Search Results - "Desch, A. Nicole"

Transcriptome analysis highlights the conserved difference between embryonic and postnatal-derived alveolar macrophages by Gibbings, Sophie L., Goyal, Rajni, Desch, A. Nicole, Leach, Sonia M., Prabagar, Miglena, Atif, Shaikh M., Bratton, Donna L., Janssen, William, Jakubzick, Claudia V.

“…Alveolar macrophages (AMs) reside on the luminal surfaces of the airways and alveoli where they maintain host defense and promote alveolar homeostasis by…”
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C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions by Mohanan, Vishnu, Nakata, Toru, Desch, A Nicole, Lévesque, Chloé, Boroughs, Angela, Guzman, Gaelen, Cao, Zhifang, Creasey, Elizabeth, Yao, Junmei, Boucher, Gabrielle, Charron, Guy, Bhan, Atul K, Schenone, Monica, Carr, Steven A, Reinecker, Hans-Christian, Daly, Mark J, Rioux, John D, Lassen, Kara G, Xavier, Ramnik J

“…Polymorphisms in are associated with increased risk of inflammatory bowel disease (IBD). However, the function of C1orf106 and the consequences of…”
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Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes by Desch, A Nicole, Gibbings, Sophie L, Goyal, Rajni, Kolde, Raivo, Bednarek, Joe, Bruno, Tullia, Slansky, Jill E, Jacobelli, Jordan, Mason, Robert, Ito, Yoko, Messier, Elise, Randolph, Gwendalyn J, Prabagar, Miglena, Atif, Shaikh M, Segura, Elodie, Xavier, Ramnik J, Bratton, Donna L, Janssen, William J, Henson, Peter M, Jakubzick, Claudia V

“…The pulmonary mononuclear phagocyte system is a critical host defense mechanism composed of macrophages, monocytes, monocyte-derived cells, and dendritic…”
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CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen by Desch, A Nicole, Randolph, Gwendalyn J, Murphy, Kenneth, Gautier, Emmanuel L, Kedl, Ross M, Lahoud, Mireille H, Caminschi, Irina, Shortman, Ken, Henson, Peter M, Jakubzick, Claudia V

“…Cells undergoing programmed cell death (apoptosis) are removed in situ by macrophages and dendritic cells (DCs) through a specialized form of phagocytosis…”
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MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer by Zarling, Angela L, Obeng, Rebecca C, Desch, A Nicole, Pinczewski, Joel, Cummings, Kara L, Deacon, Donna H, Conaway, Mark, Slingluff, Jr, Craig L, Engelhard, Victor H

“…Cancer cells display novel phosphopeptides in association with MHC class I and II molecules. In this study, we evaluated two HLA-A2-restricted phosphopeptides…”
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TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation by Graham, Daniel B., Lefkovith, Ariel, Deelen, Patrick, de Klein, Niek, Varma, Mukund, Boroughs, Angela, Desch, A. Nicole, Ng, Aylwin C.Y., Guzman, Gaelen, Schenone, Monica, Petersen, Christine P., Bhan, Atul K., Rivas, Manuel A., Daly, Mark J., Carr, Steven A., Wijmenga, Cisca, Xavier, Ramnik J.

“…Significant insights into disease pathogenesis have been gleaned from population-level genetic studies; however, many loci associated with complex genetic…”
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Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts by Atif, Shaikh M, Nelsen, Michelle K, Gibbings, Sophie L, Desch, A Nicole, Kedl, Ross M, Gill, Ronald G, Marrack, Philippa, Murphy, Kenneth M, Grazia, Todd J, Henson, Peter M, Jakubzick, Claudia V

“…In transplantation, a major obstacle for graft acceptance in MHC-matched individuals is the mismatch of minor histocompatibility Ags. Minor histocompatibility…”
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Three Unique Interstitial Macrophages in the Murine Lung at Steady State by Gibbings, Sophie L, Thomas, Stacey M, Atif, Shaikh M, McCubbrey, Alexandra L, Desch, A Nicole, Danhorn, Thomas, Leach, Sonia M, Bratton, Donna L, Henson, Peter M, Janssen, William J, Jakubzick, Claudia V

“…The current paradigm in macrophage biology is that some tissues mainly contain macrophages from embryonic origin, such as microglia in the brain, whereas other…”
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Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction by Desch, A Nicole, Gibbings, Sophie L., Clambey, Eric T., Janssen, William J., Slansky, Jill E., Kedl, Ross M., Henson, Peter M., Jakubzick, Claudia

“…Dendritic cells (DCs) are required for the induction of cytotoxic T cells (CTL). In most tissues, including the lung, the resident DCs fall into two types…”
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Pulmonary dendritic cell development and antigen acquisition by Desch, A. Nicole, Henson, Peter M., Jakubzick, Claudia V.

“…Pulmonary dendritic cells (DCs) constantly sample the tissue and traffic inhaled antigens to the lung-draining lymph node where they normally orchestrate an…”
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Pulmonary dendritic cell development and antigen acquisition by Desch, A. Nicole, Henson, Peter M., Jakubzick, Claudia V.

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Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis by Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D’Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J.

“…Nature Communications 7 Article number: 12342 (2016); Published 9 August 2016; Updated 13 September 2016 The HTML version of this Article incorrectly listed…”
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Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis by Smillie, Christopher S., Biton, Moshe, Ordovas-Montanes, Jose, Sullivan, Keri M., Burgin, Grace, Graham, Daniel B., Herbst, Rebecca H., Rogel, Noga, Slyper, Michal, Waldman, Julia, Sud, Malika, Andrews, Elizabeth, Velonias, Gabriella, Haber, Adam L., Jagadeesh, Karthik, Vickovic, Sanja, Yao, Junmei, Stevens, Christine, Dionne, Danielle, Nguyen, Lan T., Villani, Alexandra-Chloé, Hofree, Matan, Creasey, Elizabeth A., Huang, Hailiang, Rozenblatt-Rosen, Orit, Garber, John J., Khalili, Hamed, Desch, A. Nicole, Daly, Mark J., Ananthakrishnan, Ashwin N., Shalek, Alex K., Xavier, Ramnik J., Regev, Aviv

“…Genome-wide association studies (GWAS) have revealed risk alleles for ulcerative colitis (UC). To understand their cell type specificities and pathways of…”
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A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis by Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D’Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H, Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J.

“…Protein-truncating variants protective against human disease provide in vivo validation of therapeutic targets. Here we used targeted sequencing to conduct a…”
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Cellular and inter-cellular rewiring of the human colon during ulcerative colitis by Smillie, Christopher S., Biton, Moshe, Ordovas-Montañes, José, Sullivan, Keri M., Burgin, Grace, Graham, Daniel B., Herbst, Rebecca H., Rogel, Noga, Slyper, Michal, Waldman, Julia, Sud, Malika, Andrews, Elizabeth, Velonias, Gabriella, Haber, Adam L., Jagadeesh, Karthik, Vickovic, Sanja, Yao, Junmei, Stevens, Christine, Dionne, Danielle, Nguyen, Lan T., Villani, Alexandra-Chloé, Hofree, Matan, Creasey, Elizabeth A., Huang, Hailiang, Rozenblatt-Rosen, Orit, Garber, John J., Khalili, Hamed, Desch, A. Nicole, Daly, Mark J., Ananthakrishnan, Ashwin N., Shalek, Alex K., Xavier, Ramnik J., Regev, Aviv

“…Genome-wide association studies (GWAS) have revealed risk alleles for ulcerative colitis (UC). To understand their cell type specificities and pathways of…”
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Three unique interstitial macrophages in the murine lung at steady state by Gibbings, Sophie L., Thomas, Stacey M., Frasch, Courtney S., Atif, Shaikh M., McCubbrey, Alexandra L., Desch, A. Nicole, Danhorn, Thomas, Leach, Sonia M, Bratton, Donna L., Henson, Peter M., Janssen, William J., Jakubzick, Claudia V.

“…Abstract Rationale The current paradigm in macrophage biology is that some tissues mainly contain macrophages from embryonic origin such as microglia in the…”
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Pulmonary dendritic cells require cis-activation to cross-prime T cells (APP4P.117) by Jakubzick, Claudia, Desch, A. Nicole, Gibbings, Sophie, Clambey, Eric, Janssen, William, Slanskey, Jill, Kedl, Ross, Henson, Peter

“…Abstract Dendritic cells (DCs) are required for the induction of cytotoxic T cells (CTL). In most tissues, including the lung, the resident migratory DC fall…”
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MHC-restricted phosphopeptides derived from Insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer by Zarling, Angela L., Obeng, Rebecca C., Desch, A. Nicole, Pinczewski, Joel, Cummings, Kara L., Deacon, Donna H., Conaway, Mark, Slingluff, Craig L., Engelhard, Victor H.

“…Cancer cells display novel phosphopeptides in association with MHC class I and II molecules. In this study, we evaluated two HLA-A2-restricted phosphopeptides…”
Get full text