Grid Using Remotely Sensed Data by Banolia, Chaman, Deshpande, Shailesh S., Balamuralidhar, P.

“…In today's world, environmental pollution is worsening and having detrimental effects on the environment. The current focus of human endeavors is aimed at…”
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Approximate and Quick Estimation of Carbon Emissions from a City Using Remotely Sensed Data by Deshpande, Shailesh S., Banolia, Chaman, P., Balamuralidhar

“…Calculating CO 2 emissions from a city using Global Protocol for Communities (GPC) guidelines is a data intensive exercise. Moreover, the outcome is difficult…”
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Rac1 Regulates Stress-induced, Redox-dependent Heat Shock Factor Activation by Ozaki, Michitaka, Deshpande, Shailesh S., Angkeow, Piamsook, Suzuki, Seiichi, Irani, Kaikobad

“…The signaling pathway by which environmental stresses activate heat shock factors (HSFs) is not completely understood. We show that the small GTPase rac1, and…”
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Constitutive activation of rac1 results in mitochondrial oxidative stress and induces premature endothelial cell senescence by DESHPANDE, Shailesh S, BING QI, YOUNG CHUL PARK, IRANI, Kaikobad

“…Oxidative stress has been implicated in cellular senescence and vascular aging. We determined the role and mechanism of the small GTPase rac1 in vascular…”
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Adhesion of flowing monocytes to hypoxia-reoxygenation-exposed endothelial cells: role of Rac1, ROS, and VCAM-1 by Ng, C K Domingos, Deshpande, Shailesh S, Irani, Kaikobad, Alevriadou, B Rita

“…Production of reactive oxygen species (ROS) by ischemic tissue after ischemia-reperfusion (I/RP) is an important factor that contributes to tissue injury. The…”
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Constitutive Activation of rac 1 Results in Mitochondrial Oxidative Stress and Induces Premature Endothelial Cell Senescence by Deshpande, Shailesh S, Qi, Bing, Park, Young Chul, Irani, Kaikobad

“…OBJECTIVE—Oxidative stress has been implicated in cellular senescence and vascular aging. We determined the role and mechanism of the small GTPase rac1 in…”
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Inhibitory effects of curcumin-free aqueous turmeric extract on benzo[ a]pyrene-induced forestomach papillomas in mice by Deshpande, Shailesh S., Ingle, Arvind D., Maru, G.B.

“…The modulating effects of curcumin-free aqueous turmeric extract (CFATE), ethanolic turmeric extract (ETE) and turmeric (T) powder on the benzo( a)pyrene (B(…”
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Rac1 regulates the release of Weibel-Palade Bodies in human aortic endothelial cells by Yang, Shui-xiang, Yan, Juan, Deshpande, Shailesh S, Irani, Kaikobad, Lowenstein, Charles J

“…The release of Weibel-Palade Bodies (WPB) is a form of endothelial cell activation. But the signal transduction pathway leading to WPB release is not yet…”
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Expression of Id1 Results in Apoptosis of Cardiac Myocytes through a Redox-dependent Mechanism by Tanaka, Koichi, Pracyk, John B., Takeda, Kazuyo, Yu, Zu-Xi, Ferrans, Victor J., Deshpande, Shailesh S., Ozaki, Michitaka, Hwang, Paul M., Lowenstein, Charles J., Irani, Kaikobad, Finkel, Toren

“…We have constructed a recombinant adenovirus (Ad.Id1) that allows for efficient expression of the helix-loop-helix protein Id1. After infection with Ad.Id1,…”
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Effects of curcumin on the formation of benzo[ a]pyrene derived DNA adducts in vitro by Deshpande, Shailesh S., Maru, Girish B.

“…The effects of turmeric (T), curcumins (Cs), aqueous turmeric extract (ATE) and curcumin-free aqueous turmeric extract (CFATE) on the formation of [ 3H]benzo[…”
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Vascular endothelial growth factor induces manganese‐superoxide dismutase expression in endothelial cells by a Racl‐regulated NADPH oxidase‐dependent mechanism by Abid, Md. Ruhul, Tsai, Jo C., Spokes, Katherine C., Deshpande, Shailesh S., Irani, Kaikobad, Aird, William C.

“…ABSTRACT Vascular endothelial growth factor (VEGF) is a potent vascular endothelial cell‐specific mitogen that modulates endothelial cell function. In the…”
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Domain Aware Learning for Hyperspectral Image Classification using Spectral-Spatial Features from Externally Labelled Data by Aswal, Shreyansh, Banolia, Chaman, Deshpande, Shailesh S.

“…One of the major challenges in the classification of remotely sensed hyperspectral data is the limited number of labelled pixels within an image. This means…”
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Rac1 inhibits TNF‐α‐induced endothelial cell apoptosis: dual regulation by reactive oxygen species by Deshpande, Shailesh S., Angkeow, Piamsook, Huang, Jianping, Ozaki, Michitaka, Irani, Kaikobad

“…Reactive oxygen species (ROS) have been implicated as mediators of tumor necrosis factor‐alpha (TNF) ‐induced apoptosis. In addition to leading to cell death,…”
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