Search Results - "Desai, Rishi J."

Alternative approaches for confounding adjustment in observational studies using weighting based on the propensity score: a primer for practitioners by Desai, Rishi J, Franklin, Jessica M

“…This report aims to provide methodological guidance to help practitioners select the most appropriate weighting method based on propensity scores for their…”
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Network-based approach to prediction and population-based validation of in silico drug repurposing by Cheng, Feixiong, Desai, Rishi J., Handy, Diane E., Wang, Ruisheng, Schneeweiss, Sebastian, Barabási, Albert-László, Loscalzo, Joseph

“…Here we identify hundreds of new drug-disease associations for over 900 FDA-approved drugs by quantifying the network proximity of disease genes and drug…”
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Comparative Risk of Venous Thromboembolism in Rheumatoid Arthritis Patients Receiving Tofacitinib Versus Those Receiving Tumor Necrosis Factor Inhibitors: An Observational Cohort Study by Desai, Rishi J., Pawar, Ajinkya, Weinblatt, Michael E., Kim, Seoyoung C.

“…Objective To evaluate the risk of venous thromboembolism (VTE) in rheumatoid arthritis (RA) patients receiving tofacitinib versus those receiving tumor…”
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Lithium Use in Pregnancy and the Risk of Cardiac Malformations by Patorno, Elisabetta, Huybrechts, Krista F, Bateman, Brian T, Cohen, Jacqueline M, Desai, Rishi J, Mogun, Helen, Cohen, Lee S, Hernandez-Diaz, Sonia

“…Whereas some prior data had suggested a large increase in the risk of cardiac malformations among offspring of women using lithium in early pregnancy, this…”
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Increase in Prescription Opioid Use During Pregnancy Among Medicaid-Enrolled Women by Desai, Rishi J., Hernandez-Diaz, Sonia, Bateman, Brian T., Huybrechts, Krista F.

“…To report the prevalence of prescription opioid use and evaluate the trends in a large cohort of Medicaid-enrolled pregnant women. A cohort of pregnancies was…”
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Antidepressant Use Late in Pregnancy and Risk of Persistent Pulmonary Hypertension of the Newborn by Huybrechts, Krista F, Bateman, Brian T, Palmsten, Kristin, Desai, Rishi J, Patorno, Elisabetta, Gopalakrishnan, Chandrasekar, Levin, Raisa, Mogun, Helen, Hernandez-Diaz, Sonia

“…IMPORTANCE: The association between selective serotonin reuptake inhibitor (SSRI) antidepressant use during pregnancy and risk of persistent pulmonary…”
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Antipsychotic Use in Pregnancy and the Risk for Congenital Malformations by Huybrechts, Krista F, Hernández-Díaz, Sonia, Patorno, Elisabetta, Desai, Rishi J, Mogun, Helen, Dejene, Sara Z, Cohen, Jacqueline M, Panchaud, Alice, Cohen, Lee, Bateman, Brian T

“…The frequency of antipsychotic (AP) use during pregnancy has approximately doubled during the last decade. However, little is known about their safety for the…”
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Risk of neonatal drug withdrawal after intrauterine co-exposure to opioids and psychotropic medications: cohort study by Huybrechts, Krista F, Bateman, Brian T, Desai, Rishi J, Hernandez-Diaz, Sonia, Rough, Kathryn, Mogun, Helen, Kerzner, Leslie S, Davis, Jonathan M, Stover, Megan, Bartels, Devan, Cottral, Jennifer, Patorno, Elisabetta

“…Objectives To assess the impact of in utero co-exposure to psychotropic medications and opioids on the incidence and severity of neonatal drug…”
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External validation of a claims-based model to predict left ventricular ejection fraction class in patients with heart failure by Mahesri, Mufaddal, Chin, Kristyn, Kumar, Abheenava, Barve, Aditya, Studer, Rachel, Lahoz, Raquel, Desai, Rishi J

“…Background Ejection fraction (EF) is an important prognostic factor in heart failure (HF), but administrative claims databases lack information on EF. We…”
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Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes by Park, Yoonyoung, Hernandez-Diaz, Sonia, Bateman, Brian T, Cohen, Jacqueline M, Desai, Rishi J, Patorno, Elisabetta, Glynn, Robert J, Cohen, Lee S, Mogun, Helen, Huybrechts, Krista F

“…Objective:Some atypical antipsychotics are associated with metabolic side effects, which are risk factors for gestational diabetes. The authors examined the…”
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Hydroxychloroquine lowers Alzheimer’s disease and related dementias risk and rescues molecular phenotypes related to Alzheimer’s disease by Varma, Vijay R., Desai, Rishi J., Navakkode, Sheeja, Wong, Lik-Wei, Anerillas, Carlos, Loeffler, Tina, Schilcher, Irene, Mahesri, Mufaddal, Chin, Kristyn, Horton, Daniel B., Kim, Seoyoung C., Gerhard, Tobias, Segal, Jodi B., Schneeweiss, Sebastian, Gorospe, Myriam, Sajikumar, Sreedharan, Thambisetty, Madhav

“…We recently nominated cytokine signaling through the Janus-kinase–signal transducer and activator of transcription (JAK/STAT) pathway as a potential AD drug…”
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Factors associated with initial or subsequent choice of biologic disease-modifying antirheumatic drugs for treatment of rheumatoid arthritis by Jin, Yinzhu, Desai, Rishi J, Liu, Jun, Choi, Nam-Kyong, Kim, Seoyoung C

“…Biologic disease-modifying antirheumatic drugs (DMARDs) are increasingly used for rheumatoid arthritis (RA) treatment. However, little is known based on…”
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Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset by Patorno, Elisabetta, Hernandez-Diaz, Sonia, Huybrechts, Krista F., Desai, Rishi J., Cohen, Jacqueline M., Mogun, Helen, Bateman, Brian T.

“…BACKGROUNDDespite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association…”
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Comparative effectiveness of generic and brand-name medication use: A database study of US health insurance claims by Desai, Rishi J, Sarpatwari, Ameet, Dejene, Sara, Khan, Nazleen F, Lii, Joyce, Rogers, James R, Dutcher, Sarah K, Raofi, Saeid, Bohn, Justin, Connolly, John G, Fischer, Michael A, Kesselheim, Aaron S, Gagne, Joshua J

“…To the extent that outcomes are mediated through negative perceptions of generics (the nocebo effect), observational studies comparing brand-name and generic…”
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An evaluation of longitudinal changes in serum uric acid levels and associated risk of cardio-metabolic events and renal function decline in gout by Desai, Rishi J, Franklin, Jessica M, Spoendlin-Allen, Julia, Solomon, Daniel H, Danaei, Goodarz, Kim, Seoyoung C

“…Gout patients have a high burden of co-morbid conditions including diabetes mellitus (DM), chronic kidney disease (CKD), and cardiovascular disease (CVD). We…”
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Comparative Cardiovascular Risk of Abatacept and Tumor Necrosis Factor Inhibitors in Patients With Rheumatoid Arthritis With and Without Diabetes Mellitus: A Multidatabase Cohort Study by Kang, Eun Ha, Jin, Yinzhu, Brill, Gregory, Lewey, Jennifer, Patorno, Elisabetta, Desai, Rishi J., Kim, Seoyoung C.

“…Background We examined the cardiovascular risk of abatacept compared with tumor necrosis factor (TNF) inhibitors in patients with rheumatoid arthritis with and…”
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Risk of Serious Infection Among Initiators of Tumor Necrosis Factor Inhibitors Plus Methotrexate Versus Triple Therapy for Rheumatoid Arthritis: A Cohort Study by Kang, Eun Ha, Jin, Yinzhu, Tong, Angela Y., Desai, Rishi J., Kim, Seoyoung C.

“…Objective To compare the risk of serious infections between the use of tumor necrosis factor inhibitors (TNFi) plus methotrexate (MTX) versus triple therapy…”
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Prospective validation of a dynamic prognostic model for identifying COVID‐19 patients at high risk of rapid deterioration by Lin, Kueiyu Joshua, D'Andrea, Elvira, Desai, Rishi J., Gagne, Joshua J., Liu, Jun, Wang, Shirley V.

“…Background We sought to develop and prospectively validate a dynamic model that incorporates changes in biomarkers to predict rapid clinical deterioration in…”
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Initiation Patterns of Disease-Modifying Antirheumatic Drugs That Have Potential to Exacerbate Heart Failure by Lee, Su Been, D'Andrea, Elvira, Desai, Rishi J

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Scalable incident detection via natural language processing and probabilistic language models by Walsh, Colin G., Wilimitis, Drew, Chen, Qingxia, Wright, Aileen, Kolli, Jhansi, Robinson, Katelyn, Ripperger, Michael A., Johnson, Kevin B., Carrell, David, Desai, Rishi J., Mosholder, Andrew, Dharmarajan, Sai, Adimadhyam, Sruthi, Fabbri, Daniel, Stojanovic, Danijela, Matheny, Michael E., Bejan, Cosmin A.

“…Post marketing safety surveillance depends in part on the ability to detect concerning clinical events at scale. Spontaneous reporting might be an effective…”
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