Search Results - "Desai, Ami"
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The Evolution of Risk Classification for Neuroblastoma
Published in Children (Basel) (11-02-2019)“…Neuroblastoma is a tumor with great clinical heterogeneity. Patients in North America are risk-stratified using a number of features including age at…”
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Age, Diagnostic Category, Tumor Grade, and Mitosis-Karyorrhexis Index Are Independently Prognostic in Neuroblastoma: An INRG Project
Published in Journal of clinical oncology (10-06-2020)“…The Children's Oncology Group (COG) stratifies the treatment of patients with neuroblastoma on the basis of a combination of biomarkers that include age and…”
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Poverty and Targeted Immunotherapy: Survival in Children’s Oncology Group Clinical Trials for High-Risk Neuroblastoma
Published in JNCI : Journal of the National Cancer Institute (01-03-2021)“…Abstract Background Whether social determinants of health are associated with survival in the context of pediatric oncology–targeted immunotherapy trials is…”
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A severe case of delayed transfusion reaction in a patient with sickle cell disease while preparing for allogeneic stem cell transplant
Published in Pediatric blood & cancer (01-08-2024)Get full text
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Outcomes Following GD2-Directed Postconsolidation Therapy for Neuroblastoma After Cessation of Random Assignment on ANBL0032: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (10-12-2022)“…Postconsolidation immunotherapy including dinutuximab, granulocyte-macrophage colony-stimulating factor, and interleukin-2 improved outcomes for patients with…”
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Phase I Study of Stereotactic Body Radiotherapy plus Nivolumab and Urelumab or Cabiralizumab in Advanced Solid Tumors
Published in Clinical cancer research (15-10-2021)“…CD137 agonism and CSF1R blockade augment stereotactic body radiotherapy (SBRT) and anti-programmed death-1 in preclinical models. We evaluated the safety and…”
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Progression-Free Survival and Patterns of Response in Patients With Relapsed High-Risk Neuroblastoma Treated With Irinotecan/Temozolomide/Dinutuximab/Granulocyte-Macrophage Colony-Stimulating Factor
Published in Journal of clinical oncology (20-01-2023)“…Although chemoimmunotherapy is widely used for treatment of children with relapsed high-risk neuroblastoma (HRNB), little is known about timing, duration, and…”
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Efficacy of post‐induction therapy for high‐risk neuroblastoma patients with end‐induction residual disease
Published in Cancer (01-08-2022)“…BACKGROUND High‐risk neuroblastoma patients with end‐induction residual disease commonly receive post‐induction therapy in an effort to increase survival by…”
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Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG)
Published in Neuro-oncology (Charlottesville, Va.) (03-10-2022)“…Abstract Background Entrectinib is a TRKA/B/C, ROS1, ALK tyrosine kinase inhibitor approved for the treatment of adults and children aged ≥12 years with NTRK…”
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Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results
Published in Nature medicine (01-05-2023)“…Neuroblastomas harbor ALK aberrations clinically resistant to crizotinib yet sensitive pre-clinically to the third-generation ALK inhibitor lorlatinib. We…”
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Immunogenomic determinants of tumor microenvironment correlate with superior survival in high-risk neuroblastoma
Published in Journal for immunotherapy of cancer (01-07-2021)“…BackgroundTumor-infiltrating CD8+ T cells and neoantigens are predictors of a favorable prognosis and response to immunotherapy with checkpoint inhibitors in…”
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Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
Published in Cell reports (Cambridge) (25-01-2022)“…In pancreatic ductal adenocarcinoma (PDAC), differentiation of pancreatic stellate cells (PSCs) into myofibroblast-like cancer-associated fibroblasts (CAFs)…”
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Multimodality treatment for recurrent neuroblastoma in the central nervous system
Published in Pediatric blood & cancer (01-04-2023)“…Survival for patients with recurrent central nervous system (CNS) neuroblastoma remains poor. A single‐institutional study demonstrated the potential of…”
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Healthcare utilization disparities among children with high‐risk neuroblastoma treated on Children's Oncology Group clinical trials
Published in Pediatric blood & cancer (01-10-2024)“…Introduction Disparities in relapse and survival from high‐risk neuroblastoma (HRNBL) persist among children from historically marginalized groups even in…”
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Neuroblastoma, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology
Published in Journal of the National Comprehensive Cancer Network (01-08-2024)“…Neuroblastoma is the most common extracranial solid tumor diagnosed in children. This inaugural version of the NCCN Guidelines for Neuroblastoma provides…”
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Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma
Published in Molecules (Basel, Switzerland) (06-07-2022)“…A20FMDV2 is a 20-mer peptide that exhibits high selectivity and affinity for the tumour-related αvβ6 integrin that can compete with extracellular ligands for…”
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Veno-occlusive disease after high-dose busulfan–melphalan in neuroblastoma
Published in Bone marrow transplantation (Basingstoke) (01-03-2020)“…Survival for high-risk neuroblastoma patients is still suboptimal. Although stem cell transplantation (SCT) is used, there is no consensus as to which…”
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Long‐term follow‐up of patients with intermediate‐risk neuroblastoma treated with response‐ and biology‐based therapy: A report from the Children's Oncology Group study ANBL0531
Published in Pediatric blood & cancer (01-08-2024)“…Background We previously reported excellent three‐year overall survival (OS) for patients with newly diagnosed intermediate‐risk neuroblastoma treated with a…”
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Reply to K. Beiske et al
Published in Journal of clinical oncology (01-11-2020)Get full text
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Resource utilization and toxicities after single versus tandem autologous stem cell rescue in high‐risk neuroblastoma using a national administrative database
Published in Pediatric blood & cancer (01-12-2018)“…Background High‐dose chemotherapy with autologous stem cell rescue (HDC‐ASCR) has improved event‐free survival for children with high‐risk neuroblastoma…”
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