Search Results - "Desai, Bela S."
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Ionic leakage underlies a gain-of-function effect of dominant disease mutations affecting diverse P-type ATPases
Published in Nature genetics (01-02-2014)“…Boaz Cook and colleagues show that dominant disease-causing mutations in genes encoding P-type ATPases result in a gain-of-function ionic leakage phenotype…”
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F-actin-based extensions of the head cyst cell adhere to the maturing spermatids to maintain them in a tight bundle and prevent their premature release in Drosophila testis
Published in BMC biology (05-05-2009)“…In Drosophila, all the 64 clonally derived spermatocytes differentiate in syncytium inside two somatic-origin cyst cells. They elongate to form slender…”
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The stum Gene Is Essential for Mechanical Sensing in Proprioceptive Neurons
Published in Science (American Association for the Advancement of Science) (14-03-2014)“…Animal locomotion depends on proprioceptive feedback, which is generated by mechanosensory neurons. We performed a genetic screen for impaired walking in…”
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Dynein light chain 1 regulates dynamin-mediated F-actin assembly during sperm individualization in Drosophila
Published in Molecular biology of the cell (01-07-2005)“…Toward the end of spermiogenesis, spermatid nuclei are compacted and the clonally related spermatids individualize to become mature and active sperm. Studies…”
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Ionic leakage underlies a gain-of-function effect of dominant disease mutations affecting diverse P-type ATPases
Published in Nature genetics (01-02-2014)“…Type II P-type ATPases (PAIIs) constitute a family of conserved proteins that actively generate ionic gradients across membranes. Mutations in genes encoding…”
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Dynein Light Chain 1 Regulates Dynamin-mediated F-Actin Assembly during Sperm Individualization in DrosophilaD
Published in Molecular biology of the cell (01-07-2005)“…Toward the end of spermiogenesis, spermatid nuclei are compacted and the clonally related spermatids individualize to become mature and active sperm. Studies…”
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