Noncoding RNA

Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as , control the expression of genes encoding virulence factors or metabolic proteins. They are extremely diverse and include noncoding RNAs (sRNA), antisense RNAs, and some 5' or 3' untranslate...

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Bibliographic Details
Published in:	Microbiology spectrum Vol. 7; no. 2
Main Authors:	Desgranges, E, Marzi, S, Moreau, K, Romby, P, Caldelari, I
Format:	Journal Article
Language:	English
Published:	United States ASM Press 01-03-2019 American Society for Microbiology
Subjects:	Bacterial Genetics, Cell Biology, Physiology Biochemistry, Molecular Biology Life Sciences Molecular biology RNA, Bacterial RNA, Small Untranslated Staphylococcus aureus
Online Access:	Get full text
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Summary:	Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as , control the expression of genes encoding virulence factors or metabolic proteins. They are extremely diverse and include noncoding RNAs (sRNA), antisense RNAs, and some 5' or 3' untranslated regions of messenger RNAs that act as sensors for metabolites, tRNAs, or environmental conditions (e.g., temperature, pH). In this review we focus on specific examples of sRNAs of that illustrate how numerous sRNAs and associated proteins are embedded in complex networks of regulation. In addition, we discuss the CRISPR-Cas systems defined as an RNA-interference-like mechanism, which also exist in staphylococcal strains.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	2165-0497 2165-0497
DOI:	10.1128/microbiolspec.GPP3-0038-2018