Search Results - "Deschénes, J"
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Comb-calibrated laser ranging for three-dimensional surface profiling with micrometer-level precision at a distance
Published in Optics express (20-10-2014)“…Non-contact surface mapping at a distance is interesting in diverse applications including industrial metrology, manufacturing, forensics, and artifact…”
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Palmitoylation: policing protein stability and traffic
Published in Nature reviews. Molecular cell biology (01-01-2007)“…Palmitate modifies both peripheral and integral membrane proteins and its addition can be permanent or transient, which makes it unique among the lipid…”
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An Extremum Seeking Strategy Based on Block-Oriented Models: Application to Biomass Productivity Maximization in Microalgae Cultures
Published in Industrial & engineering chemistry research (31-07-2019)“…This paper proposes an adaptive slope seeking strategy targeting any reachable operating pointincluding extremumon the input/output map of a general dynamic…”
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DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors
Published in Molecular biology of the cell (01-01-2012)“…Classical estrogen, progesterone, and androgen receptors (ERs, PRs, and ARs) localize outside the nucleus at the plasma membrane of target cells. From the…”
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5
Middle Mesial Canals in Mandibular Molars: Incidence and Related Factors
Published in Journal of endodontics (01-01-2015)“…Abstract Introduction Although the internal anatomy of mandibular molars has been extensively studied, information about middle mesial (MM) canals is limited…”
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Low-dose inhaled and nasal corticosteroid use and the risk of cataracts
Published in The European respiratory journal (01-06-2006)“…Orally inhaled corticosteroid use has been convincingly linked to an increase in the risk of cataracts, although the risk at lower doses in common use remains…”
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Mutational Analysis of Saccharomyces cerevisiae Erf2 Reveals a Two-step Reaction Mechanism for Protein Palmitoylation by DHHC Enzymes
Published in The Journal of biological chemistry (03-12-2010)“…DHHC protein acyltransferases (PATs) catalyze the palmitoylation of eukaryotic proteins through an enzymatic mechanism that remains largely unexplored. In this…”
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Hybrid photobioreactor operation for the intensified production of Haslea ostrearia and marennine in function of strain variability
Published in Algal research (Amsterdam) (01-09-2023)“…Marennine is a high-value compound produced by the benthic diatom Haslea ostrearia, which could be used as an alternative to synthetic antibiotics in…”
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Identification of a Ras Palmitoyltransferase in Saccharomyces cerevisiae
Published in The Journal of biological chemistry (25-10-2002)“…Most Ras proteins are posttranslationally modified by a palmitoyl lipid moiety through a thioester linkage. However, the mechanism by which this occurs is not…”
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Identification of SARS-CoV-2 Spike Palmitoylation Inhibitors That Results in Release of Attenuated Virus with Reduced Infectivity
Published in Viruses (04-03-2022)“…The spike proteins of enveloped viruses are transmembrane glycoproteins that typically undergo post-translational attachment of palmitate on cysteine residues…”
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DHHC9 and GCP16 Constitute a Human Protein Fatty Acyltransferase with Specificity for H- and N-Ras
Published in The Journal of biological chemistry (02-09-2005)“…Covalent lipid modifications mediate the membrane attachment and biological activity of Ras proteins. All Ras isoforms are farnesylated and carboxyl-methylated…”
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Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome
Published in Nature communications (22-09-2016)“…Endothelial dysfunction is a hallmark of systemic inflammatory response underlying multiple organ failure. Here we report a novel function of DHHC-containing…”
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Mutations in the X-linked Intellectual Disability Gene, zDHHC9, Alter Autopalmitoylation Activity by Distinct Mechanisms
Published in The Journal of biological chemistry (27-06-2014)“…Early onset intellectual disabilities result in significant societal and economic costs and affect 1–3% of the population. The underlying genetic determinants…”
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Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library
Published in Combinatorial chemistry & high throughput screening (01-05-2016)“…The addition of palmitoyl moieties to proteins regulates their membrane targeting, subcellular localization, and stability. Dysregulation of the enzymes which…”
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Posttransplant Lymphoproliferative Disorder After Clinical Islet Transplantation: Report of the First Two Cases
Published in American journal of transplantation (01-09-2017)“…We report the first two cases of posttransplant lymphoproliferative disorder (PTLD) in recipients of islet transplants worldwide. First, a 44‐year‐old…”
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Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells
Published in Nucleic acids research (01-01-2008)“…Estrogen receptors (ERs), which mediate the proliferative action of estrogens in breast cancer cells, are ligand-dependent transcription factors that regulate…”
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Plasma Membrane Localization of Ras Requires Class C Vps Proteins and Functional Mitochondria in Saccharomyces cerevisiae
Published in Molecular and Cellular Biology (01-04-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Model organisms lead the way to protein palmitoyltransferases
Published in Journal of cell science (01-02-2004)“…The acylation of proteins with palmitate and related fatty acids has been known for over 30 years, but the molecular machinery that carries out palmitoylation…”
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International Uveitis Study Group (IUSG) Clinical Classification of Uveitis
Published in Ocular immunology and inflammation (2008)“…A simplified clinical classification system of uveitis has been proposed by the International Uveitis Study Group. Its aim is to assist in the diagnosis and…”
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New Insights into the Mechanisms of Protein Palmitoylation
Published in Biochemistry (Easton) (22-04-2003)“…Since its discovery more than 30 years ago, protein palmitoylation has been shown to have a role in protein−membrane interactions, protein trafficking, and…”
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