Search Results - "Desai, Bhavna N"

Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury by Desai, Bhavna N., Singhal, Garima, Watanabe, Mikiko, Stevanovic, Darko, Lundasen, Thomas, Fisher, ffolliott M., Mather, Marie L., Vardeh, Hilde G., Douris, Nicholas, Adams, Andrew C., Nasser, Imad A., FitzGerald, Garret A., Flier, Jeffrey S., Skarke, Carsten, Maratos-Flier, Eleftheria

“…Excess ethanol consumption has serious pathologic consequences. In humans, repeated episodes of binge drinking can lead to liver damage and have adverse…”
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MicroRNA-22 Is a Key Regulator of Lipid and Metabolic Homeostasis by Panella, Riccardo, Petri, Andreas, Desai, Bhavna N, Fagoonee, Sharmila, Cotton, Cody A, Nguyen, Piercen K, Lundin, Eric M, Wagshal, Alexandre, Wang, Da-Zhi, Näär, Anders M, Vlachos, Ioannis S, Maratos-Flier, Eleftheria, Altruda, Fiorella, Kauppinen, Sakari, Pandolfi, Pier Paolo

“…Obesity is a growing public health problem associated with increased risk of type 2 diabetes, cardiovascular disease, nonalcoholic fatty liver disease (NAFLD)…”
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Restored TDCA and valine levels imitate the effects of bariatric surgery by Quante, Markus, Iske, Jasper, Heinbokel, Timm, Desai, Bhavna N, Cetina Biefer, Hector Rodriguez, Nian, Yeqi, Krenzien, Felix, Matsunaga, Tomohisa, Uehara, Hirofumi, Maenosono, Ryoichi, Azuma, Haruhito, Pratschke, Johann, Falk, Christine S, Lo, Tammy, Sheu, Eric, Tavakkoli, Ali, Abdi, Reza, Perkins, David, Alegre, Maria-Luisa, Banks, Alexander S, Zhou, Hao, Elkhal, Abdallah, Tullius, Stefan G

“…Obesity is widespread and linked to various co-morbidities. Bariatric surgery has been identified as the only effective treatment, promoting sustained weight…”
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Leptin in the hindbrain facilitates phosphorylation of STAT3 in the hypothalamus by Desai, Bhavna N, Harris, Ruth B S

“…Leptin receptors (ObRs) in the forebrain and hindbrain have been independently recognized as important mediators of leptin responses. We recently used low-dose…”
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Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice by Douris, Nicholas, Desai, Bhavna N, Fisher, ffolliott M, Cisu, Theodore, Fowler, Alan J, Zarebidaki, Eleen, Nguyen, Ngoc Ly T, Morgan, Donald A, Bartness, Timothy J, Rahmouni, Kamal, Flier, Jeffrey S, Maratos-Flier, Eleftheria

“…Abstract Objective We have previously shown that the consumption of a low-carbohydrate ketogenic diet (KD) by mice leads to a distinct physiologic state…”
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γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis by Hu, Bo, Jin, Chengcheng, Zeng, Xing, Resch, Jon M., Jedrychowski, Mark P., Yang, Zongfang, Desai, Bhavna N., Banks, Alexander S., Lowell, Bradford B., Mathis, Diane, Spiegelman, Bruce M.

“…The sympathetic nervous system innervates peripheral organs to regulate their function and maintain homeostasis, whereas target cells also produce neurotrophic…”
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Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP by Mendoza, Arturo, Tang, Catherine, Choi, Jinyoung, Acuña, Mariana, Logan, Maya, Martin, Adriana G, Al-Sowaimel, Lujain, Desai, Bhavna N, Tenen, Danielle E, Jacobs, Christopher, Lyubetskaya, Anna, Fu, Yulong, Liu, Hong, Tsai, Linus, Cohen, David E, Forrest, Douglas, Wilson, Andrew A, Hollenberg, Anthony N

“…Thyroid hormone (TH) action is essential for hepatic lipid synthesis and oxidation. Analysis of hepatocyte-specific thyroid receptor β1 (TRβ1) knockout mice…”
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Fourth-ventricle leptin infusions dose-dependently activate hypothalamic signal transducer and activator of transcription 3 by Harris, Ruth B S, Desai, Bhavna N

“…Previous studies have shown that very low-dose infusions of leptin into the third or the fourth ventricle alone have little effect on energy balance, but…”
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Long-term estrogen deprivation leads to elevation of Dickkopf-1 and dysregulation of Wnt/β-Catenin signaling in hippocampal CA1 neurons by Scott, Erin L., Zhang, Quan-guang, Han, Dong, Desai, Bhavna N., Brann, Darrell W.

“…► Hippocampal Dkk1 is elevated after long-term ovariectomy and natural aging. ► Hippocampal Wnt signaling is impaired following chronic loss of ovarian…”
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An acute method to test leptin responsiveness in rats by Desai, Bhavna N, Harris, Ruth B S

“…Continuous subcutaneous administration of leptin normalizes blood glucose levels in rodent models of Type 1 and Type 2 diabetes independent of changes in food…”
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Integrated Effects of Leptin in the Forebrain and Hindbrain of Male Rats by Desai, Bhavna N, Harris, Ruth B. S

“…Leptin receptors (ObRs) in the forebrain and hindbrain have been independently recognized as important mediators of leptin responses. It is unclear how leptin…”
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Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition by Huang, Hu, Lee, Seung-Hwan, Sousa-Lima, Inês, Kim, Sang Soo, Hwang, Won Min, Dagon, Yossi, Yang, Won-Mo, Cho, Sungman, Kang, Min-Cheol, Seo, Ji A, Shibata, Munehiko, Cho, Hyunsoo, Belew, Getachew Debas, Bhin, Jinhyuk, Desai, Bhavna N, Ryu, Min Jeong, Shong, Minho, Li, Peixin, Meng, Hua, Chung, Byung-Hong, Hwang, Daehee, Kim, Min Seon, Park, Kyong Soo, Macedo, Maria Paula, White, Morris, Jones, John, Kim, Young-Bum

“…Obesity is a major risk factor for developing nonalcoholic fatty liver disease (NAFLD). NAFLD is the most common form of chronic liver disease and is closely…”
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Blockade of the cerebral aqueduct in rats provides evidence of antagonistic leptin responses in the forebrain and hindbrain by Vaill, Michael I, Desai, Bhavna N, Harris, Ruth B S

“…Previously, we reported that low-dose leptin infusions into the fourth ventricle produced a small but significant increase in body fat. These data contrast…”
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Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat model by Desai, Bhavna N, Maharjan, Radha H, Nampoothiri, Laxmipriya P

“…Polycystic ovarian syndrome (PCOS), characterized by ovulatory infertility and hyperandrogenism, is associated with metabolic complications such as…”
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[delta] T cells and adipocyte IL-17RC control fat innervation and thermogenesis by Hu, Bo, Jin, Chengcheng, Zeng, Xing, Resch, Jon M, Jedrychowski, Mark P, Yang, Zongfang, Desai, Bhavna N

“…The sympathetic nervous system innervates peripheral organs to regulate their function and maintain homeostasis, whereas target cells also produce neurotrophic…”
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Long-Term Estrogen Deprivation Leads to Elevation of Dickkopf-1 and Dysregulation of Wnt/ -Catenin Signaling in Hippocampal CA1 Neurons by Scott, Erin L., Zhang, Quan-guang, Han, Dong, Desai, Bhavna N., Brann, Darrell W.

“…Surgically menopausal women incur a 2–5 fold increased risk for dementia and mortality from neurological diseases, but the mechanisms underlying these…”
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